Results 41 to 50 of about 92 (92)
Novel approaches for drug development against chronic primary pain: A systematic review
Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus +5 more
wiley +1 more source
Self‐reported mental health and the Dobbs decision: Variation by State abortion laws
Abstract When a US Supreme Court ruling allowed states to ban abortion, women of childbearing age in the states where abortion became illegal reported higher rates of anxiety symptoms compared to similar‐aged women in other states and older women in the same states.
J. Michael Collins, Vivekananda Das
wiley +1 more source
Novel curcumin‐derived M4 binds HSP70's ATPase domain, disrupting HSP70‐mediated lysosomes‐autophagy pathway to inhibit TNBC growth and metastasis, and synergizes with paclitaxel for potent combination therapy. ABSTRACT Structural modification of curcumin yielded a novel series of 1,4‐pentadien‐3‐one oxime ether derivatives, among which compound M4 ...
Zijian Li +6 more
wiley +1 more source
Abstract This paper examines the long‐term effects of ‘Apni Beti Apna Dhan’ (ABAD), a unique conditional cash transfer programme implemented in the north Indian state of Haryana from 1994 to 1998. The programme provided bonds to female beneficiaries at birth, redeemable on attaining 18 years of age, if they remained unmarried. In particular, we examine
Shreya Biswas, Upasak Das
wiley +1 more source
Do re‐employment bonuses increase employment? Evidence from the Idaho Return to Work Bonus programme
Abstract In June 2020, Idaho announced the Return to Work Bonus (RWB) programme, which provided residents who returned to work with bonuses of up to $1500. We present difference‐in‐differences, triple differences, event studies and synthetic control estimates suggesting that the programme may have supported employment and workforce participation ...
Duncan R. Hobbs, Michael R. Strain
wiley +1 more source
Abstract During the global economic crisis of 1929–33, deposits in the Dutch commercial banking sector sharply declined as funds shifted to the government‐guaranteed Post Office Savings Bank and other savings institutions. Unlike earlier studies for neighbouring countries, we demonstrate that this shift was driven less by a flight to safety and more by
Ruben Peeters +1 more
wiley +1 more source
The ribosome‐associated complex regulates cytosolic translation upon mitoprotein‐induced stress
Defects in mitochondrial protein import trigger a stress response. The contribution of translation regulation to such a response is only partially understood. We demonstrate that the deletion of mitochondrial surface proteins (TOM70/TOM71) leads to defects in mitochondrial biogenesis and slow growth.
Jiaxin Qian +7 more
wiley +1 more source
Flexible Contract, Flexible Morale? Microcredit Design and Repayment Discipline
ABSTRACT Flexible repayment benefits borrowers, but practitioners fear increased moral hazard. Investigating their concerns requires disentangling repayment choices from repayment capacity, which is typically infeasible in field studies. We use a lab‐in‐the‐field experiment with 645 microcredit borrowers to cleanly identify the effect of repayment ...
Kristina Czura, Anett John, Lisa Spantig
wiley +1 more source
ABSTRACT Background Atrial pacing at right atrial appendage causes nonphysiologic delays. Bachmann's bundle (BB) pacing preserves synchrony but lacks pediatric data. Case Summary We report the first pediatric combined BB and left bundle branch area pacing in a 9‐year‐old boy (23.5 kg).
Hei‐To Leung +5 more
wiley +1 more source
Abstract This article examines how salient sustainability risks from near‐miss natural disasters influence board composition. Using a difference‐in‐differences design, I find that firms located in counties neighboring disaster‐affected areas significantly increase the presence of directors with sustainability expertise following the disaster.
Bo Wang
wiley +1 more source

