Results 31 to 40 of about 227 (71)

THE CONCISE GUIDE TO PHARMACOLOGY 2019/20: Ion channels

British Journal of Pharmacology, Volume 176, Issue S1, Page S142-S228, December 2019., 2019
The Concise Guide to PHARMACOLOGY 2019/20 is the fourth in this series of biennial publications. The Concise Guide provides concise overviews of the key properties of nearly 1800 human drug targets with an emphasis on selective pharmacology (where available), plus links to the open access knowledgebase source of drug targets and their ligands (www ...
Stephen P H Alexander, Alistair Mathie, John A Peters, Emma L Veale, Jörg Striessnig, Eamonn Kelly, Jane F Armstrong, Elena Faccenda, Simon D Harding, Adam J Pawson, Joanna L Sharman, Christopher Southan, Jamie A Davies, CGTP Collaborators, Richard W Aldrich, Elvir Becirovic, Martin Biel, William A Catterall, Alex C Conner, Paul Davies, Markus Delling, Francesco Di Virgilio, Simonetta Falzoni, Chandy George, Steve AN Goldstein, Stephan Grissmer, Kotdaji Ha, Verena Hammelmann, Israel Hanukoglu, Mike Jarvis, Anders A Jensen, Leonard K Kaczmarek, Stephan Kellenberger, Charles Kennedy, Brian King, Joseph W Lynch, Edward Perez-Reyes, Leigh D Plant, Lachlan D Rash, Dejian Ren, Lucia G Sivilotti, Trevor G Smart, Terrance P Snutch, Jinbin Tian, Charlotte Van den Eynde, Joris Vriens, Aguan D Wei, Brenda T Winn, Heike Wulff, Haoxing Xu, Lixia Yue, Xiaoli Zhang, Michael Zhu   +52 more
wiley   +1 more source

α‐RgIB: A Novel Antagonist Peptide of Neuronal Acetylcholine Receptor Isolated from Conus regius Venom

International Journal of Peptides, Volume 2013, Issue 1, 2013., 2013
Conus venoms are rich sources of biologically active peptides that act specifically on ionic channels and metabotropic receptors present at the neuromuscular junction, efficiently paralyzing the prey. Each species of Conus may have 50 to 200 uncharacterized bioactive peptides with pharmacological interest.
Maria Cristina Vianna Braga, Arthur Andrade Nery, Henning Ulrich, Katsuhiro Konno, Juliana Mozer Sciani, Daniel Carvalho Pimenta, Ayman El-Faham   +6 more
wiley   +1 more source

α9-Nicotinic Acetylcholine Receptors Contribute to the Maintenance of Chronic Mechanical Hyperalgesia, but Not Thermal or Mechanical Allodynia

Molecular Pain, 2014
Background: The current pharmacological treatments for chronic pain are limited. The first analgesic drug approved for clinical use in decades that has a novel molecular target is the synthetic version of a naturally occurring conotoxin.
Sarasa Mohammadi, Macdonald J Christie
doaj   +1 more source

The Concise Guide to PHARMACOLOGY 2025/26: Ion channels

British Journal of Pharmacology, Volume 182, Issue S1, Page S152-S241, December 2025.
The Concise Guide to Pharmacology 2025/26 marks the seventh edition in this series of biennial publications in the British Journal of Pharmacology. Presented in landscape format, the guide provides a comparative overview of the pharmacology of drug target families. The concise nature of the Concise Guide refers to the style of presentation, being clear,
Stephen P. H. Alexander, Jörg Striessnig, Alasdair J. Gibb, Alistair A. Mathie, Emma L. Veale, Eamonn Kelly, Chloe J. Peach, Jane F. Armstrong, Elena Faccenda, Simon D. Harding, Christopher Southan, Jamie A. Davies, Richard W. Aldrich, Bernard Attali, Austin M. Baggetta, Elvir Becirovic, David J. Beech, Martin Biel, Roslyn M. Bill, Ana I. Caceres, William A. Catterall, Han Chow Chua, Alex C. Conner, Henry Danahay, Paul Davies, Katrien De Clerq, Markus Delling, Francesco Di Virgilio, Simonetta Falzoni, Wei Fang, Stefanie Fenske, Anna Fortuny‐Gomez, Samuel Fountain, George K. Chandy, Mohammad‐Reza Ghovanloo, Steve A. N. Goldstein, Martin Gosling, Christian Grimm, Stephan Grissmer, Kotdaji Ha, Tim G. Hales, Verena Hammelmann, Israel Hanukoglu, Meiqin Hu, Ad P. Ijzerman, Sairam V. Jabba, Mike Jarvis, Anders A. Jensen, Sven E. Jordt, Leonard K. Kaczmarek, Stephan Kellenberger, Charles Kennedy, Brian King, Philip Kitchen, Qiang Liu, Joseph W. Lynch, Rian W. Manville, Jessica Meades, Verena Mehlfeld, Annette Nicke, Stefan Offermanns, Edward Pérez‐Reyes, Leigh D. Plant, Stephan A. Pless, Lachlan D. Rash, Dejian Ren, Hussein N. Rubaiy, Mootaz M. Salman, Werner Sieghart, Lucia G. Sivilotti, Trevor G. Smart, Terrance P. Snutch, Paolo Tammaro, Jinbin Tian, James S. Trimmer, Charlotte Van den Eynde, Paola Vergani, Joris Vriens, Stephen G. Waxman, Aguan D. Wei, Brenda T. Winn, Heike Wulff, Haoxing Xu, Fan Yang, Lixia Yue, Xiaoli Zhang, Michael Zhu   +86 more
wiley   +1 more source

Conus regius-Derived Conotoxins: Novel Therapeutic Opportunities from a Marine Organism. [PDF]

Mar Drugs, 2022
Margiotta F, Micheli L, Ciampi C, Ghelardini C, McIntosh JM, Di Cesare Mannelli L.   +5 more
europepmc   +1 more source

α7- and α9-Containing Nicotinic Acetylcholine Receptors in the Functioning of Immune System and in Pain. [PDF]

Int J Mol Sci, 2023
Shelukhina I, Siniavin A, Kasheverov I, Ojomoko L, Tsetlin V, Utkin Y.   +5 more
europepmc   +1 more source

Cone snail species off the Brazilian coast and their venoms: a review and update. [PDF]

J Venom Anim Toxins Incl Trop Dis, 2023
Fiorotti HB, Figueiredo SG, Campos FV, Pimenta DC.   +3 more
europepmc   +1 more source

Exploring Cholinergic Compounds for Peripheral Neuropathic Pain Management: A Comprehensive Scoping Review of Rodent Model Studies. [PDF]

Pharmaceuticals (Basel), 2023
Montigné E, Balayssac D.
europepmc   +1 more source

Fifty Years of Animal Toxin Research at the Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry RAS. [PDF]

Int J Mol Sci, 2023
Tsetlin V, Shelukhina I, Kozlov S, Kasheverov I.   +3 more
europepmc   +1 more source

Synthesis of Cystine-Stabilised Dicarba Conotoxin EpI: Ring-Closing Metathesis of Sidechain Deprotected, Sulfide-Rich Sequences. [PDF]

Mar Drugs, 2023
Thomson AL, Robinson AJ, Belgi A.
europepmc   +1 more source