Results 221 to 230 of about 1,767,652 (263)

Inhibition mechanism of α-glucosidase inhibitors screened from Tartary buckwheat and synergistic effect with acarbose.

Food Chemistry, 2023
Tartary buckwheat has been shown to provide a good antihyperglycemic effect. However, it is unclear which active compounds play a key role in attenuating postprandial hyperglycemia.
Lin Han, Huiqing Wang, Junwei Cao, Yunlong Li, Xiying Jin, Caian He, Min Wang   +6 more
semanticscholar   +1 more source

Fruit, vegetables, and mushrooms for the preparation of extracts with α-amylase and α-glucosidase inhibition properties: A review.

Food Chemistry, 2021
The inhibition of the α-amylase and α-glucosidase activity facilitates the maintenance of circulating glucose levels by decreasing the rate of blood sugar absorption.
Konstantinos Papoutsis, Jinyuan Zhang, M. Bowyer, N. Brunton, E. Gibney, J. Lyng   +5 more
semanticscholar   +1 more source

Comparison of the generation of α-glucosidase inhibitory peptides derived from prolamins of raw and cooked foxtail millet: In vitro activity, de novo sequencing, and in silico docking.

Food Chemistry, 2023
Foxtail millet prolamin has been demonstrated to have anti-diabetic effects. In this study, we compared the generation of anti-α-glucosidase peptides derived from prolamins of raw and cooked foxtail millet (PRFM and PCFM).
Yongxia Fu, Zhenyu Liu, Han Wang, Fan Zhang, Shang Guo, Q. Shen   +5 more
semanticscholar   +1 more source

A Computational Comparative study of α-Glucosidase enzyme Divergence

Journal of Applied Bioinformatics & Computational Biology, 2015
A Computational Comparative study of α-Glucosidase enzyme Divergence α-Glucosidase (α-Gls) enzymes have a crucial role in digestion of carbohydrates and biosynthesis of glycoproteins. Theses enzymes hydrolyze terminal glycosidic bonds and release α-glucose from the substrate chain. They are found in prokaryotic cells, plants and mammalian tissues such
Mohammad Hossein Mehraban, Younes Ghasemi   +1 more
openaire   +1 more source

Flavonoids as potential agents in the management of type 2 diabetes through the modulation of α-amylase and α-glucosidase activity: a review

Critical reviews in food science and nutrition, 2021
Type 2 diabetes (T2D) is one of the most prevalent metabolic diseases worldwide and is characterized by increased postprandial hyperglycemia (PPHG). α-Amylase and α-glucosidase inhibitors have been shown to slow the release of glucose from starch and ...
C. Proença, D. Ribeiro, M. Freitas, E. Fernandes   +3 more
semanticscholar   +1 more source

Novel bioactive peptides from ginkgo biloba seed protein and evaluation of their α-glucosidase inhibition activity.

Food Chemistry, 2022
The inhibition of α-glucosidase activity has been recognized as an effective approach for treating type 2 diabetes mellitus (T2DM). In recent years, much emphasis has been placed on identifying peptides with α-glucosidase inhibitory activity and ...
Xiang Wang, Yejun Deng, Pujun Xie, Lujie Liu, Caihong Zhang, Jiang Cheng, Yang Zhang, Y. Liu, Lixin Huang, Jianxin Jiang   +9 more
semanticscholar   +1 more source

Effects of hydroxylation at C3' on the B ring and diglycosylation at C3 on the C ring on flavonols inhibition of α-glucosidase activity.

Food Chemistry, 2022
The structure-activity relationship and inhibitory mechanism of flavonols on α-glucosidase were studied by inhibition kinetics, multispectral study, and molecular docking.
Yajuan Qin, Xiaoai Chen, Fei Xu, Chunhe Gu, Kexue Zhu, Yanjun Zhang, Gang Wu, P. Wang, L. Tan   +8 more
semanticscholar   +1 more source

The antioxidant activities, inhibitory effects, kinetics, and mechanisms of artocarpin and α-mangostin on α-glucosidase and α-amylase.

International Journal of Biological Macromolecules, 2022
This study investigated the antioxidant activities, inhibitory activities and the interaction mechanisms of artocarpin and α-mangostin on α-amylase and α-glucosidase.
Qirou Wang, Ruilin Li, Nannan Li, Yanan Jia, Yajie Wang, Yue Chen, P. Panichayupakaranant, Haixia Chen   +7 more
semanticscholar   +1 more source

Metabolite profiling, antioxidant and α-glucosidase inhibitory activities of buckwheat processed by solid-state fermentation with Eurotium cristatum YL-1.

Food Research International, 2021
Buckwheat was processed by solid-state fermentation (SSF) with the probiotic fungal strain Eurotium cristatum YL-1. The effects of SSF on the phytochemical content, as well as the antioxidant and α-glucosidase inhibitory activities, on buckwheat were ...
Yu Xiao, Xing Wu, Xin-Tong Yao, Yulian Chen, Chi-Tang Ho, Cheng-hui He, Zongjun Li, Yuanliang Wang   +7 more
semanticscholar   +1 more source

Chromone-based benzohydrazide derivatives as potential α-glucosidase inhibitor: Synthesis, biological evaluation and molecular docking study.

Bioorganic chemistry (Print), 2022
In order to find new α-glucosidase inhibitors with high efficiency and low toxicity, novel chromone-based benzohydrazide derivatives 6a-6s were synthesized and characterized through 1H NMR, 13C NMR, and HRMS. All the new synthesized compounds were tested
Meiyan Fan, Wei-Qiang Yang, Zhiyun Peng, Yan He, Guangcheng Wang   +4 more
semanticscholar   +1 more source