Results 21 to 30 of about 81 (81)
Evaluation of a Partial Ban on Rx‐Rebates in Germany
Health Economics, EarlyView.ABSTRACT We investigate patients' price sensitivity for prescription (Rx) drugs with regards to patronizing online or brick‐and‐mortar pharmacies. In doing so, we exploit a policy change in Germany that prohibited online pharmacies from granting rebates to one part of the population, the members of the statutory health insurance scheme.
Maximilian M. Gail +3 more
wiley +1 more source
International Journal of Cancer, EarlyView.Bisphosphonates are widely used to treat osteoporosis and to manage bone metastases in patients with breast cancer. Nitrogen‐based bisphosphonates may also broadly reduce cancer risk, but evidence remains inconsistent. This large population‐based data linkage study in women aged > 50 years found that, compared to no use of osteoporosis medicines ...
Karen M. Tuesley +7 more
wiley +1 more source
iRADIOLOGY, EarlyView.Translocator protein 18 kDa (TSPO) is a well‐established biomarker of neuroinflammation and is implicated in the pathophysiology of various neurodegenerative diseases. This study presents [18F]TSPO‐1118 ([18F]3) as a promising positron emission tomography (PET) radioligand for imaging TSPO with high affinity, robust brain uptake, and specificity in ...
Jian Rong +8 more
wiley +1 more source
Journal of Applied Toxicology, EarlyView.ABSTRACT The present study aimed to quantify pesticide residues in environmental matrices and plasma and to evaluate their potential effects on oxidative stress and DNA damage in rural populations of Santa Fe province. Soil and rainwater samples were collected, and biological samples and semistructured surveys were obtained from volunteers in three ...
María Priscila Dechiara +4 more
wiley +1 more source
A Solvent‐Free Synthesis of Imidazo[1,5‐a]pyridines Using CCl4 as an Oxidant
Journal of Heterocyclic Chemistry, EarlyView.A solvent‐free synthesis of imidazo[1,5‐a]pyridines (Impys) using CCl4 as an oxidant reagent and DBU as the base is informed. An array of Impys derived from different benzylic, heteroaryl aldehydes and others was synthesized in moderate to good yields.
Alejandro Castillo‐Baltazar +5 more
wiley +1 more source
Journal of Pharmacy Practice and Research, EarlyView.Abstract Background An increase in the ageing population across long‐term care facilities (LTCFs) has led to an increased risk of polypharmacy. Pharmacist‐led deprescribing (PLD) can reduce these risks but there are limitations to its widespread uptake.
Sefunmi Odetola +3 more
wiley +1 more source
Movement Disorders, EarlyView.Abstract Background Previous studies on calcium channel blockers (CCBs) and Parkinson's disease (PD) risk reached conflicting conclusions. Objectives We examined the relationship between CCBs and PD in the E3N cohort of French women followed for 15 years (2004–2018), while taking into account the potential for reverse causation.
Emilie Moutard +9 more
wiley +1 more source
A Framework for Understanding and Evaluating Localization: The Case of HelpAge International
Public Administration and Development, EarlyView.ABSTRACT Many transnational non‐governmental organizations (TNGOs) are reevaluating their organizational forms and norms as they pursue localization. Localization itself is a contested and multifaceted concept, however, complicating the design, implementation, and evaluation of localization efforts.
Hans Peter Schmitz, George E. Mitchell
wiley +1 more source
Stability studies of cynaropicrin–major sesquiterpene lactone of Cynara cardunculus leaves
Pest Management Science, EarlyView.This study investigated its stability under high temperature and pH, mimicking agronomic extremes and under soil context. Bioassays demonstrated that degradation products exhibited higher phytotoxic activity than cynaropicrin and deacylcynaropicrin. This is the first study about cynaropicrin's stability, characterizing degradation products, and their ...
Daniela Rosa +6 more
wiley +1 more source
Small, EarlyView.Open‐shell quinoids with intrinsic spins are assembled into chiral supramolecular structures via blending with chiral additives. Thermal annealing induces stable co‐crystallization, leading to a 30‐fold amplification of chirality (gabs = 1.23 × 10−2). Significantly, this study represents the first integration of spin‐possessing chiral assemblies into ...
Younghyo Kim +11 more
wiley +1 more source