Results 51 to 60 of about 1,320,448 (192)
Archivos Latinoamericanos de NutriciónRESUMEN Las raíces y tubérculos tropicales (RTT) son alimentos básicos de la dieta de los pobladores de estas zonas; son producidos por pequeños y medianos agricultores y se les ha prestado poca atención.
Adriana Blanco-Metzler +2 more
doaj
Development of the addiction profile index (BAPI) adolescent form
Psychiatry and Clinical Psychopharmacology, 2021 Objective: In Turkey, currently there is no addiction scale intended for adolescents. Assessment of the severity of addiction bears great importance for determining the method of treatment for addiction.
Author Name Surname
doaj
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
Psikofarmakolojik araştırmalarda temel istatistik
Psychiatry and Clinical Psychopharmacology, 2021 Psikofarmakolojik araştırmalarda temel istatistik Tüm bilimsel araştırmaların temelini ve en can alıcı noktasını uygun istatistiksel yöntemin iyi belirlenmesi oluşturur. Psikofarmakolojik araştırmalarda da istatistik bu yüzden önemlidir.
Author Name Surname
doaj
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Entangled Religions - Interdisciplinary Journal for the Study of Religious Contact and Transfer, 2022 QS Test 3.3.0 ...
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doaj
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source