Results 91 to 100 of about 8,474,652 (256)

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

open access: yesFEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang   +5 more
wiley   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

Editorial: Open-access data, models and resources in neuroscience research

open access: yesFrontiers in Neuroscience, 2023
Ivan Zaletel   +2 more
doaj   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

open access: yesFEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang   +9 more
wiley   +1 more source

ЛапароÑкопÑка апендектомија кај деца во Република Македонија [PDF]

open access: yes, 2017
Acute appendicitis is very common acute surgical condition in childhood that  requires quick and safe treatment with least possible complications.
Симеонов, РиÑто
core   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Measurement of the CP asymmetry in B − → D s − D 0 and B − → D − D 0 decays

open access: yesJournal of High Energy Physics, 2018
The CP asymmetry in B − → D s − D 0 and B − → D − D 0 decays is measured using LHCb data corresponding to an integrated luminosity of 3.0 fb−1, collected in pp collisions at centre-of-mass energies of 7 and 8 TeV. The results are ACPB−→Ds−D0=−0.4±0.5±0.5%
The LHCb collaboration   +791 more
doaj   +1 more source

БезбедноÑта во Ñообраќајот на патиштата – предизвици за јавноздравÑтвен одговор [PDF]

open access: yes, 2018
Road traffic safety is a high-priority public health problem. In the world annually, around 1.25 million people die on roads as a result of road traffic accidents (2.1% of global mortality), and 20-50 million people are injured and remain with life-long ...
Тозија (Tozija), Фимка (Fimka)
core   +1 more source

Home - About - Disclaimer - Privacy