Results 351 to 360 of about 1,551,967 (375)

Mechanistic insight into the inhibition of α-glucosidase by millet Prolamin K3ZAN2: An integrated experimental and molecular simulation study. [PDF]

Food Chem X
Zhao L, Lin R, Dou X, Zhao Q, Wang C, Xue Y, Shen Q.   +6 more
europepmc   +1 more source

Isolation and characterization of α-glucosidase inhibitors from Phyllanthus acidus (L.) Skeels stem bark

Zeba Siddiqui, Mohammad Irfan Khan, Badruddeen Badruddeen, Mohammad Ahmad Mohammad Ahmad, Manvi Manvi, Gayyur Fatima   +5 more
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α-Glucosidase Inhibition-Guided Network Pharmacology and Molecular Docking Reveal the Antidiabetic Potential of <i>Cichorium intybus</i> as a Functional Food. [PDF]

Int J Mol Sci
Shah AB, Baiseitova A, Amzeyeva U, Shang X, Jenis J.   +4 more
europepmc   +1 more source

Centesimal Composition, Bioactive Compounds, Antioxidant and α-Glucosidase Inhibitory Activities of Commercial Edible Oyster Mushrooms at Different Maturity Stages in Northern Thailand. [PDF]

Foods
Kumla J, Lumyong S, Suwannarach N.
europepmc   +1 more source

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Screening and Evaluation of Novel α-Glucosidase Inhibitory Peptides from Ginkgo biloba Seed Cake Based on Molecular Docking Combined with Molecular Dynamics Simulation.

Journal of Agricultural and Food Chemistry, 2023
Food-derived α-glucosidase inhibitory peptides have gained significant interest in treating type 2 diabetes mellitus (T2DM) owing to their favorable safety profiles.
Xiang Wang, Yejun Deng, Yang Zhang, Caihong Zhang, Lujie Liu, Y. Liu, Jianxin Jiang, Pujun Xie, Lixin Huang   +8 more
semanticscholar   +1 more source

Design and synthesis of 2-amino-4,6-diarylpyrimidine derivatives as potent α-glucosidase and α-amylase inhibitors: structure–activity relationship, in vitro, QSAR, molecular docking, MD simulations and drug-likeness studies

Journal of Biomolecular Structure and Dynamics, 2023
In the present study, a series of 2-amino-4,6-diarylpyrimidine derivatives was designed, synthesized, characterized and evaluated for their in vitro α-glucosidase and α-amylase enzyme inhibition assays.
E. Mughal, Samreen Amjid, A. Sadiq, Nafeesa Naeem, Yasir Nazir, H. A. Alrafai, AbeerHashim Hassan, S. Y. Al-Nami, Amal A. Abdel Hafez, Syed Wadood Ali Shah, Mehreen Ghias   +10 more
semanticscholar   +1 more source

Mechanistic study on the inhibition of α-amylase and α-glucosidase using the extract of ultrasound-treated coffee leaves.

The Journal of the Science of Food and Agriculture, 2023
BACKGROUND Our previous studies have shown that ultrasound-treated γ-aminobutyric acid (GABA)-rich coffee leaves have higher antioxidant and angiotensin I converting enzyme inhibitory activity.
Yu Sun, Qingwei Cao, Yuanyuan Huang, Tingting Lu, Haile Ma, Xiumin Chen   +5 more
semanticscholar   +1 more source

Flavonoids as potential agents in the management of type 2 diabetes through the modulation of α-amylase and α-glucosidase activity: a review

Critical reviews in food science and nutrition, 2021
Type 2 diabetes (T2D) is one of the most prevalent metabolic diseases worldwide and is characterized by increased postprandial hyperglycemia (PPHG). α-Amylase and α-glucosidase inhibitors have been shown to slow the release of glucose from starch and ...
C. Proença, D. Ribeiro, M. Freitas, E. Fernandes   +3 more
semanticscholar   +1 more source

A Computational Comparative study of α-Glucosidase enzyme Divergence

Journal of Applied Bioinformatics & Computational Biology, 2015
A Computational Comparative study of α-Glucosidase enzyme Divergence α-Glucosidase (α-Gls) enzymes have a crucial role in digestion of carbohydrates and biosynthesis of glycoproteins. Theses enzymes hydrolyze terminal glycosidic bonds and release α-glucose from the substrate chain. They are found in prokaryotic cells, plants and mammalian tissues such
Mohammad Hossein Mehraban, Younes Ghasemi   +1 more
openaire   +1 more source

Recent Advances of α-Glucosidase Inhibitors: A Comprehensive Review.

Current Topics in Medicinal Chemistry, 2022
BACKGROUND Diabetes mellitus (DM) is a critical health issue prevailing in nearly half a billion people worldwide. It is one of the most threatening metabolic diseases. Type 2 DM is caused due to insulin resistance and accounts for 90% of diabetes cases.
Ahsas Goyal, N. Agrawal, Manisha Sharma, Shikha Singh   +3 more
semanticscholar   +1 more source