Results 91 to 100 of about 993,255 (173)
α-Mangostin Suppresses TNF-α-Induced Biomarkers of Endothelial Dysfunction
Sepsis is a condition of dysregulated response to infection. Endothelial dysfunction is a key event in the onset and progression of sepsis, marked by a heightened pro-inflammatory response.
Erna-Zulaikha Dayang +4 more
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Antimicrobial actions of α-mangostin against oral streptococci
The increasing prevalence of dental caries is making it more of a major world health problem. Caries is the direct result of acid production by cariogenic oral bacteria, especially Streptococcus mutans . New and better antimicrobial agents active against
Robert E. Marquis, Phuong T. M. Nguyen
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α-mangostin improves glucose uptake and inhibits adipocytes differentiation in 3T3-L1 cells via PPARgamma, GLUT4, and leptin expressions [PDF]
Obesity has been often associated with the occurrence of cardiovascular diseases, type 2 diabetes, and cancer. The development of obesity is also accompanied by significant differentiation of preadipocytes into adipocytes.
Deny Susanti, +10 more
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Background/Aims: α-mangostin has anti-carcinogenic effects against several cancers. We investigated the molecular mechanism of this compound on the metastasis of human renal carcinoma cells.
Chien-Min Chen +5 more
doaj +1 more source
ANTICANCER POTENTIAL OF α-MANGOSTIN
Objective: Mangosteen (Garcinia mangostana Linn.) is a tropical fruit originated from South East region. Mangosteen exhibiting a variety of pharmacological activities and is often used for traditional medicine.
Cindy Aprillianie Wijaya +1 more
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α-mangostin-induced 3T3-L1 preadipocytes apopotosis.
3T3-L1 preadipocytes were treated with α-mangostin at the indicated concentrations for 24 h. (A) Effect of α-mangostin on cell membrane permeability: original magnification, ×40; exposure times: 20s; (B) Effect of α-mangostin on nuclear chromatin ...
Weixi Tian (329907) +7 more
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Background The mangosteen fruit has a long history of medicinal use in Chinese and Ayurvedic medicine. Recently, the compound α-mangostin, which is isolated from the pericarp of the fruit, was shown to induce cell death in various types of cancer cells ...
Okuno Yasushi +7 more
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Study on the role of survivin in the anti-melanoma effect of α-mangostin
人類黑色素癌細胞為皮膚癌中死亡率最高,且近幾十年來全球發生率都逐年上升。儘管早期可透過手術移除有效治療,但晚期治療困難且存活率低。後期以化學治療為主,但化療成效受限於化療藥物抗性及細胞毒性。所以需要更有效的藥新興藥物治療人類黑色素癌細胞。氧雜蒽酮(Xanthone)為天然酚類化合物,此類化合物於山竹(Garcinia mangostana)的果皮含量豐富,亦可於其他植物中發現。文獻指出Xanthone可抑制多種癌細胞生長。 α-山酮素(α-mangostin)為Xanthone中之主要有效成份 ...
Yi-Chun Hung, 洪儀君
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The Effect of α-Mangostin on TLR-4 and PGE2 in the Dentin-Pulp Complex Exposed to HEMA [PDF]
Mangosteen is abundant in Indonesia. Most mangosteen pericarp contains Alpha (α) mangostin, which has numerous biological benefits, especially antioxidant, antibacterial and antiinflammatory properties. The purpose of this study is to analyse the effect
Febriastuti Cahyani, - +9 more
core
Abstracts submitted to the ‘EACR 2026 Congress: Innovative Cancer Science’, from 08–11 June 2026 and accepted by the Congress Organising Committee are published in this Supplement of Molecular Oncology, an affiliated journal of the European Association for Cancer Research (EACR).
wiley +1 more source

