Results 141 to 150 of about 8,492,007 (269)

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

The d'--d--d' vertical triad is less discriminating than the a'--a--a' vertical triad in the antiparallel coiled-coil dimer motif. [PDF]

J Am Chem Soc, 2012
Steinkruger JD, Bartlett GJ, Hadley EB, Fay L, Woolfson DN, Gellman SH.   +5 more
europepmc   +1 more source

On Extended d-D Kappa Distribution

Axioms
The thermal Doppler broadening of spectral profiles for particle populations in the absence or presence of potential fields can be described by kappa distributions.
Arak M. Mathai, Hans J. Haubold
doaj   +1 more source

ИндуÑтриÑките водачи ги внеÑуваат VRML, Java и JavaScript во Web [PDF]

, 2016
изваР...
информатика, МЕДИС -
core   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Ја загубивме битката за работната површина, тврди IBM [PDF]

, 2016
изваР...
информатика, МЕДИС -
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Structures and Biogenesis of Fallaxosides D₄, D₅, D₆ and D₇, Trisulfated Non-Holostane Triterpene Glycosides from the Sea Cucumber Cucumaria fallax. [PDF]

Molecules, 2016
Silchenko AS, Kalinovsky AI, Avilov SA, Andryjaschenko PV, Dmitrenok PS, Kalinin VI, Chingizova EA, Minin KV, Stonik VA.   +8 more
europepmc   +1 more source

Non- $$D{\bar{D}}$$ D D ¯ decays into light meson pairs of the D-wave charmonium $$\psi _3(3842)$$ ψ 3 ( 3842 )

European Physical Journal C: Particles and Fields
As a D-wave partner of $$\psi (3770)$$ ψ ( 3770 ) identified by the LHCb Collaboration, $$\psi _3(3842)$$ ψ 3 ( 3842 ) lies between the $$D{\bar{D}}$$ D D ¯ and $$D\bar{D^*}$$ D D ∗ ¯ thresholds.
Zi-Yue Bai, Bao-Jun Lai, Qin-Song Zhou, Xiang Liu   +3 more
doaj   +1 more source

ЕЛЕКТРОÐИКР& ИÐФОРМÐТИКÐ: ОГРÐÐИЧЕРПРИСТÐП [PDF]

, 2016
изваР...
Салиу, Ðрменд, КајевÑка, Ðна   +1 more
core   +1 more source