Results 91 to 100 of about 114,902,985 (177)

Influence of chemical reagents and UV irradiation on the activity of Penicillium canescens α-galactosidase

The Ukrainian Biochemical Journal, 2018
Investigations of the influence of chemical and physical factors on the conformational and functional properties of enzymes make a significant contribution to the study of the mechanism of action of industrially important proteins.
N. V. Borzova, L. D. Varbanets
doaj   +1 more source

IMOBILIZAÇÃO DA ENZIMA Î’-GALACTOSIDASE DE Aspergillus oryzae EM RESINAS DE TROCA IÔNICA

, 2012
Este trabalho apresenta como objetivo estudar o processo de imobilização da enzima β-galactosidase de Aspergillus oryzae por adsorção, utilizando como suporte resinas de troca iônica Duolite A-568, Duolite S-761, Dowex Marathon A, Dowex Marathon C e Amberlite 252 Na.
Santana, Larissa Nayhara Soares, Guidini, Carla Zanella, Ribeiro, Eloízio Júlio   +2 more
openaire   +1 more source

Effect of medium composition and fermentation conditions on α-galactosidase production by Aspergillus niger v. Tiegh

浙江大学学报. 农业与生命科学版, 2009
“One-factor-at-a-time” method was applied to investigate the medium composition and fermentation conditions for α-galactosidase production by a mutant strain Aspergillus niger v.
XU Yao-xing, LI Yan-li, XU Shao-chun, LIU Yong, YAO Xiao-hong   +4 more
doaj   +1 more source

Correlation between GLA variants and alpha-Galactosidase A profile in dried blood spot: an observational study in Brazilian patients

Orphanet Journal of Rare Diseases, 2020
Background Fabry disease is a rare X-linked inherited disorder caused by deficiency of α-Galactosidase A. Hundreds of mutations and non-coding haplotypes in the GLA gene have been described; however, many are variants of unknown significance, prompting ...
Patrícia Varela, Gianna Mastroianni Kirsztajn, Fabiana L. Motta, Renan P. Martin, Lauro T. Turaça, Henrique L. F. Ferrer, Caio P. Gomes, Priscila Nicolicht, Maryana Mara Marins, Juliana G. Pessoa, Marion C. Braga, Vânia D’Almeida, Ana Maria Martins, João B. Pesquero   +13 more
doaj   +1 more source

Stereochemical course of hydrolytic reaction catalyzed by alpha-galactosidase from cold adaptable marine bacterium of genus Pseudoalteromonas

Frontiers in Chemistry, 2014
The recombinant α-galactosidase of the marine bacterium (α-PsGal) was synthesized with the use of the plasmid 40Gal, consisting of plasmid pET-40b (+) (Novagen) and the gene corresponding to the open reading frame of the mature α-galactosidase of marine ...
Irina Yu Bakunina, Larissa A Balabanova, Vasiliy A Golotin, Lyubov V Slepchenko, Lyubov V Slepchenko, Vladimir V Isakov, Valeriy A Rasskazov   +6 more
doaj   +1 more source

α-D-Gal-cyclophellitol cyclosulfamidate is a Michaelis complex analog that stabilizes therapeutic lysosomal α-galactosidase A in Fabry disease [PDF]

Fabry disease is an inherited lysosomal storage disorder that is characterized by a deficiency in lysosomal α-D-galactosidase activity. One current therapeutic strategy involves enzyme replacement therapy, in which patients are treated with a recombinant
Wu L, Hedberg C, Schaaf A, Davies GJ, Rovira C, Ferraz MJ, van der Marel GA, Raich L, Rowland RJ, Codee JDC, Overkleeft HS, Aerts JMFG, Artola M, Kytidou K   +13 more
core   +4 more sources

Synthesis of lipophilic 1-deoxygalactonojirimycin derivatives as D-galactosidase inhibitors

Beilstein Journal of Organic Chemistry, 2010
N-Alkylation at the ring nitrogen of the D-galactosidase inhibitor 1-deoxygalactonojirimycin with a functionalised C6 alkyl chain followed by modification with different aromatic substituents provided lipophilic 1-deoxygalactonojirimycin derivatives ...
Georg Schitter, Elisabeth Scheucher, Andreas J. Steiner, Arnold E. Stütz, Martin Thonhofer, Chris A. Tarling, Stephen G. Withers, Jacqueline Wicki, Katrin Fantur, Eduard Paschke, Don J. Mahuran, Brigitte A. Rigat, Michael Tropak, Tanja M. Wrodnigg   +13 more
doaj   +1 more source

Creation of a Recombinant Bacteriophage to Express Beta-Galactosidase

, 2014
Human illness caused by the consumption of food contaminated with pathogenic bacteria is a worldwide problem that requires new detection methods to solve.
Heather Talbott (10083040), Catherine Swedberg (10083037)   +1 more
core   +1 more source

Difficulties in the diagnosis of Fabry disease in real clinical practice

Acta Biomedica Scientifica
Background. Fabry disease is a genetically determined disease in which deficiency or complete absence of α-galactosidase A (GLA/AGAL) activity is formed.
A. A. Petrukhina, S. N. Nasonova, I. V. Zhirov, Yu. F. Osmolovskaya, S. N. Tereshchenko, F. N. Paleev   +5 more
doaj   +1 more source

Immobilized preparation of cold-adapted and halotolerant Antarctic β-galactosidase as a highly stable catalyst in lactose hydrolysis [PDF]

FEMS Microbiology Ecology, 2007
Krzysztof Makowski, Aneta Białkowska, Mirosława Szczęsna-Antczak, Halina Kalinowska, Józef Kur, Hubert Cieśliński, Marianna Turkiewicz   +6 more
openaire   +1 more source