Results 211 to 220 of about 1,767,652 (263)

Malectin Alleviates Endoplasmic Reticulum Stress in Gestational Diabetes Mellitus via Glycoprotein Quality Control Mechanisms

Advanced Science, Volume 13, Issue 46, 17 August 2026.
Malectin alleviates high glucose‐induced ER stress and damage in placental trophoblasts, a function dependent on its six critical carbohydrate‐binding residues. In a GDM mouse model, administration of TAT‐Malectin ameliorated hyperglycemia and placental ER stress and prevented fetal macrosomia.
Jiahui Zhu, Yumeng Zhang, Ye Wang, Xiaoyu Zhu, Ailin Yuan, Weijing Yin, Huangmin Yu, Xuemin Pang, Yufeng He, Yuchen Wang, Tong Wang, Yong Li, Yunlong Si   +12 more
wiley   +1 more source

Oral Delivery Systems for Food‐Derived Bioactive Peptides: Enhancing Stability, Bioavailability, and Health Benefits

Advanced Science, Volume 13, Issue 46, 17 August 2026.
Advanced delivery systems—including nanoparticles, nanoemulsions, liposomes, and hydrogels—protect food‐derived bioactive peptides from gastrointestinal degradation and bitterness. These systems enable pH‐responsive release, enhance intestinal absorption, and improve therapeutic efficacy against oxidative stress, metabolic disorders, cancer, and ...
Yu Xu, Fan Li, Runan Zhao, Tao Shu, Weihong Min, Bei‐Wei Zhu   +5 more
wiley   +1 more source

Antioxidant, Antidiabetic and Cytoprotective Activities of Synthetic Chloro‐Curcumin Derivatives in C2C12 Myotubes

Applied Research, Volume 5, Issue 4, August 2026.
Structural reengineering of curcumin generated derivatives with antioxidant, cytoprotective and glucose‐modulating activities. These compounds improved cellular responses to hyperglycaemic stress in C2C12 myotubes, highlighting their potential as candidates for managing oxidative stress–related metabolic disorders, particularly type 2 diabetes mellitus.
Adesola Oluwaseun Adeleye, Oluwafemi Omoniyi Oguntibeju, Salam Titinchi, Chinyerum Sylvia Opuwari   +3 more
wiley   +1 more source

Impact of Metformin Use on Clinical and Pathological Outcomes in Breast Cancer Patients With Type 2 Diabetes

Cancer Reports, Volume 9, Issue 8, August 2026.
ABSTRACT Background Breast cancer is the most common malignancy in women, and its incidence is increasing worldwide. Type 2 diabetes mellitus (T2DM) is a significant comorbidity in patients with breast cancer that negatively affects prognosis. Metformin, a first‐line antidiabetic drug, has been suggested to possess antineoplastic properties. This study
Ensiyeh Bahadoran, Monir Mirzadeh, Mohsen Jafari, Yazdan Zafari, Sahar Moghbelinejad   +4 more
wiley   +1 more source

Moutan Cortex Extract Mediates Diabetic Retinopathy by Blocking the ROS‑Triggered HIF‐1α/VEGF Axis in Retinal Pigment Epithelial Cells

eFood, Volume 7, Issue 4, August 2026.
Schematic diagram of the mechanism by which Moutan Cortex extract (MCE) ameliorates DR. MCE alleviates retinal structural damage and reduces neovascular lesions by downregulating the ROS/HIF‐1α/VEGF signaling axis. ABSTRACT Moutan Cortex is a functional food ingredient with multiple health benefits, but its effects on diabetic retinopathy (DR) remain ...
Mei‐rong Li, Xian‐yi Zhang, Wan‐ying Zhang, Nan Chen, Wei‐wei Lv, Tian‐yu Liu, Xu Guo, Ying‐ying Chen, Meng‐qi Zhang, Shu‐tao Sun, Mu‐xuan Wang, Qi‐dong Ren, Chao Liu, Jin‐yue Sun   +13 more
wiley   +1 more source

Optimizing the Anti‐Inflammatory Efficacy of Pakistani Spice Blends: A Farm‐to‐Fork Analysis of Phytochemical Synergy and Processing Stability

eFood, Volume 7, Issue 4, August 2026.
This review aims to evaluate the anti‐inflammatory potential of these spice blends, emphasizing their synergistic mechanisms, and to investigate how cultivation practices, post‐harvest processing, and environmental stressors shape their medicinal efficacy. By addressing this gap, it seeks to provide a comprehensive framework for integrating traditional
Qudrat Ullah, Waqas Haider, Farhang Hameed Awlqadr, Ahmed Bilal, Muhammad Tayyab Arshad, Emmanuel Laryea   +5 more
wiley   +1 more source

Total Protein and 10‐Hydroxy‐2‐Decenoic Acid Content, In Vitro Bioaccessibility, Antibacterial, and Antidiabetic Properties of Royal Jelly Collected at Different Harvesting Times

Food Science &Nutrition, Volume 14, Issue 8, August 2026.
In this study, the total protein content and 10‐hydroxy‐2‐decenoic acid content were determined in royal jelly collected at the 72 and 144 h. In vitro bioaccessibility, antibacterial, and antidiabetic properties of royal jelly collected at the 72 and 144 h were also determined. ABSTRACT Royal jelly has received interest as a functional food.
Eyuel Welelaw, Abera Belay, Tadele Alemu, Teferi Damto, Admasu Addi, Mesfin Getachew Tadesse, Endale Amare, Feriehiwote Weldeyohanis Gebremariam, Ibrahim Ahmed Sherif, Henock Woldemichael Woldemariam   +9 more
wiley   +1 more source

Therapeutic Potential of Water‐Based Anatolian Propolis Extract Against CAF Diet‐Induced Obesity and Its Metabolic Complications

Food Science &Nutrition, Volume 14, Issue 8, August 2026.
Water‐based Anatolian propolis extract attenuates CAF diet‐induced obesity‐related metabolic disturbances by improving dyslipidemia, hepatic injury, adipokine imbalance, and inflammatory status in C57BL/6 mice. ABSTRACT This study investigates the anti‐obesity effects of water‐based Anatolian propolis extract in mice with a cafeteria diet‐induced ...
Mehmet Kemal, Elif Şahin, Ali Kulaber, Sevil Kör, Ahmet Alver, Engin Yenilmez, Sevgi Kolaylı   +6 more
wiley   +1 more source

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Studies on the inhibition of α-glucosidase by biflavonoids and their interaction mechanisms

Food Chemistry, 2023
Biflavonoids are a kind of polyphenol compounds with numerous biological functions. However, the potential inhibitory activities of biflavonoids on α-glucosidase are yet unknown.
Xin Peng, Mengfan Wang, Jichen Yang
exaly   +2 more sources

Inhibition of starch digestion by phenolic acids with a cinnamic acid backbone: Structural requirements for the inhibition of α-amylase and α-glucosidase.

Food Chemistry, 2023
This study investigated the inhibition mechanism of cinnamic acid-based phenolic acids (cinnamic acid: CIA, 3,4-dimethoxy cinnamic acid: 3,4-mCIA, caffeic acid: CA, ferulic acid: FA) on starch digestion.
Meihui Yu, Song Zhu, Dejian Huang, Xiumei Tao, Yue Li   +4 more
semanticscholar   +1 more source