Results 151 to 160 of about 1,799,019 (357)

New Perspectives on the Risks of Hydroxylated Polychlorinated Biphenyl (OH-PCB) Exposure: Intestinal Flora α-Glucosidase Inhibition

Toxics
Polychlorinated biphenyls (PCBs) are a group of colorless and odorless environmental pollutants with a wide range of toxic effects. Some PCBs, especially less chlorinated ones, will rapidly undergo phase I metabolism after entering the body, and ...
Guoqiang Qin, Ruoyong Jia, Juntang Xue, Li Chen, Yang Li, Weiming Luo, Xiaomin Wu, Tianfeng An, Zhongze Fang   +8 more
doaj   +1 more source

The role of olive β-glucosidase in shaping the phenolic profile of virgin olive oil

Food Research International, 2012
The main objective of this work was to investigate the biochemical factors directly affecting the phenolic profile of virgin olive oil (VOO) such as the content of phenolic glycosides and the β-glucosidase activity present in the olive fruit. The phenolic compositions of VOO from two olive cultivars, Arbequina and Picual, were studied throughout the ...
Romero-Segura, Carmen, García-Rodríguez, Rosa, Sánchez-Ortiz, Araceli, Sanz, Carlos, Pérez Rubio, Ana Gracia   +4 more
openaire   +2 more sources

Optimization of bioactive compounds extraction from Rosa canina L. pseudofruit through the action of two hydrolytic enzyme preparations

Journal of Chemical Technology &Biotechnology, EarlyView.
Abstract BACKROUND The pseudo‐fruit of Rosa canina L. is a rich source of bioactive compounds with antioxidant, anti‐inflammatory, anti‐cancer, anti‐diabetic, anti‐aging, and antimicrobial activities. The aim of the present study is the optimization of a green process based on the action of two hydrolytic enzyme preparations, namely Pectinex® Ultra ...
Zafeiria Lemoni, Styliani Kalantzi, Theopisti Lymperopoulou, Andromachi Tzani, Georgios Stavropoulos, Anastasia Detsi, Diomi Mamma   +6 more
wiley   +1 more source

Structural and biochemical data of Trichoderma harzianum GH1 β-glucosidases

Data in Brief, 2017
Here the statistics concerning X-ray data processing and structure refinement are given, together with the substrate preference analysis for ThBgl1 and ThBgl2. Finally, the analysis of the influence of temperature and pH on the activities of both enzymes are shown.
Renata N. Florindo, Valquiria P. Souza, Hemily S. Mutti, Lívia R. Manzine Margarido, Cesar Camilo, Sandro R. Marana, Igor Polikarpov, Alessandro S. Nascimento   +7 more
openaire   +3 more sources

Synthesis of Sulochrin-125I and Its Binding Affinity as α-Glucosidase Inhibitor Using Radioligand Binding Assay (RBA) Method [PDF]

, 2014
Most of diabetes patients have type 2 diabetes mellitus or non insulin dependent diabetes mellitus. Treatment of type 2 diabetes mellitus can be conducted by inhibiting the α-glucosidase enzyme which converts carbohydrates into glucose.
Ariyanto, A. (A), Kardono, L. B. (L), Lestari, W. (W), Setiyowati, S. (S), Susilo, V. Y. (V), Triningsih, T. (Triningsih), Widayati, P. (P), Yanuar, A. (A)   +7 more
core  

Recycling of hazelnut waste: Antidiabetic properties of soy lecithin nanoparticles and their in vitro anti‐proliferative effects in tumor cell lines

Journal of the Science of Food and Agriculture, EarlyView.
Abstract BACKGROUND Hazelnuts and foods produced using hazelnuts are consumed with pleasure, but it is important to evaluate the waste generated during hazelnut processing and determine their usage methods. RESULTS This study was conducted to determine the changes in bioactive components, bioaccessibility and antidiabetic activity of nanoparticles ...
Mehmet Ali Temiz, Emine Okumus
wiley   +1 more source

Rapidly screening of α-glucosidase inhibitors from Dioscorea opposita Thunb. peel based on rGO@Fe3O4 nanocomposites microreactor

Journal of Enzyme Inhibition and Medicinal Chemistry, 2018
Present study aimed to immobilise the α-glucosidase on suitable supports to construct enzymatic microreactors and their subsequent applicability in efficient inhibitor screening from the Chinese Yam (Dioscorea opposita Thunb.) peel.
Songsong Zhang, Beibei Qiu, Jinhua Zhu, Weiping Hu, Fanyi Ma, M. Z. H. Khan, Xiuhua Liu   +6 more
doaj   +1 more source

Avaliação e Caraterização da Ação Inibitória de Iminociclitóis na Atividade α-Glucosidase de Enterócitos de Mamífero [PDF]

, 2013
A diabetes, em particular a diabetes mellitus tipo 2, constitui um distúrbio metabólico que se carateriza por glicemias aumentadas resultantes de diminuição da libertação e/ou ação da insulina.
Antunes, Célia M, Burke, Anthony J, Carreiro, Elisabete P, Costa, Ana R, Louro, Patricia R, Vannuchi, Nicholas   +5 more
core  

In silico prediction and structural characterization of multifunctional bioactive peptides released from olive proteins

Journal of the Science of Food and Agriculture, EarlyView.
Abstract BACKGROUND Olive (Olea europaea L.) byproducts, such as seeds and leaves, are abundant agro‐industrial residues and represent underexplored protein sources with potential health relevance. However, the repertoire of bioactive peptides that may be released from olive proteins during gastrointestinal digestion remains poorly characterized.
Teresa Gonzalez‐de la Rosa, Luna Barrera‐Chamorro, Africa Fernandez‐Prior, Elvira Marquez‐Paradas, Maria Torrecillas‐Lopez, Fernando Rivero‐Pino, Sergio Montserrat‐de la Paz   +6 more
wiley   +1 more source

Benzonate derivatives of acetophenone as potent α-glucosidase inhibitors: synthesis, structure–activity relationship and mechanism

Journal of Enzyme Inhibition and Medicinal Chemistry, 2019
In this article, 23 compounds (6 and 7a–7v) were prepared and evaluated for their in vitro α-glucosidase inhibitory activity. The compounds 7d, 7f, 7i, 7n, 7o, 7r, 7s, 7u, and 7v displayed the α-glucosidase inhibition activity with IC50 values ranging ...
Wen-Jia Dan, Qiang Zhang, Fan Zhang, Wei-Wei Wang, Jin-Ming Gao   +4 more
doaj   +1 more source