Results 11 to 20 of about 146,148 (156)

Examination the antioxidant potentials and antidiabetic properties of phenolic extracts of some Iranian honeys [PDF]

Journal of Nephropharmacology, 2022
Introduction: In most ancient cultures, honey has been used for both nutritional and medical purposes. Objectives: In this research, phenolic extracts of four Iranian honeys were evaluated to determine the antioxidant potentials using DPPH (2,2-diphenyl ...
Mahmoodreza Moein, Soheila Moein, Fatemeh Farmani, Sahere Rozbehan, Zahra Sabahi   +4 more
doaj   +1 more source

Synthesis of Benzylidene Analogs of Oleanolic Acid as Potential α-Glucosidase and α-Amylase Inhibitors

Frontiers in Chemistry, 2022
A series of benzylidene analogs of oleanolic acid 4a∼4s were synthesized and assessed for their α-glucosidase and α-amylase inhibitory activities. The results presented that all synthesized analogs exhibited excellent-to-moderate inhibitory effects on α ...
Jun-Jie Ke, Jing Lin, Xin Zhang, Xiao-Zheng Wu, Ying-Ying Zheng, Chun-Mei Hu, Yu Kang, Kun Zhang, Zhuang Xiong, Zhi-Qiang Ma   +9 more
doaj   +1 more source

In vitro, in silico and Pharmaco-toxicological Efficiencies of some Triazole Derivatives on Inhibition of Digestive Enzyme Alpha-amylase

Brazilian Archives of Biology and Technology, 2022
Obesity is one of the main health problems associated with a range of diseases. Genetic disposition is related to the risk for obesity but external conditions such lifestyle also increase the incidence.
Elif Ayazoglu Demir, Ahmet Colak, Selcen Celik Uzuner, Ahmet Yasar, Olcay Bekircan, Aylin Kabahasanoglu   +5 more
doaj   +1 more source

α-Amylase inhibition of a certain dietary polyphenol is predominantly affected by the concentration of α-1, 4-glucosidic bonds in starchy and artificial substrates.

Food Research International, 2022
To elucidate why the inhibitory activity of one same polyphenol against α-amylase varies in different works. Seven starchy and three artificial substrates, and a polyphenolic competitive inhibitor, tannic acid (TA) were applied to study the enzyme ...
Jifan Zhang, Caixia Li, Guidan Wang, Junwei Cao, Xi Yang, Xuebo Liu, Lijun Sun   +6 more
semanticscholar   +1 more source

The Physical Adsorption of Gelatinized Starch with Tannic Acid Decreases the Inhibitory Activity of the Polyphenol against α-Amylase

Foods, 2021
The effects of mixing orders of tannic acid (TA), starch, and α-amylase on the enzyme inhibition of TA were studied, including mixing TA with α-amylase before starch addition (order 1), mixing TA with pre-gelatinized starch before α-amylase addition ...
Yueyi Wang, Shuangshuang Li, Fangting Bai, Junwei Cao, Lijun Sun   +4 more
doaj   +1 more source

Inhibition Effect and Molecular Mechanism of Tea Polyphenols on the α-Amylase

Shipin gongye ke-ji, 2022
In present study, the inhibitory effect and molecular mechanism of tea polyphenols on α-amylase were investigated. With the determination of inhibition kinetics, the inhibition of tea polyphenols on α-amylase was estimated.
Hongtu ZHANG, Weijin DONG, Nan CHEN, Qianda XU, Haoxiang GAO, Qiang HE, Weicai ZENG   +6 more
doaj   +1 more source

ANTI-DIABETIC POTENTIAL OF PEPTIDE FROM P. NIRURI REVEALS THROUGH CARBOHYDRATE HYDROLYZING ENZYME INHIBITION ASSAY [PDF]

Science Heritage Journal, 2019
Herb Phyllanthus niruri (P. niruri) is known to have various pharmacological functions including anti-diabetic properties. In this research, protein extracts from different plant parts (leave, fruit and stem) of P. niruri were investigated for their anti-
Noor Hasniza Md Zin, Ainul Mardhiah Mohd Nail   +1 more
doaj   +1 more source

Elucidation of alpha‐amylase inhibition by natural shikimic acid derivates regarding the infrequent uncompetitive inhibition mode and structure–activity relationship

Food Frontiers, 2023
The α‐amylase inhibition and binding behaviors of shikimic acid and its structural analogues were studied. Uncompetitive inhibition characteristic of shikimic acid was identified through several linear transformation equations of enzymatic data ...
Junwei Cao, Jifan Zhang, Ruibo Cao, Wenyue Li, Guidan Wang, Lu Cui, Lijun Sun   +6 more
doaj   +1 more source

Synthesis and bioactivities evaluation of oleanolic acid oxime ester derivatives as α-glucosidase and α-amylase inhibitors

Journal of Enzyme Inhibition and Medicinal Chemistry, 2022
Different oleanolic acid (OA) oxime ester derivatives (3a-3t) were designed and synthesised to develop inhibitors against α-glucosidase and α-amylase. All the synthesised OA derivatives were evaluated against α-glucosidase and α-amylase in vitro.
Xu-Yang Deng, Jun-Jie Ke, Ying-Ying Zheng, Dong-Li Li, Kun Zhang, Xi Zheng, Jing-Ying Wu, Zhuang Xiong, Pan-Pan Wu, Xue-Tao Xu   +9 more
doaj   +1 more source

Inclusion of phenolic compounds from different medicinal plants to increase α-amylase inhibition activity and antioxidants in yogurt

Journal of Taibah University for Science, 2020
Four types of yogurt (Y) were prepared in the presence of rosemary, dill, oregano, and ginger water extracts and refrigerated at 4°C. The effect on post-acidification, α-amylase inhibition activity, total phenolic content (TPC), and antioxidant activity ...
A. Shori
semanticscholar   +1 more source