Darier disease—A review highlighting new insights from the Darier Disease International Task Force
This review provides a global, clinically focused overview of DD, detailing cutaneous and extracutaneous manifestations, disease classification and severity scoring. It emphasizes early recognition, multidisciplinary management and practical guidance for dermatologists to apply evidence‐based care in diverse skin phototypes. Abstract Darier disease (DD)
Sofia Labbouz +49 more
wiley +1 more source
Antioxidant, antibacterial, in vitro, and in silico α-glucosidase inhibition activities and chemical profiling of Usnea cornuta Korb. [PDF]
Karki D +4 more
europepmc +1 more source
Cell‐Specific Expression and Cellular Compartmental Regulation in Camptothecin Biosynthesis
ABSTRACT Plant secondary metabolites such as monoterpenoid indole alkaloids (MIAs) show tightly regulated biosynthesis and accumulation in specific organelles of distinct cell types. However, the cell‐specific expression patterns of anticancer MIA camptothecin biosynthetic genes in Ophiorrhiza pumila and the regulatory mechanisms of camptothecin ...
Xiaolong Hao +12 more
wiley +1 more source
Synthesis, characterization, and α-glucosidase inhibitory activity of methyl proline derivatives of phenylpropanoid. [PDF]
Zhang W +8 more
europepmc +1 more source
Deciphering Role of Endophytes in Plant Defences and Biotic Stress Resilience Across Families
ABSTRACT Plant families generate distinct repertoires of specialised metabolites that govern their biotic interactions. Endophytes strengthen host plant defence mechanisms and tolerance to biotic challenges by upregulating metabolite biosynthesis, modifying precursor compounds into more potent forms, or by directly synthesising analogous defence ...
S. Aneeqa Noor +4 more
wiley +1 more source
Molecular Basis for the Divergent Inhibition of α-Amylase and α-Glucosidase by Phenolic Acids: The Critical Role of Hydroxyl Substitution. [PDF]
Yang S +8 more
europepmc +1 more source
ABSTRACT In this study, we analyzed a unique Nicotiana tabacum BY‐2 line that was gradually adapted to and subsequently maintained in 190 mM NaCl for over 15 years. Years of continuous high salinity shaped a stable “new homeostasis” in BY‐2 suspension cells. Salt‐adapted cells were smaller and formed tighter clusters. Metabolomics revealed constitutive
Anita Rzadkiewicz +8 more
wiley +1 more source
Macroalgal Peptides with Predicted α-Glucosidase Inhibitory Activity: Preparation and Molecular Docking. [PDF]
Ghelichi S +4 more
europepmc +1 more source
Asep Sukohar +3 more
openaire +1 more source
Abstract The aim of this systematic review and meta‐analysis was to evaluate comprehensively the therapeutic potential of Abelmoschus esculentus (okra) supplementation across the diabetes spectrum of key metabolic risk factors. A search was conducted in PubMed, Scopus, Web of Science, EMBASE and the Cochrane Library, up to 23 July 2025, to identify ...
Ali Jafari +7 more
wiley +1 more source

