Results 41 to 50 of about 81 (81)

Patterns of menopausal hormone therapy dispensing over 15 years—A Swedish register‐based cohort study

Acta Obstetricia et Gynecologica Scandinavica, EarlyView.
In this Swedish register‐based cohort study, systemic menopausal hormone therapy dispensing decreased over 15 years, while local therapy increased. Age, cohort effects, and sociodemographic characteristics were associated with differences in dispensing patterns.
Rebecca Götze Eriksson, Fanny Söderquist, Ge Bai, Per Wikman, Diego Hernan Giunta, Inger Sundström Poromaa, Evangelia Elenis, Angelica Lindén Hirschberg, Alkistis Skalkidou, Stavros I. Iliadis   +9 more
wiley   +1 more source

Novel approaches for drug development against chronic primary pain: A systematic review

British Journal of Pharmacology, EarlyView.
Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus, Éva Borbély, Andreas Goebel, Ralf Baron, Zsófia Hajna, Zsuzsanna Helyes   +5 more
wiley   +1 more source

Neurodevelopmental Phenotypes and Brain Anomalies in Individuals With Heterozygous SEMA6A Variants

Clinical Genetics, EarlyView.
SEMA6A plays a role in cell migration and axon guidance in the developing central nervous system. Phenotypes seen in eleven individuals heterozygous for SEMA6A variants included developmental delay, intellectual disability, autism/autistic behaviors, behavioral abnormalities, attention disorders, hypotonia, and brain anomalies.
Evan Burchfiel, Xiaonan Zhao, Nichole M. Owen, Tia Gordon, Mahshid S. Azamian, Eric C. Kao, Fan Xia, Xi Luo, Jill A. Rosenfeld, Seema R. Lalani, Allison P. Ortega, Steven B. Bleyl, Florence Petit, Sulekha Rajagopolan, Bénédicte Demeer, Meredith K. Gillespie, Lijia Huang, Matthew Osmond, Kym M. Boycott, Kyra E. Stuurman, Marjon A. van Slegtenhorst, Haley Soller, Céline Jost, Aurore Garde, Hana Safraou, Laurence Faivre, Victor Faundes, Daryl A. Scott   +27 more
wiley   +1 more source

Self‐reported mental health and the Dobbs decision: Variation by State abortion laws

Contemporary Economic Policy, Volume 43, Issue 2, Page 199-225, April 2025.
Abstract When a US Supreme Court ruling allowed states to ban abortion, women of childbearing age in the states where abortion became illegal reported higher rates of anxiety symptoms compared to similar‐aged women in other states and older women in the same states.
J. Michael Collins, Vivekananda Das
wiley   +1 more source

A Curcumin‐Derived HSP70 Inhibitor Disrupts Lysosomal Function to Suppress Triple‐Negative Breast Cancer Progression

Cell Proliferation, EarlyView.
Novel curcumin‐derived M4 binds HSP70's ATPase domain, disrupting HSP70‐mediated lysosomes‐autophagy pathway to inhibit TNBC growth and metastasis, and synergizes with paclitaxel for potent combination therapy. ABSTRACT Structural modification of curcumin yielded a novel series of 1,4‐pentadien‐3‐one oxime ether derivatives, among which compound M4 ...
Zijian Li, Wanxia Wang, Yuxin Zhou, Tao Zeng, Jian Liu, Yingjie Qing, Xuan Han   +6 more
wiley   +1 more source

A series of (un)fortunate events: Commercial bank interest rates and deposit reallocation during the Great Depression in the Netherlands

The Economic History Review, EarlyView.
Abstract During the global economic crisis of 1929–33, deposits in the Dutch commercial banking sector sharply declined as funds shifted to the government‐guaranteed Post Office Savings Bank and other savings institutions. Unlike earlier studies for neighbouring countries, we demonstrate that this shift was driven less by a flight to safety and more by
Ruben Peeters, Amaury de Vicq de Cumptich   +1 more
wiley   +1 more source

Flexible Contract, Flexible Morale? Microcredit Design and Repayment Discipline

International Economic Review, EarlyView.
ABSTRACT Flexible repayment benefits borrowers, but practitioners fear increased moral hazard. Investigating their concerns requires disentangling repayment choices from repayment capacity, which is typically infeasible in field studies. We use a lab‐in‐the‐field experiment with 645 microcredit borrowers to cleanly identify the effect of repayment ...
Kristina Czura, Anett John, Lisa Spantig
wiley   +1 more source

Impact of Left Bundle Branch Pacing on Left Ventricular Mechanical Efficiency

Journal of Cardiovascular Electrophysiology, EarlyView.
The analysis of myocardial work in 115 consecutive patients receiving left bundle branch area pacing revealed a strong correlation between all myocardial work indices recorded during spontaneous or paced rhythm. Conversely, no significant correlations were observed between myocardial work indices and the R wave peak time in V6 or the V6–V1 interpeak ...
Luca Canovi, Angelo Melpignano, Michele Malagù, Cristina Balla, Ludovica Rita Vocale, Laura Rotondo, Elena Marchetti, Davide Antonio Mei, Marco Zuin, Matteo Bertini, Francesco Vitali   +10 more
wiley   +1 more source

In Vitro Assessment of 3T MRI Effects on Non–3T‐Compatible Cardiac Implantable Electronic Devices

Journal of Cardiovascular Electrophysiology, EarlyView.
ABSTRACT Background The safety of cardiac implantable electronic devices (CIEDs) during 3‐Tesla (3T) MRI remains uncertain, particularly for devices not designed for 3T use. We experimentally evaluated 3T MRI effects on 3T‐compatible and non–3T‐compatible CIEDs.
Yu Fukuoka, Yasuo Sakurai, Risa Kanai, Yuuya Miyazaki, Haruka Yamazaki, Yusuke Koga, Isao Tsukamoto, Yoshifumi Ikeda, Hitoshi Mori, Kazuhisa Matsumoto, Ritsushi Kato   +10 more
wiley   +1 more source

Melanoma and Other Melanistic Lesions in Brown Bullhead Ameiurus nebulosus From Waterbodies in the Northeastern United States and Canada: Identification of Risk Factors

Journal of Fish Diseases, EarlyView.
ABSTRACT Melanistic lesions, including non‐raised black areas due to proliferations of melanocytes and melanomacrophages in the dermis and epidermis, as well as raised black areas consistent with melanoma, are described in brown bullhead (BBH) Ameiurus nebulosus from three water bodies in the northeastern United States and Quebec, Canada.
Vicki S. Blazer, Peter Emerson, Matthew Bodnar, Thomas Jones, David R. Russell, Matthew Pehrson, Cheyenne R. Smith, Danielle Cleveland, Mark J. Henderson, Patricia M. Mazik   +9 more
wiley   +1 more source