Results 71 to 80 of about 993,255 (173)

α-Mangostin protects against myocardial ischemia reperfusion injury by suppressing the activation of HIF-1α [PDF]

, 2020
Purpose: To investigate the cytoprotective effect of α-mangostin on myocardial tissues in ischemic rats, and the underlying mechanism.Methods: Histopathological changes in myocardial tissues were determined using inverted microscope.
Feng, Manli, Zhu, Dongdong, Wang, Xiaopeng, Yu, Jing, Guo, Wenli, Zhang, Wei, Jiang, Hong, Wang, Xiaoyu, Chen, Yan, Jiao, Yanan, Wang, Chengcheng   +10 more
core   +1 more source

In vitro and in vivo studies reveal α-Mangostin, a xanthonoid from Garcinia mangostana, as a promising natural antiviral compound against chikungunya virus

Virology Journal, 2021
Background Chikungunya virus (CHIKV), a serious health problem in several tropical countries, is the causative agent of chikungunya fever. Approved antiviral therapies or vaccines for the treatment or prevention of CHIKV infections are not available.
Poonam Patil, Megha Agrawal, Shahdab Almelkar, Manish Kumar Jeengar, Ashwini More, Kalichamy Alagarasu, Naveen V. Kumar, Prathama S. Mainkar, Deepti Parashar, Sarah Cherian   +9 more
doaj   +1 more source

A Decade of Green Nanotechnology: Applications, Advances, and Emerging Directions

Advanced Sustainable Systems, Volume 10, Issue 7, July 2026.
Green nanotechnology offers a pathway to more sustainable nanomaterial design by combining renewable sources, safer synthesis methods, and evidence of performance in practical applications. This review highlights progress over the past decade across environmental remediation, agriculture, energy, and biomedicine, while emphasizing that true ...
Shabnam Manafzadeh, Sree Lekshmi Kishore Kumar, Kari Vinzant, Mariya Khodakovskaya   +3 more
wiley   +1 more source

Aktivitas α-glukosidase dari γ-mangostin dan Turunannya pada Kulit Buah Manggis

, 2021
Manggis (Garcinia mangostana Linn) dilaporkan kaya akan turunan senyawa santon teroksigenasi dan terprenilasi, seperti γ-mangostin (1) yang memberikan efek farmakologi antiinflamasi, antikanker, dan antidiabetes.
Rafsanjani, Ega Rocky Maulana
core  

HIGH PERFORMANCE LIQUID CHROMATOGRAPHY METHOD VALIDATION OF α-MANGOSTIN ASSAY IN MANGOSTEEN (Garcinia mangostana L.) FRUIT RIND EXTRACT FORMULATED IN ORAL SOLUTION

Alchemy, 2015
Mangosteen fruit rind extract contain a lot of antioxidants. α-Mangostin is a component in mangosteen fruit rind that has highest antioxidant effect.
Liliek Nurhidayati, Siti Sofiah, Ros Sumarny, Kevin Caesar   +3 more
doaj   +1 more source

Current Perspectives on STING Agonists for Anticancer Drug Development

Chemical Biology &Drug Design, Volume 108, Issue 1, July 2026.
The molecular structures of STING agonists play a decisive role in regulating the STING pathway. Their distinct scaffolds and functional groups orchestrate receptor binding, conformational activation, and the subsequent immune response. ABSTRACT The cyclic GMP‐AMP (cGAS) synthase and stimulator of interferon genes signaling pathway plays a central role
Dilay Kahvecioglu Cicek
wiley   +1 more source

HPLC elution profiles of α-mangostin standard and sample.

, 2016
HPLC elution profiles of α-mangostin standard and sample.
Hongzheng Wang (3094824), Ming Guo (34061), Xiaomeng Wang (348745), Xiaowang Lu (3094827), Peter E. Brodelius (328964)   +4 more
core   +1 more source

Garcinone C Suppresses Cancer Stem Cells and Induces Apoptosis in Triple‐Negative Breast Cancer Through Canonical Wnt Signaling

Food Frontiers, Volume 7, Issue 3, May 2026.
Garcinone C (Gar. C), a xanthone derived from mangosteen (Garcinia mangostana), suppresses triple‐negative breast cancer growth and stemness by inducing mitochondrial‐mediated apoptosis and inhibiting the Wnt/β‐catenin pathway, highlighting its potential as a natural compound for the prevention and treatment TNBC.
Danhong Zheng, Jiazi Chen, Yong Wang, Da Ma, Jing Chen   +4 more
wiley   +1 more source

Impact of Alpha-mangostin on human esophageal adenocarcinoma cells reveals activation of key apoptotic signaling pathways

Discover Oncology
Current chemotherapeutic modalities for the clinical management of esophageal adenocarcinoma, do not, in most cases, result in complete remission and also elicit adverse side effects.
Cecille Canary, Ketki Patil, Vania M. Dominick, Cristina Quintero, Mauricio Rojas, Mitchell Barnes, S. Balakrishna Pai   +6 more
doaj   +1 more source

Targeting Tumor Stroma: Current Challenges and Future Directions

MedComm, Volume 7, Issue 5, May 2026.
Figure 1. Mechanism of ECM reprogramming. Cancer‐associated fibroblasts (CAFs), cancer‐associated macrophages (CAMs), and other mesenchymal cells alter the ECM composition and increase its stiffness by depositing matrix components such as collagen and hyaluronic acid, and secreting cross‐linking agents like lysyl oxidase homolog 2 (LOXL2).
Siwei Wang, Haofan Hu, Weifeng Zeng, Lu Qin, Xiaoping Chen, Zhibin Liao, Furong Liu, Zhanguo Zhang   +7 more
wiley   +1 more source