Results 41 to 50 of about 88 (88)

GLP‐1 Receptor Agonists in Brazil: Landscape of Consumption, Safety and Regulation

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Background The escalating use of Glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) is reshaping pharmaceutical consumption patterns and posing unprecedented challenges to healthcare systems worldwide. This study analyzes the landscape of GLP‐1 RA consumption, safety monitoring and regulatory oversight in Brazil.
Renato Lopes Hurtado, Angélica Amorim Amato, Hugo de Luca Corrêa, Dâmaris Silveira   +3 more
wiley   +1 more source

What's the worth of a promise? Evaluating the long‐term effects of a programme to reduce early marriage in India

Economica, EarlyView.
Abstract This paper examines the long‐term effects of ‘Apni Beti Apna Dhan’ (ABAD), a unique conditional cash transfer programme implemented in the north Indian state of Haryana from 1994 to 1998. The programme provided bonds to female beneficiaries at birth, redeemable on attaining 18 years of age, if they remained unmarried. In particular, we examine
Shreya Biswas, Upasak Das
wiley   +1 more source

Regional impacts of international tourism boycott: A China—Japan conflict

Economic Inquiry, EarlyView.
Abstract We examine the regional impacts of the Sino–Japan dispute over the Diaoyu/Senkaku Islands that sparked a Chinese consumer boycott of travel to Japan from August 2012. This boycott caused significant and varied regional impacts across Japan.
Theresa M. Greaney, Kozo Kiyota
wiley   +1 more source

A series of (un)fortunate events: Commercial bank interest rates and deposit reallocation during the Great Depression in the Netherlands

The Economic History Review, EarlyView.
Abstract During the global economic crisis of 1929–33, deposits in the Dutch commercial banking sector sharply declined as funds shifted to the government‐guaranteed Post Office Savings Bank and other savings institutions. Unlike earlier studies for neighbouring countries, we demonstrate that this shift was driven less by a flight to safety and more by
Ruben Peeters, Amaury de Vicq de Cumptich   +1 more
wiley   +1 more source

The ribosome‐associated complex regulates cytosolic translation upon mitoprotein‐induced stress

The FEBS Journal, EarlyView.
Defects in mitochondrial protein import trigger a stress response. The contribution of translation regulation to such a response is only partially understood. We demonstrate that the deletion of mitochondrial surface proteins (TOM70/TOM71) leads to defects in mitochondrial biogenesis and slow growth.
Jiaxin Qian, Annika Nutz, Katja Hansen, Lea Bertgen, Mirita Franz‐Wachtel, Boris Macek, Johannes M. Herrmann, Doron Rapaport   +7 more
wiley   +1 more source

Enzymatic synthesis of bioactive quinolones and (thio)coumarins by fungal type III polyketide synthases

The FEBS Journal, EarlyView.
Quinolones are valuable scaffolds for drug discovery but are rare in nature. Here, we show that two fungal enzymes, AthePKS and FerePKS, can generate 2‐quinolones and two additional heteroaromatic scaffolds. Using AthePKS, we designed an artificial enzymatic cascade towards an antimicrobial quinolone from a simple precursor and implemented it in E ...
Nika Sokolova, Angelina Osipyan, Lili Zhang, Matthew R. Groves, Sandy Schmidt, Kristina Haslinger   +5 more
wiley   +1 more source

Why Can't I Figure This Out? Identity Negotiation and Higher Education Decision Making Among Women With Caring Responsibilities

Gender, Work &Organization, EarlyView.
ABSTRACT Women with unpaid caring responsibilities frequently wrestle with challenges when making decisions about higher education study, asking “Why can't I figure this out?” Statistics have persistently demonstrated that women undertake the majority of unpaid care work, however, unpaid carers are an underrepresented cohort in research, in higher ...
Deborah Munro, Jill Willis, Andrew Gibson, Melinda Laundon   +3 more
wiley   +1 more source

Flexible Contract, Flexible Morale? Microcredit Design and Repayment Discipline

International Economic Review, EarlyView.
ABSTRACT Flexible repayment benefits borrowers, but practitioners fear increased moral hazard. Investigating their concerns requires disentangling repayment choices from repayment capacity, which is typically infeasible in field studies. We use a lab‐in‐the‐field experiment with 645 microcredit borrowers to cleanly identify the effect of repayment ...
Kristina Czura, Anett John, Lisa Spantig
wiley   +1 more source

Dental Caries Prevalence Among Dubai and Northern Emirates Public Schoolchildren: An Epidemiological Retrospective Study (2015–2019)

International Journal of Paediatric Dentistry, EarlyView.
ABSTRACT Background Oral health is a key public health priority in the United Arab Emirates (UAE), yet the effectiveness of the existing programmes is unclear due to limited standardised data. Aim To estimate schoolchildren caries prevalence across UAE over five academic years (2015–2019) and assess the associated factors.
Khawla Humaid Belhoul Alfalasi, Tom Loney, Momen Atieh, Christopher Cardwell, Haifa Hannawi, Maimouneh Qazi, Gerry McKenna   +6 more
wiley   +1 more source

Natural disaster risk salience and the strategic appointment of directors with sustainability expertise

Journal of Financial Research, EarlyView.
Abstract This article examines how salient sustainability risks from near‐miss natural disasters influence board composition. Using a difference‐in‐differences design, I find that firms located in counties neighboring disaster‐affected areas significantly increase the presence of directors with sustainability expertise following the disaster.
Bo Wang
wiley   +1 more source