Results 171 to 180 of about 45,106 (236)

Design, synthesis, in vitro α-glucosidase inhibition, docking, and molecular dynamics of new phthalimide-benzenesulfonamide hybrids for targeting type 2 diabetes. [PDF]

Sci Rep, 2022
Askarzadeh M, Azizian H, Adib M, Mohammadi-Khanaposhtani M, Mojtabavi S, Faramarzi MA, Sajjadi-Jazi SM, Larijani B, Hamedifar H, Mahdavi M.   +9 more
europepmc   +1 more source

A Review of Current Computational Tools for Peptide–Protein Docking

Journal of Computational Chemistry, Volume 47, Issue 5, 15 February 2026.
In this review, we compare 14 specialized peptide‐protein docking programs, adaptable small‐molecule docking tools, and emerging AI‐driven approaches. By clarifying how each method works, we offer researchers an accessible guide to selecting the most suitable tools for biochemical studies and peptide‐focused drug discovery.
Fábio G. Martins, Hélder A. Santos, Sérgio F. Sousa   +2 more
wiley   +1 more source

α-Glucosidase Inhibition Mechanism and Anti-Hyperglycemic Effects of Flavonoids from Astragali Radix and Their Mixture Effects. [PDF]

Pharmaceuticals (Basel)
Han X, Wang P, Zhang J, Lv Y, Zhao Z, Zhang F, Shang M, Liu G, Wang X, Cai S, Xu F.   +10 more
europepmc   +1 more source

Novel 5-(Arylideneamino)-1H-Benzo[d]imidazole-2-thiols as Potent Anti-Diabetic Agents: Synthesis, In Vitro α-Glucosidase Inhibition, and Molecular Docking Studies. [PDF]

ACS Omega, 2022
Ali S, Ali M, Khan A, Ullah S, Waqas M, Al-Harrasi A, Latif A, Ahmad M, Saadiq M.   +8 more
europepmc   +1 more source

A general model for analysis of linear and hyperbolic enzyme inhibition mechanisms

FEBS Open Bio, Volume 16, Issue 2, Page 365-381, February 2026.
We developed a general enzyme kinetic model that integrates these six basic inhibition mechanism onto a single one. From this model, we deduced a general enzyme kinetic equation that through modulation of simple parameters, γ (the relative inhibitor affinity for two binding sites) and β (the reactivity of the enzyme–substrate–inhibitor complex), is ...
Rafael S. Chagas, Sandro R. Marana
wiley   +1 more source

Ultrasound-assisted extraction of polyphenols from Lonicera japonica leaves and their α-glucosidase inhibition. [PDF]

Front Nutr
Li G, Bao C, Zhang H, Bai L.
europepmc   +1 more source

Mercaptobenzimidazole-Based 1,3-Thaizolidin-4-ones as Antidiabetic Agents: Synthesis, In Vitro α-Glucosidase Inhibition Activity, and Molecular Docking Studies. [PDF]

ACS Omega, 2022
Khan SA, Ali M, Latif A, Ahmad M, Khan A, Al-Harrasi A.   +5 more
europepmc   +1 more source

Peptide and Drug‐Protected Gold Nanoclusters as Promising Biomaterials: Synthesis, Properties, and Applications

Aggregate, Volume 7, Issue 2, February 2026.
The integration of atomically precise gold nanoclusters with peptides or drugs represents a cutting‐edge class of nanomaterials in the biomedical field, owing to their unique physicochemical properties such as water solubility, excellent biocompatibility, low toxicity, and good renal clearance.
Rebeca Garcia Moura, M. Terêsa Machini, Rongchao Jin   +2 more
wiley   +1 more source

The α-Glucosidase Inhibition Activities of Phaeochromycins D and E Isolated from Marine <i>Streptomyces</i> sp. FJ0218. [PDF]

Molecules
Lin P, Shi M, Wang F, Lin Y, Zheng Y.
europepmc   +1 more source

Inverse Association Between Betel Quid Use and Diabetes in Rural Bangladesh

American Journal of Human Biology, Volume 38, Issue 2, February 2026.
ABSTRACT Objectives Betel quid is used as a mild stimulant in many parts of South and East Asia and the Pacific. In observational studies, its use has been associated with elevated risk for diabetes, but studies in animal models suggest some component(s) of betel quid could reduce risk.
Kristin K. Sznajder, Mary K. Shenk, Laura Perez, Nurul Alam, Rubhana Raqib, Anjan Kumar, Farjana Haque, Tami Blumenfield, Siobhán M. Cully, Katherine Wander   +9 more
wiley   +1 more source