Effects of Antiepileptic Drugs, Carbamazepine and Phenytoin, on Plasma Concentrations of Clozapine and Its N-Desmethyl and N-Oxide Metabolites in Japanese Patients With Schizophrenia. [PDF]
Ikawa K+7 more
europepmc +1 more source
Cинтез в пламени Ñупергидрофобной Ñажи и ее применение
Meruert Nazhipkyzy+7 more
openalex +1 more source
Characterization of ribosome heterogeneity during endothelial to hematopoietic transition
The panorama of ribosome heterogeneity during embryonic hematopoiesis has not yet been portrayed. In this study, utilizing dual‐omics data, the heterogenous dynamic of ribosome during endothelial‐to‐hematopoietic transition has been systemically described. Moreover, stage‐specific upregulation and peripheral localization of RPL27 and RACK1 in hemogenic
Xitong Tian+4 more
wiley +1 more source
Effect of Gene Polymorphism on the Pharmacokinetics and Clinical Outcomes of Rivaroxaban: State-of-the-Art Review. [PDF]
Wang L, Chen G, Hu W, Chen J, He Y.
europepmc +1 more source
The E3 ubiquitin ligase, RNF219, suppresses CNOT6L expression to exhibit antiproliferative activity
We identified RNF219 as a CCR4‐NOT complex‐interacting E3 ubiquitin ligase that targets the CCR4‐NOT subunit CNOT6L for ubiquitination. RNF219 directly binds to the DUF3819 domain of CNOT1 through its putative α‐helix spanning amino acids 521–542. Our findings also suggest that antiproliferative activity of RNF219 is at least partially mediated by ...
Shou Soeda+9 more
wiley +1 more source
Biomineralized engineered <i>Lactococcus lactis</i>-based in situ vaccination enhances antitumor immunity via sequential activation of chemo-immunotherapy. [PDF]
Chen Z+12 more
europepmc +1 more source
Papain‐like protease from SARS‐CoV‐2 plays an important role in the cleavage of the viral polyproteins and in the suppression of the host's immune response. Here, we present the results of an NMR screening study. We identified 86 binding compounds, of which five candidates were chosen for in‐depth analysis.
Dennis J. Pyper+5 more
wiley +1 more source
Who Needs Endoscopic Removal of Food Residue From the Esophagus Before Peroral Endoscopic Myotomy for Esophageal Achalasia and Esophagogastric Junction Outflow Obstruction? [PDF]
Kaizuka M+12 more
europepmc +1 more source