Results 171 to 180 of about 996,086 (243)

Established and Emerging Biomarkers to Characterize Persons at Risk for Obesity—Paving the Way for Targeted Clinical Intervention Trials—A Comprehensive Position Paper

Obesity Reviews, EarlyView.
ABSTRACT Despite all efforts, obesity remains a major health concern worldwide, with continuously increasing rates, affecting approx. 14% of the total world population, being as high as 43% in some countries. As obesity is related to numerous comorbidities, including type 2 diabetes, cardiovascular diseases, and some types of cancer, the consequences ...
Farhad Vahid, Victoria Stopa, Laurent Malisoux, Yvan Devaux, Elsa Lamy, Fernando Capela e Silva, Sarah Forberger, Tiziana de Magistris, Antoni Sureda, Margalida Monserrat‐Mesquida, Maria Pérez‐Jiménez, Rajini Nagrani, Maria Giovanna Onorati, Michele Filippo Fontefrancesco, Jonathan Turner, Mahesh S. Desai, Josep Tur, Cristina Bouzas, Gino Gabriel Bonetti, Oliver Riedel, Gitte Ravn‐Haren, Rikke Andersen, Torsten Bohn   +22 more
wiley   +1 more source

In Vitro Antioxidant Activity and Dual-Target Inhibitory Effects of Dipyridamole on α-Amylase and α-Glucosidase: Molecular Mechanisms and Molecular Dynamics Simulations. [PDF]

Biomolecules
Zhao C, Liu H, Shu Y, Wei J, Feng R, Chen L, Bai H, Wang J, Shi D.   +8 more
europepmc   +1 more source

Mentalization and couple relationships: A systematic review of associations and interventions

Psychology and Psychotherapy: Theory, Research and Practice, EarlyView.
Abstract Background Mentalization, the ability to understand one's own and another's thoughts and feelings, is considered important for couple functioning. Many couple‐focused interventions aim to improve mentalization, either as the process through which change occurs or as a central goal of treatment.
Katie Hurman, Madiha Shaikh, Talya Greene, Ciaran O'Driscoll   +3 more
wiley   +1 more source

Semisynthetic Derivatives of Polygodial as α-Glucosidase and α-Amylase Inhibitors: In Vitro Evaluation, Molecular Docking and Molecular Dynamics Simulation. [PDF]

Pharmaceutics
Burgos V, Villegas C, Sanzana C, Oporto B, Schmidt B, Nchiozem-Ngnitedem VA, Iqbal MJ, Paz C.   +7 more
europepmc   +1 more source

Comparative Genome‐Wide Association Studies of Metabolites and Grain‐Related Traits in Common Wheat

Plant Biotechnology Journal, EarlyView.
ABSTRACT The metabolome is highly diverse and the closest layer to phenotype; therefore, it is commonly regarded as a bridge between the genome and phenome in plants. Here, we performed large‐scale metabolome analysis using liquid chromatography–tandem mass spectrometry (LC–MS/MS) and 33 grain‐related traits in a diverse panel of natural accessions and
Guoguo Lv, Yanyan Liu, Bingyang Zhang, Ranran Shen, Maosong Yu, Yongyang Wu, Wanting Du, Xinru Yuan, Congwei Sun, Yan Yan, Wei Chen, Feng Chen   +11 more
wiley   +1 more source

<i>Centaurea pungens</i> Pomel as a potential nutraceutical source: Polyphenol-rich profile, antioxidant capacity, and inhibition of digestive α-amylase. [PDF]

Front Nutr
Mlik R, Fares MA, Mekhadmi NE, Abid A, Bentahar A, Boussebaa W, Benmchih Ayada SA, Kharsi M, Sekour M, Hamouda S, Ali Eltayb W, Yu H, Abdalla M, Alsalme A, Bechelany M, Barhoum A.   +15 more
europepmc   +1 more source

Tonoplast‐Localized ABCC Transporters Enhance Heterologous Production of the Antidiabetic Montbretin A and Its Analogues in Nicotiana benthamiana

Plant Biotechnology Journal, EarlyView.
ABSTRACT The plant‐derived specialized metabolite montbretin A (MbA) is under development as an improved treatment for Type 2 diabetes, a worldwide epidemic. MbA is an acylated flavonol glycoside so far only found in small amounts in montbretia (Crocosmia × crocosmiiflora) corms.
Charlotte Hijmans, Filipe Cabrita Cruz, Lars H. Kruse, Joerg Bohlmann, Sandra Irmisch   +4 more
wiley   +1 more source

Computational Analysis of Balanites aegyptiaca Phytochemicals as Inhibitors of Human Pancreatic α-Amylase. [PDF]

Chem Biodivers
Gautam SK, Paul RK, Jain S, Ahmad I, Mahmood AAR, Patel H, Babu PV, Wahajuddin M, Raza K.   +8 more
europepmc   +1 more source

Unravelling the Intraspecific Variation in Drought Responses in Seedlings of European Black Pine (Pinus Nigra J.F. Arnold)

Plant, Cell &Environment, EarlyView.
ABSTRACT Understanding intraspecific variation in drought tolerance is essential for predicting the adaptive capacity of forest species under climate change. Yet, the molecular basis of this variation remains poorly understood in ecologically and economically important conifers.
Muhammad Ahmad, Almuth Hammerbacher, Clara Priemer, Albert Ciceu, Marta Karolak, Sonja Mader, Sanna Olsson, Johann Schinnerl, Sebastian Seitner, Selina Schöndorfer, Paula Helfenbein, Jakub Jez, Michaela Breuer, Ana Espinosa‐Ruiz, Teresa Caballero, Andrea Ganthaler, Stefan Mayr, Dominik K. Großkinsky, Stefanie Wienkoop, Silvio Schueler, Carlos Trujillo‐Moya, Marcela van Loo   +21 more
wiley   +1 more source

Stratification overcomes ABA-mediated seed dormancy by uncoupling RGL2/ABI5 inhibition from α-amylase expression. [PDF]

Stress Biol
Tian Y, Liu QL, Chen MX, Liu YG.
europepmc   +1 more source