Results 91 to 100 of about 993,255 (173)

α-Mangostin Suppresses TNF-α-Induced Biomarkers of Endothelial Dysfunction

open access: yes
Sepsis is a condition of dysregulated response to infection. Endothelial dysfunction is a key event in the onset and progression of sepsis, marked by a heightened pro-inflammatory response.
Erna-Zulaikha Dayang   +4 more
core   +1 more source

Antimicrobial actions of α-mangostin against oral streptococci

open access: yes, 2011
The increasing prevalence of dental caries is making it more of a major world health problem. Caries is the direct result of acid production by cariogenic oral bacteria, especially Streptococcus mutans . New and better antimicrobial agents active against
Robert E. Marquis, Phuong T. M. Nguyen
core   +1 more source

α-mangostin improves glucose uptake and inhibits adipocytes differentiation in 3T3-L1 cells via PPARgamma, GLUT4, and leptin expressions [PDF]

open access: yes, 2015
Obesity has been often associated with the occurrence of cardiovascular diseases, type 2 diabetes, and cancer. The development of obesity is also accompanied by significant differentiation of preadipocytes into adipocytes.
Deny Susanti,   +10 more
core   +1 more source

Alpha-Mangostin Suppresses the Metastasis of Human Renal Carcinoma Cells by Targeting MEK/ERK Expression and MMP-9 Transcription Activity

open access: yesCellular Physiology and Biochemistry, 2017
Background/Aims: α-mangostin has anti-carcinogenic effects against several cancers. We investigated the molecular mechanism of this compound on the metastasis of human renal carcinoma cells.
Chien-Min Chen   +5 more
doaj   +1 more source

ANTICANCER POTENTIAL OF α-MANGOSTIN

open access: yes, 2017
Objective: Mangosteen (Garcinia mangostana Linn.) is a tropical fruit originated from South East region. Mangosteen exhibiting a variety of pharmacological activities and is often used for traditional medicine.
Cindy Aprillianie Wijaya   +1 more
core   +1 more source

α-mangostin-induced 3T3-L1 preadipocytes apopotosis.

open access: yes, 2013
3T3-L1 preadipocytes were treated with α-mangostin at the indicated concentrations for 24 h. (A) Effect of α-mangostin on cell membrane permeability: original magnification, ×40; exposure times: 20s; (B) Effect of α-mangostin on nuclear chromatin ...
Weixi Tian (329907)   +7 more
core   +1 more source

α-Mangostin extracted from the pericarp of the mangosteen (Garcinia mangostana Linn) reduces tumor growth and lymph node metastasis in an immunocompetent xenograft model of metastatic mammary cancer carrying a p53 mutation

open access: yesBMC Medicine, 2011
Background The mangosteen fruit has a long history of medicinal use in Chinese and Ayurvedic medicine. Recently, the compound α-mangostin, which is isolated from the pericarp of the fruit, was shown to induce cell death in various types of cancer cells ...
Okuno Yasushi   +7 more
doaj   +1 more source

Study on the role of survivin in the anti-melanoma effect of α-mangostin

open access: yes, 2015
人類黑色素癌細胞為皮膚癌中死亡率最高,且近幾十年來全球發生率都逐年上升。儘管早期可透過手術移除有效治療,但晚期治療困難且存活率低。後期以化學治療為主,但化療成效受限於化療藥物抗性及細胞毒性。所以需要更有效的藥新興藥物治療人類黑色素癌細胞。氧雜蒽酮(Xanthone)為天然酚類化合物,此類化合物於山竹(Garcinia mangostana)的果皮含量豐富,亦可於其他植物中發現。文獻指出Xanthone可抑制多種癌細胞生長。 α-山酮素(α-mangostin)為Xanthone中之主要有效成份 ...
Yi-Chun Hung, 洪儀君
core   +1 more source

The Effect of α-Mangostin on TLR-4 and PGE2 in the Dentin-Pulp Complex Exposed to HEMA [PDF]

open access: yes, 2022
Mangosteen is abundant in Indonesia. Most mangosteen pericarp contains Alpha (α) mangostin, which has numerous biological benefits, especially antioxidant, antibacterial and antiinflammatory properties. The purpose of this study is to analyse the effect
Febriastuti Cahyani, -   +9 more
core  

Abstracts

open access: yesMolecular Oncology, Volume 20, Issue S1, Page 1-692, August 2026.
Abstracts submitted to the ‘EACR 2026 Congress: Innovative Cancer Science’, from 08–11 June 2026 and accepted by the Congress Organising Committee are published in this Supplement of Molecular Oncology, an affiliated journal of the European Association for Cancer Research (EACR).
wiley   +1 more source

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