Results 21 to 30 of about 45,106 (236)
1,6-Cyclophellitol Cyclosulfates : A New Class of Irreversible Glycosidase Inhibitor [PDF]
, 2017 The essential biological roles played by glycosidases, coupled to the diverse therapeutic benefits of pharmacologically targeting these enzymes, provide considerable motivation for the development of new inhibitor classes.
Aerts, Johannes M.F.G. +12 more
core +17 more sources
MCBS (Molecular and Cellular Biomedical Sciences), 2017 Background: Diabetes mellitus is a metabolic disease, characterized by hyperglycemia due to disturbance in both insulin secretion and function. One of theurapeutic approaches is to reduce blood glucose levels by inhbiting α-/β-glucosidase and α-amylase ...
Marisca Evalina Gondokesumo +2 more
doaj +1 more source
Inhibitory Effect of Naringin on α-Glucosidase and Its Mechanism
Shipin gongye ke-ji, 2022 To investigate the inhibitory activity and mechanism of naringin on α-glucosidase, the inhibition effect, type, and molecular mechanism of naringin on α-glucosidase were investigated by integrative analysis of enzyme kinetics, fluorescence spectroscopy ...
Xiangju ZHOU +6 more
doaj +1 more source
Chemical composition, antioxidant and alpha-Glucosidase-Inhibiting activities of the aqueous and hydroethanolic extracts of Vaccinium myrtillus Leaves [PDF]
, 2017 Vaccinium myrtillus (bilberry) leaf is traditionally used in southeastern Europe for the treatment of diabetes. In the present study, the ability of bilberry leaf extracts to inhibit carbohydrate-hydrolyzing enzymes and restore glutathione concentration ...
Bljajic, Kristina +7 more
core +1 more source
Acantholippia salsoloides : Phytochemical Composition and Biological Potential of a Thujonic Population [PDF]
, 2019 Acantholippia salsoloides (Verbenaceae) is an aromatic plant widespread in the Andean region. The infusion (leaves and flowers) is widely used as a digestive stimulant as well as for the treatment of various diseases in traditional medicine.
Celaya, Liliana Soledad +2 more
core +1 more source
The relevance of α-KLOTHO to the central nervous system: Some key questions [PDF]
, 2017 α-Klotho is well described as an anti-aging protein, with critical roles in kidney function as a transmembrane co-receptor for FGF23, and as a soluble factor in serum.
Berwick, Daniel Charles +4 more
core +1 more source
α-Amylase and α-Glucosidase Inhibition by Brown Seaweed (Sargassum sp) Extracts
Research Journal of Life Science, 2014 Inhibition of intestinal α-amylase and α-glucosidase is an important strategy to control post-prandial hyperglycemia associated with diabetes mellitus.
Muhammad Firdaus, Asep Awaludin Prihanto
doaj +1 more source
Clitoria ternatea L. flower extract inhibits α-amylase during in vitro starch digestion [PDF]
, 2017 This study aimed to investigate the inhibitory effect of Clitoria ternatea flower against α-amylase during simulated in vitro wheat starch digestion. The dark-blue tropical flower is used as a food colorant but its ability to modulate starch digestion ...
Chu, Boon-Seang +3 more
core +1 more source
Journal of Food Quality, 2021 The aim of the current study was to evaluate the interaction effects of myricetrin and dihydromyricetin in inhibiting α-glucosidase and pancreatic lipase at different combination ratios and concentrations and to illuminate the underlying mechanisms of ...
Siyuan Mi +5 more
doaj +1 more source
Foods, 2023 The α-glucosidase inhibitor is of interest to researchers due to its association with type-II diabetes treatment by suppressing postprandial hyperglycemia. Hesperidin is a major flavonoid in orange fruit with diverse biological properties.
Kumaravel Kaliaperumal +6 more
doaj +1 more source