Results 181 to 190 of about 45,106 (236)

In vitro α-Glucosidase Inhibition, Cytotoxicity, SAR, Swiss ADME Prediction and Molecular Docking Study of New N-Substituted Hydantoin Derivatives. [PDF]

ChemistryOpen
Tshiluka NR, Mbedzi DT, Bvumbi MV, Mnyakeni-Moleele SS.   +3 more
europepmc   +1 more source

Risks of dementia and stroke in patients with hypertension using telmisartan or other renin‑angiotensin system inhibitors

Alzheimer's &Dementia, Volume 22, Issue 2, February 2026.
Abstract INTRODUCTION The aim of this study was to investigate the cognitive and cerebrovascular outcomes of patients with hypertension (HTN) receiving various renin‐angiotensin system (RAS) inhibitors. METHODS We further categorized 39,665 patients with HTN receiving long‐term RAS inhibitor therapy into (1) telmisartan, (2) non‐telmisartan angiotensin
Chi‐Hung Liu, Ming‐Lung Tsai, Ning‐I Yang, Ting‐Yu Chang, Tien‐Hsing Chen, Yi‐Chia Wei   +5 more
wiley   +1 more source

Inhibitory Effect and Mechanism of Dancong Tea from Different Harvesting Season on the α-Glucosidase Inhibition In Vivo and In Vitro. [PDF]

Foods
Wen R, Chai X, Wang P, Wu K, Duan X, Chen J, Zhang T, Zeng L.   +7 more
europepmc   +1 more source

Ultrasound-Assisted Extraction of Total Saponins from Aralia taibaiensis: Process Optimization, Phytochemical Characterization, and Mechanism of α-Glucosidase Inhibition. [PDF]

Drug Des Devel Ther, 2022
Li H, Zhai B, Sun J, Fan Y, Zou J, Cheng J, Zhang X, Shi Y, Guo D.   +8 more
europepmc   +1 more source

Development of Peptide Glucosyltransferase Inhibitors With Comprehensive Coverage Across Clostridioides difficile Toxin B Sub‐Types

Biotechnology and Bioengineering, Volume 123, Issue 2, Page 310-323, February 2026.
ABSTRACT Clostridioides difficile infection presents an escalating clinical challenge due to the proliferation of hypervirulent and antibiotic‐resistant strains. The primary symptoms of disease, namely colitis and diarrhea, are induced by the release of two toxins: TcdA and TcdB.
Carly M. Catella, Sudeep Sarma, Caroline M. Hinesley, Corey E. Febo, Keith A. Breau, Deniz Durmusoglu, Ethan Purnell, Scott T. Magness, Carol K. Hall, Stefano Menegatti, Nathan Crook   +10 more
wiley   +1 more source

A Novel In Vivo Method Using Caenorhabditis elegans to Evaluate α-Glucosidase Inhibition by Natural Products for Type 2 Diabetes Treatment. [PDF]

Pharmaceuticals (Basel)
de Torre MP, Vizmanos JL, Cavero RY, Calvo MI.   +3 more
europepmc   +1 more source

The Medicinal Halophyte Frankenia laevis L. (Sea Heath) Has In Vitro Antioxidant Activity, α-Glucosidase Inhibition, and Cytotoxicity towards Hepatocarcinoma Cells. [PDF]

Plants (Basel), 2022
Rodrigues MJ, Jekő J, Cziáky Z, Pereira CG, Custódio L.   +4 more
europepmc   +1 more source

Chemical Profiling, In Silico and In Vitro Studies to Identify Potential CDK2 and mTOR Inhibitor From Selaginella inaequalifolia (Hook. & Grev.) Spring Ethanolic Extracts

Chemistry &Biodiversity, Volume 23, Issue 2, February 2026.
ABSTRACT The current study is aimed to reveal the phytoprofile of Selaginella inaequalifolia (Hook. & Grev.) Spring using GC–MS and predict the drug properties, toxicity, biological properties of S. inaequalifolia ethanolic extracts (SiEE) using in silico methods and in vitro toxicity assays, namely, MTT and BSLB assay.
Johnson Marimuthu Alias Antonysamy, Sivaraman Arumugam, Robin Charles Antony Arulraj, Anne Wincy Jacob Thomas, Henrique D. M. Coutinho   +4 more
wiley   +1 more source

Flavones from <i>Muntingia calabura</i> leaves: structural elucidation and SAR for α-glucosidase inhibition by <i>in vitro</i> and <i>in silico</i> evaluation. [PDF]

RSC Adv
Nguyen HX, Le TM, Le TH, Truong TQ, Nguyen BQH, Nguyen PT, Le KM, Van Do TN, Nguyen MTT, Nguyen MH, Nguyen NT.   +10 more
europepmc   +1 more source

Antioxidant Activity, α-Glucosidase Inhibition and UHPLC-ESI-MS/MS Profile of Shmar (Arbutus pavarii Pamp). [PDF]

Plants (Basel), 2021
Buzgaia N, Lee SY, Rukayadi Y, Abas F, Shaari K.   +4 more
europepmc   +1 more source