Results 101 to 110 of about 2,753,652 (191)

Characterization of digestive α- and β-glucosidases in the midgut of Plagiodera versicolora Laicharting (Coleoptera: Chrysomelidae) [PDF]

نامه انجمن حشره‌شناسی ایران, 2016
The imported willow leaf beetle, Plagiodera versicolora is one of the main pests of forest trees worldwide including Iran. Activities of α- and β-glucosidases in the midgut of P. versicolora adults were studied in this research.
M. Shabarari, B. Naseri
doaj  

Inhibitory Mechanism of Taxifolin against α-Glucosidase Based on Spectrofluorimetry and Molecular Docking

Natural Product Communications, 2017
The α-glucosidase inhibitory activity and behavior of taxifolin was first investigated by spectrofluorimetry and molecular docking. It was found that taxifolin inhibits α-glucosidase in a competitive manner with the IC 50 value of 0.16 mg/mL.
Jiang Liu, Xiansheng Wang, Sheng Geng, Benguo Liu, Guizhao Liang   +4 more
doaj   +1 more source

Seasonal activity of neutral α-glucosidase.

, 2015
x—arithmetic mean, SD–standard deviationSeasonal activity of neutral α-glucosidase.
Wojciech Nowacki (805466), Julia Kotońska-Feiga (825007), Przemysław Pokorny (825009), Wojciech Dobicki (825008)   +3 more
core   +1 more source

Rapidly screening of α-glucosidase inhibitors from Dioscorea opposita Thunb. peel based on rGO@Fe3O4 nanocomposites microreactor

Journal of Enzyme Inhibition and Medicinal Chemistry, 2018
Present study aimed to immobilise the α-glucosidase on suitable supports to construct enzymatic microreactors and their subsequent applicability in efficient inhibitor screening from the Chinese Yam (Dioscorea opposita Thunb.) peel.
Songsong Zhang, Beibei Qiu, Jinhua Zhu, Weiping Hu, Fanyi Ma, M. Z. H. Khan, Xiuhua Liu   +6 more
doaj   +1 more source

Benzonate derivatives of acetophenone as potent α-glucosidase inhibitors: synthesis, structure–activity relationship and mechanism

Journal of Enzyme Inhibition and Medicinal Chemistry, 2019
In this article, 23 compounds (6 and 7a–7v) were prepared and evaluated for their in vitro α-glucosidase inhibitory activity. The compounds 7d, 7f, 7i, 7n, 7o, 7r, 7s, 7u, and 7v displayed the α-glucosidase inhibition activity with IC50 values ranging ...
Wen-Jia Dan, Qiang Zhang, Fan Zhang, Wei-Wei Wang, Jin-Ming Gao   +4 more
doaj   +1 more source

Exploring the inhibitory effect and mechanism of 3,4,5-trihydroxybiphenyl on α-glucosidase: an integrated experimental and computational approach

Frontiers in Pharmacology
3,4,5-Trihydroxybiphenyl (THB) is a naturally occurring compound derived from Sorbus pohuashanensis, primarily reported for its antifungal activity. However, its potential to inhibit α-glucosidase remains unclear.
Ruofan Guo, Ruofan Guo, Guohua Yu, Yuan Li, Youyou Wang, Youyou Wang, Huixia Fan, Shuo Zhang, Chen Wang, Junhui Zhou, Junhui Zhou, Jian Yang, Jian Yang, Feng Gao, Feng Gao, Zhiqiang Luo   +15 more
doaj   +1 more source

In Vitro Inhibition of α-Amylase and α-Glucosidase by Different Parts of Amla Plant (Phyllanthus emblica L)

Pharmacology and Clinical Pharmacy Research, 2018
Amla plant (Phyllanthus emblica L) has been empirically used to treat diabetes. The aim of this study was to determine the most potential part of amla plant that can be used as α-glucosidase and α-amylase inhibitors.
Novi I. Fauzi, Maria Ulfah, Syarif Hamdani, Saeful Hidayat   +3 more
doaj  

α-Amylase and α-Glucosidase Inhibition by Brown Seaweed (Sargassum sp) Extracts

, 2014
Inhibition of intestinal α-amylase and α-glucosidase is an important strategy to control post-prandial hyperglycemia associated with diabetes mellitus.
Asep Awaludin Prihanto, Muhammad Firdaus
core   +1 more source

Characterising the selectivity of ER α-glucosidase inhibitors

, 2019
The endoplasmic reticulum (ER) contains both α-glucosidases and α-mannosidases which process the N-linked oligosaccharides of newly synthesised glycoproteins and thereby facilitate polypeptide folding and glycoprotein quality control.
High, Stephen; id_orcid, Roebuck, Quentin P, O'keefe, Sarah, Hirono, Shuichi, Nakagome, Izumi, Nash, Robert, Kato, Atsushi   +6 more
core   +1 more source

Dual-Target Inhibitors against α-Amylase and α-Glucosidase: Novel Anacardic Acid Depside Derivatives

Inhibition of α-amylase and α-glucosidase enzymes are some of the crucial therapeutic targets in diabetes mellitus. The global shift toward sustainable utilization of natural resources has highlighted cashew nut shell liquid (CNSL), a by-product abundant
Kowit Hengphasatporn, Yasuteru Shigeta, Warinthorn Chavasiri, Van-Can Pham   +3 more
core   +1 more source