Results 31 to 40 of about 146,148 (156)

α-/β-Glucosidase and α-Amylase Inhibitory Activities of Roselle (Hibiscus sabdariffa L.) Ethanol Extract

MCBS (Molecular and Cellular Biomedical Sciences), 2017
Background: Diabetes mellitus is a metabolic disease, characterized by hyperglycemia due to disturbance in both insulin secretion and function. One of theurapeutic approaches is to reduce blood glucose levels by inhbiting α-/β-glucosidase and α-amylase ...
Marisca Evalina Gondokesumo, Hanna Sari Widya Kusuma, Wahyu Widowati   +2 more
doaj   +1 more source

Multimodal α-Glucosidase and α-Amylase Inhibition and Antioxidant Effect of the Aqueous and Methanol Extracts from the Trunk Bark of Ceiba pentandra

BioMed Research International, 2020
Postprandial hyperglycemia and oxidative stress are important factors that worsen the health condition of patients with type 2 diabetes. We recently showed that extracts from Ceiba pentandra mitigate hyperglycemia in dexamethasone- and high diet ...
T. B. Nguelefack, C. K. Fofié, E. P. Nguelefack-Mbuyo, A. K. Wuyt   +3 more
semanticscholar   +1 more source

Evaluation of the alpha-glucosidase and alpha-amylase inhibitory potential of the Costus speciosus (J. Koenig) Sm. harvested in Vietnam

Vietnam Journal of Science, Technology and Engineering
This study aimed to evaluate the inhibitory activity of α-glucosidase and α-amylase enzymes using aqueous and 40% ethanol extracts from the aerial parts of Costus speciosus harvested in Binh Phuoc province, tested in vitro.
Oanh Hoang Hua, Nu Thi
doaj   +1 more source

ALPHA-AMYLASE INHIBITORY ACTIVITY OF INHIBITOR PROTEINS IN DIFFERENT TYPES OF COMMERCIAL RICE [PDF]

Science Heritage Journal, 2018
The inhibition of α-amylase enzyme by the inhibitor proteins extracts of all the three types of commercial rice, white rice (WR), brown rice (BR) and glutinous rice (GR) were investigated.
Nur Syazila Ramli, Noor Hasniza Md Zin
doaj   +1 more source

Combined Inhibitory Effects of Procyanidins and Protocatechuic Acid on Starch Digestive Enzymes

Shipin gongye ke-ji
Starch is the main source of energy for the human body. Natural products such as procyanidin (PC) and protocatechuic acid (PCA) can reduce postp'ran'dial blood sugar by controlling the digestion of starch.
Jing ZHANG, Jiefan JIAO, Shaojun YUN, Cuiping FENG, Feier CHENG   +4 more
doaj   +1 more source

Hydroxyproline and proline inhibit α-amylase from isolated barley aleurone layers

Acta Societatis Botanicorum Poloniae, 2014
Previously, we reported that 1 mM hydroxyproline appeared to inhibit the gibberellic acid-induced release of α-amylase from isolated Hordeum vulgare L. cv. Himalaya aleurone layers into an incubation medium.
Craig C. Freudenrich, William V. Dashek
doaj   +1 more source

Multispectroscopy analysis of polystyrene nanoplastic interaction with diastase α-amylase

Ecotoxicology and Environmental Safety, 2022
The digestive enzyme of plant are generally α-amylase. They functions enzyme that breakdown starch into maltose and sugars. This happens in the endosperm of the seed.
Ananthaselvam Azhagesan, Natarajan Chandrasekaran, Amitava Mukherjee   +2 more
doaj   +1 more source

Enzymolysis Modes Trigger Diversity in Inhibitor‐α‐Amylase Aggregating Behaviors and Activity Inhibition: A New Insight Into Enzyme Inhibition

Advanced Science
Inhibitors of α‐amylase have been developed to regulate postprandial blood glucose fluctuation. The enzyme inhibition arises from direct or indirect inhibitor‐enzyme interactions, depending on inhibitor structures.
Junwei Cao, Jifan Zhang, Ruibo Cao, Bin Zhang, Ming Miao, Xuebo Liu, Lijun Sun   +6 more
doaj   +1 more source

Immobilization of Trichoderma harzianum α-Amylase on Treated Wool: Optimization and Characterization

Molecules, 2014
α-Amylase from Trichoderma harzianum was covalently immobilized on activated wool by cyanuric chloride. Immobilized α-amylase exhibited 75% of its initial activity after 10 runs.
Saleh A. Mohamed, Jalaluddin A. Khan, Omar A. M. Al-Bar, Reda M. El-Shishtawy   +3 more
doaj   +1 more source

Fluorinated indeno-quinoxaline bearing thiazole moieties as hypoglycaemic agents targeting α-amylase, and α-glucosidase: synthesis, molecular docking, and ADMET studies

Journal of Enzyme Inhibition and Medicinal Chemistry
Inhibition of α-glucosidase and α-amylase are key tactics for managing blood glucose levels. Currently, stronger, and more accessible inhibitors are needed to treat diabetes.
Nirvana A. Gohar, Eman A. Fayed, Yousry A. Ammar, Ola A. Abu Ali, Ahmed Ragab, Amal M. Mahfoz, Moustafa S. Abusaif   +6 more
doaj   +1 more source