Results 181 to 190 of about 48,861 (198)

Gut Microbiota Regulates Systemic Inflammatory Response and Compensatory Anti‐Inflammatory Response Syndromes by Targeting PF4+ Macrophages in Acute Pancreatitis

open access: yesAdvanced Science, Volume 13, Issue 46, 17 August 2026.
ABSTRACT Acute pancreatitis (AP) begins with pancreatic local inflammation, leading to the onset of systemic inflammatory response syndrome (SIRS), followed by compensatory anti‐inflammatory response syndrome (CARS), which causes immune paralysis and higher mortality rate.
Liwei Liu   +15 more
wiley   +1 more source

Gut Microbiota, Immunity, and Metabolism in the Progression From Chronic Liver Disease to Hepatocellular Carcinoma

open access: yesAdvanced Science, Volume 13, Issue 44, 7 August 2026.
This review explains how chronic liver injury progresses toward hepatocellular carcinoma through interconnected changes in gut microbes, metabolism, immunity, fibrosis, and diet. It highlights microbial metabolites, bile‐acid signaling, immune dysfunction, and nutritional or microbiome‐based interventions as opportunities to identify risk earlier ...
Yi Hu   +5 more
wiley   +1 more source

SuFEx‐Enabled Reprogramming of Flavonoids for Selective α‐Glucosidase Covalent Inhibition

open access: yesAdvanced Science, Volume 13, Issue 47, 24 August 2026.
Selective inhibition of intestinal α‐glucosidase remains limited by poor enzyme specificity and off‐target metabolic effects. Here, SuFEx click chemistry is used to reprogram natural flavonoids into covalent inhibitors with enhanced α‐glucosidase selectivity and controlled reactivity. This strategy enables effective regulation of carbohydrate digestion
Fengyu Guo   +14 more
wiley   +1 more source

Abalone Gut Microbiome Regulators: A Review Synthesizing Gut Physiology, Microorganisms, Diet and the Environment

open access: yesAquaculture, Fish and Fisheries, Volume 6, Issue 4, August 2026.
ABSTRACT Abalone are economically, ecologically and culturally significant marine molluscs, with both wild and farmed populations under pressure due to intrinsic and extrinsic stressors. Abalone performance and health are centred on a highly specialized digestive system supported by a diverse gut microbiome, which enables nutrient assimilation ...
Jinchen Guo   +3 more
wiley   +1 more source

In Vitro Antidiabetic Evaluation and Phytochemical Characterization of Sapindus mukorossi Fruit Pericarp Extract

open access: yesApplied Research, Volume 5, Issue 4, August 2026.
Sapindus mukorossi fruit pericarp is a promising source of polar polyphenols and amphiphilic saponins, with the 70% ethanol extract showing the richest phytochemical profile and strongest α‐amylase inhibition. Its solvent‐dependent bioactive composition suggests potential application in managing postprandial hyperglycemia by modulating dietary starch ...
Keisham Subharani Devi   +3 more
wiley   +1 more source

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