Results 41 to 50 of about 146,148 (156)

α-Amylase inhibition of xanthones from Garcinia mangostana pericarps and their possible use for the treatment of diabetes with molecular docking studies.

Journal of food biochemistry, 2019
Chromatographic separation of the methanol extract of Garcinia mangostana (mangosteen, Guttiferae) dried pericarps led to the isolation and structural characterization of a new xanthone, namely garcimangostin A (5), together with garcixanthone A (1 ...
S. Ibrahim, G. Mohamed, M. Khayat, Sahar Ahmed, H. Abo-Haded   +4 more
semanticscholar   +1 more source

An investigationof the inhibitory effects of dichloromethane and methanol extracts of Salvia macilenta, Salvia officinalis, Salvia santolinifola and Salvia mirzayanii on diabetes marker enzymes, an approach for the treatment diabetes

Clinical Phytoscience, 2022
Background Diabetes mellitus is a type of metabolic disease characterized by elevated blood sugar. The main strategy for its treatment is to inhibit carbohydrate-hydrolyzing enzymes, including α-amylase and α-glucosidase. The aim of the present study was
Hasan Javid, Soheila Moein, Mahmoodreza Moein   +2 more
doaj   +1 more source

Evaluation of Antioxidant Potentials and α-Amylase Inhibition of Different Fractions of Labiatae Plants Extracts: As a Model of Antidiabetic Compounds Properties

BioMed Research International, 2017
In an attempt to identify herbal drugs which may become useful in the prevention of diabetes, antioxidant potentials and α-amylase inhibition by the ethanol extracts of two plants belonging to Lamiaceae family, Otostegia persica and Zataria multiflora ...
S. Moein, Elham Pimoradloo, M. Moein, M. Vessal   +3 more
semanticscholar   +1 more source

Interaction between larval α-amylase of the tomato leaf miner, Tuta absoluta Meyrick (Lepidoptera: Gelechiidae) and proteinaceous extracts from plant seeds

Journal of Plant Protection Research, 2015
The tomato leaf miner, Tuta absoluta Meyrick (Lepidoptera: Gelechiidae), is one of the most destructive pest of solanaceae and it prefers tomato (Solanum lycopersicum L.).
Esmaeily Mojtaba, Bandani Ali Reza
doaj   +1 more source

In vitro study on the hypoglycemic potential of Nicotiana tabacum leaf extracts

Bangladesh Journal of Pharmacology, 2014
Inhibition of some carbohydrate metabolizing enzymes is one of the modes of action of antihyperglycemic agents. The aim of this study was to investigate the in vitro inhibition of α-amylase and α-glucosidase by extracts of N. tabacum leaf.
Mutiu Idowu Kazeem, Semawon Mauton Ogungbe, Gbemisola Morounke Saibu, Oluwaseyi Mayode Aboyade   +3 more
doaj  

α-Amylase Inhibitors: A Review of Raw Material and Isolated Compounds from Plant Source

Journal of Pharmacy & Pharmaceutical Sciences, 2012
- Inhibition of α-amylase, enzyme that plays a role in digestion of starch and glycogen, is considered a strategy for the treatment of disorders in carbohydrate uptake, such as diabetes and obesity, as well as, dental caries and periodontal diseases ...
Paloma Michelle Sales, Paula Monteiro Souza, Luiz Alberto Simeoni, Pérola Oliveira Magalhães, Damaris Silveira   +4 more
doaj   +1 more source

α-Amylase enzyme inhibition relevant to type II diabetes by using functional yogurt with Cinnamomum verum and Stevia rebaudiana

Food and Agricultural Immunology
Type II diabetes prevalence rate is increasing globally. That’s why recently, our research group has worked on functional yogurts made from milk of different species by using functional ingredients to explore their α-amylase inhibitory activity relevant ...
Aneela Hameed, Fartashia Ashraf, Muhammad Junaid Anwar, Adnan Amjad, Muzzamal Hussain, Muhammad Imran, Ahmed Mujtaba, Ishtiaque Ahmad, Muhammad Shoaib Aslam, Ahmed H. El-Ghorab, Mohammed M. Ghoneim, Mohamed E. Shaker, Mohamed A. Abdelgawad, Entessar Al Jbawi   +13 more
doaj   +1 more source

Edible Flowers as Bioactive Food Ingredients with Antidiabetic Potential: A Study on Paeonia officinalis L., Forsythia × intermedia, Gomphrena globosa L., and Clitoria ternatea L.

Plants
Type 2 diabetes is a serious public health problem in the 21st century. To find new substances supporting diabetes therapy, researchers are increasingly paying attention to the biological potential of edible flowers.
Maciej Książkiewicz, Michalina Karczewska, Filip Nawrot, Karolina Grabowska, Marcin Szymański, Judyta Cielecka-Piontek, Elżbieta Studzińska-Sroka   +6 more
doaj   +1 more source

Diosgenin from Dioscorea bulbifera: novel hit for treatment of type II diabetes mellitus with inhibitory activity against α-amylase and α-glucosidase.

PLoS ONE, 2014
Diabetes mellitus is a multifactorial metabolic disease characterized by post-prandial hyperglycemia (PPHG). α-amylase and α-glucosidase inhibitors aim to explore novel therapeutic agents.
Sougata Ghosh, Piyush More, Abhishek Derle, Ajay B Patil, Pramod Markad, Adersh Asok, Navanath Kumbhar, Mahemud L Shaikh, Boppana Ramanamurthy, Vaishali S Shinde, Dilip D Dhavale, Balu A Chopade   +11 more
doaj   +1 more source

Potent Human α-Amylase Inhibition by the β-Defensin-like Protein Helianthamide

ACS Central Science, 2016
Selective inhibitors of human pancreatic α-amylase (HPA) are an effective means of controlling blood sugar levels in the management of diabetes. A high-throughput screen of marine natural product extracts led to the identification of a potent (Ki = 10 pM)
C. Tysoe, L. K. Williams, R. Keyzers, N. Nguyen, Chris A. Tarling, J. Wicki, E. Goddard-Borger, A. Aguda, S. Perry, L. Foster, R. Andersen, G. Brayer, S. Withers   +12 more
semanticscholar   +1 more source