Results 31 to 40 of about 18,577,749 (232)

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

FEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty, Kelsi R. Hall, Zachary D. Tillett, Liam S. Turk, James S. Davies, Michael J. Currie, Hamish G. Brown, Sepideh Valimehr, Peter D. Mace, Andrew E. Whitten, Santosh Panjikar, Eric Hanssen, Rachel A. North, Renwick C.J. Dobson   +13 more
wiley   +1 more source

Epilepsy and sudden unexpected death in epilepsy?: Eat more fish! A group hypothesis Epilepsia e morte súbita?: Coma mais peixe! A hipótese de um grupo

Arquivos de Neuro-Psiquiatria, 2009
Epilepsy is the commonest serious neurological disorder and individuals with epilepsy are at higher risk of death than the general population and sudden unexpected death in epilepsy (SUDEP) is the most important direct epilepsy-related cause of death ...
Roberta M. Cysneiros, Vera C. Terra, Hélio R. Machado, Ricardo M. Arida, Marly de Albuquerque, Carla A. Scorza, Esper A. Cavalheiro, Fulvio A. Scorza   +7 more
doaj   +1 more source

Structural and biochemical insights into the thermostable esterase Ta0887 from Thermoplasma acidophilum

FEBS Open Bio, EarlyView.
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey, Miriam Livier Llamas‐García, Gabriela M. Montero‐Morán, Leticia Santos, Samuel Lara‐González   +4 more
wiley   +1 more source

Superovulatory response, production and quality of embryos of cows fed on linseed or canola seed supplemented diets=Resposta super ovulatória, produção e qualidade de embriões de vacas suplementadas com semente de linhaça ou grãos de canola [PDF]

Acta Scientiarum: Animal Sciences, 2012
Superovulatory response, production and embryo quality and the effects of seasonal changes on embryo production of Nellore cows fed on either linseed (n-3) or canola seeds (n-6) were evaluated. Sixteen Nellore cows (550 ± 48.0 kg) were fed on three diets:
Luiz Paulo Rigolon, Fábio Luiz Bin Cavallieri, Rodolpho Martin do Prado, Ivanor Nunes do Prado, Karina Perehouskei Albuquerque, Orlando Rus Barbosa   +5 more
doaj  

The promise of omega-3 against sudden unexpected death in epilepsy: until further notice, it remains innocent, until proven guilty Promessa do ômega-3 contra a morte súbita em epilepsia: até segunda ordem, continua inocente, até que se prove o contrário

Arquivos de Neuro-Psiquiatria, 2012
The present paper highlighted the importance of the recommended levels of fish consumption or omega-3 supplementation in order to minimize the frequency of seizures in people with uncontrolled epilepsy and, especially, to reduce the occurrence of sudden ...
Fulvio Alexandre Scorza, Antonio Carlos Lopes, Roberta Monterazzo Cysneiros, Ricardo Mario Arida, Maurício Rocha e Silva   +4 more
doaj   +1 more source

A minimal cellulosome‐like system in Cellulosilyticum lentocellum

FEBS Open Bio, EarlyView.
Cellulose‐degrading bacteria typically use cellulosomes, large multi‐enzyme complexes on a scaffold protein. In Cellulosilyticum lentocellum, we characterise a far smaller arrangement, a single scaffold bound to one cellulase through a single cohesin‐dockerin interaction.
John Allan, Amias Alstrom‐Moore, Gary W Black   +2 more
wiley   +1 more source

Ação do Ômega 3 nas reservas energéticas e responsividade insulínica em ratos diabéticos aloxanizados

, 2017
Analisou-se a ação do ácido graxo Ômega 3 sobre as reservas glicogênicas e regulação glicêmica de ratos diabéticos aloxanizados. Utilizaram-se ratos machos com idade de 2-3 meses, pesando 180-200g, tratados com ração balanceada e água "ad libitum", os ...
Marcella Damas Rodrigues, Patrícia Carla Paulino, Mariele Almeida Pazotto, Carlos Alberto Da Silva   +3 more
core   +1 more source

The C‐terminal domain of yeast Arginyltransferase1 is essential for its catalytic activity

FEBS Open Bio, EarlyView.
Arginyltransferase 1 (Ate1), a eukaryotic enzyme, catalyses arginylation, transferring arginine from tRNA‐Arg to the amino terminus of the target protein. Overexpression of Ate1 in yeast is lethal and is dependent on arginylation. This study elucidates how mutations in the cofactor‐binding and active site of Ate1 and truncation of its structural ...
Vikas Kumar Yadav, Shweta Shweta, Manisha Malhotra, Vikash Maurya, Akhilesh Kumar   +4 more
wiley   +1 more source

Efeito modulador do ômega-3 contra a genotoxicidade da doxorrubicina em células somáticas de Drosophila melanogaster [PDF]

, 2018
O Ômega-3 é um ácido graxo poliinsaturado, que não é sintetizado pelo organismo, encontrado principalmente em peixes de climas temperados e com importante papel na prevenção de doenças e de cânceres.
Guimarães, Luís Carlos, Nepomuceno, Júlio César   +1 more
core   +1 more source

The promise of omega-3 against sudden unexpected death in epilepsy: until further notice, it remains innocent, until proven guilty

Arquivos de Neuro-Psiquiatria, 2013
The present paper highlighted the importance of the recommended levels of fish consumption or omega-3 supplementation in order to minimize the frequency of seizures in people with uncontrolled epilepsy and, especially, to reduce the occurrence of sudden ...
Fulvio Alexandre Scorza, Antonio Carlos Lopes, Roberta Monterazzo Cysneiros, Ricardo Mario Arida, Maurício Rocha e Silva   +4 more
doaj