Results 51 to 60 of about 1,312,678 (192)

Şizofrenili hastalarda serotonin taşıyıcı gen polimorfizmi

open access: yesPsychiatry and Clinical Psychopharmacology, 2021
Şizofrenili hastalarda serotonin taşıyıcı gen polimorfizmi Amaç: Serotonin taşıyıcı (5-HTT) gen, polimorfik yapıda bir gen olup serotoninin taşınmasındaki rolü nedeniyle psikiyatrik bozuklukların etyolojisinde önemli bir rol oynadığı öne sürülmektedir.
Author Name Surname
doaj  

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

open access: yesFEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer   +7 more
wiley   +1 more source

Letter to the Editor

open access: yesPsychiatry and Clinical Psychopharmacology, 2021
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Author Name Surname
doaj  

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

open access: yesFEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong   +3 more
wiley   +1 more source

Affective-sexual relations: conceptions and representations of middle class young university students = Relações afetivo-sexuais: concepções e representações de jovens universitários de classes médias = Relaciones afectivo-sexuales: concepciones y representaciones de jóvenes universitarios de clase media

open access: yesPsico, 2023
Este estudo teve por objetivo analisar as concepções e representações de jovens universitários de ambos os sexos, pertencentes às classes médias e de diferentes orientações sexuais, a respeito de suas relações afetivo-sexuais.
Risk, Eduardo Name
doaj  

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

open access: yesFEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento   +6 more
wiley   +1 more source

Long Test 3.3.0.13

open access: yesEntangled Religions - Interdisciplinary Journal for the Study of Religious Contact and Transfer, 2022
Long Test 3.3.0 ...
Me My Name
doaj  

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

open access: yesFEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin   +3 more
wiley   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

open access: yesFEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour   +2 more
wiley   +1 more source

OBTENCIÓN DE JARABES DE FRUCTOSA A PARTIR DE HIDROLIZADOS ENZIMÁTICOS DE ALMIDÓN DE ÑAME (Dioscorea alata y Dioscorea rotundata) FRUCTOSE SYRUP OBTENTION FROM ENZYMATIC HYDROLYSED OF YAM STARCH (Dioscorea alata and Dioscorea rotundata)

open access: yesVitae, 2010
En este trabajo se evaluó el rendimiento de la producción de jarabes de fructosa a partir del almidón extraído de dos especies de ñame (Dioscorea alata var. Diamante y Dioscorea rotundata var. Espino).
Jairo G SALCEDO M   +4 more
doaj  

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