Results 61 to 70 of about 3,668 (172)

α-Mangostin suppresses 12-o-tetradecanoylphorbol-13- acetate-mediated matrix metalloproteinase-9 expression in human osteosarcoma cells U2OS [PDF]

, 2016
Purpose: To investigate the effect of α-mangostin on matrix metalloproteinase (MMP)-2 and MMP-9 expression in U2OS human osteosarcoma cell lines.Methods: Cytotoxicity of α-mangostin on U2OS cells was determined by MTT assay.
Kaomongkolgit, Ruchadaporn, Yiemwattana, Ichaya   +1 more
core   +2 more sources

Study on Green Extraction Method and the Antioxidant Properties of Xanthones From Mangosteen Pericarp

Journal of Food Processing and Preservation, Volume 2026, Issue 1, 2026.
Xanthones derived from mangosteen pericarp are valuable bioactive compounds; however, conventional extraction methods often depend on organic solvents or exhibit low efficiency. To explore an effective and environmentally sustainable extraction method, medium‐chain triglycerides (MCTs) were adopted as a natural solvent in combination with ultrasonic ...
Hua Liu, Juanjuan Ma, Suhe Xie, Baoyi Ma, Siying Wen, Jinsheng Cui, Yujie Huang, Yihui Huang, Chuting Ou, Shiyi Ou, Essam Hebishy   +10 more
wiley   +1 more source

Anti-α-Glucosidase and Antiglycation Activities of α-Mangostin and New Xanthenone Derivatives: Enzymatic Kinetics and Mechanistic Insights through In Vitro Studies

Molecules, 2022
Diabetes mellitus is characterized by chronic hyperglycemia that promotes ROS formation, causing severe oxidative stress. Furthermore, prolonged hyperglycemia leads to glycation reactions with formation of AGEs that contribute to a chronic inflammatory ...
Francine Medjiofack Djeujo, Valeria Francesconi, Maddalena Gonella, Eugenio Ragazzi, Michele Tonelli, Guglielmina Froldi   +5 more
doaj   +1 more source

Pengujian Aktivitas Antiacne Nanopartikel Kitosan Ekstrak Kulit Buah Manggis (Garcinia Mangostana) [PDF]

, 2014
Uji aktivitas antiacne dari pasta dan bubuk nanopartikel kitosan ekstrak kulit manggis telah diamati terhadap daya hambat pertumbuhan Propionibacterium acnes.
Bunga, O. (Olivia), Kusumaningrum, S. (Susi), Marhamah, M. (Marhamah), Nizar, N. (Nizar), Rismana, E. (Eriawan)   +4 more
core   +1 more source

Identification of Anti‐Inflammatory and Analgesic Mechanisms of Naru‐3 Wei Pill Using Animal Models, UHPLC‐QE‐MS, and Integrated Network Pharmacology

Mediators of Inflammation, Volume 2026, Issue 1, 2026.
Background Naru‐3 Wei Pill is a traditional Mongolian Medicine (TMM) that has anti‐inflammatory, analgesic, and antibacterial effects. The present study aimed to demonstrate the anti‐inflammatory and analgesic effect of Naru‐3 Wei Pill, identify the core components and key targets and determine the pharmacological basis and mechanism of its blood‐borne
Zhiqiang Han, Husile Kang, Aidi Zhang, Qigeqin, Baolechaolu, Wulanqiqige, Huan Wang, Yanhua Xu, HaSi, Anda, Lan Xue, K. Sony Reddy   +11 more
wiley   +1 more source

Inhibitory Effect of Alpha-Mangostin to Dengue Virus Replication and Cytokines Expression in Human Peripheral Blood Mononuclear Cells

Natural Products and Bioprospecting, 2019
Massive pro-inflammatory cytokines production has been correlated with the pathogenesis of severe dengue disease. The active compound of mangosteen fruit pericarps, α-mangostin, has been commonly used as traditional medicine and dietary supplement.
Zaenal Sugiyanto, Benediktus Yohan, Soeharyo Hadisaputro, Edi Dharmana, Catharina Suharti, Winarto, Kis Djamiatun, Fifin L. Rahmi, R. Tedjo Sasmono   +8 more
doaj   +1 more source

Santon Diprenilasi dari Kayu Akar Garcinia Tetranda Pierre [PDF]

, 2015
Garcinia tetranda merupakan salah satu spesies dari famili Clusiaceae yang mengandung senyawa metabolit sekunder. Senyawa golongan santon telah berhasil diisolasi dari fraksi S ekstrak etil asetat kayu akar Garcinia tetranda Pierre.
Ersam, T. (Taslim), Kharomah, F. R. (Fuji)   +1 more
core  

Exploring gastroprotective effect and mechanisms of epigallocatechin gallate‐impregnated black garlic in acidic ethanol‐induced gastric ulcer model mice

Journal of the Science of Food and Agriculture, Volume 105, Issue 15, Page 8717-8732, December 2025.
Abstract Background Peptic ulcers, particularly gastric ulcers (GUs), are multifactorial disorders with unclear mechanisms. Black garlic (BG) has shown gastroprotective effects. This study evaluated the effects of BG and epigallocatechin gallate‐impregnated BG (EG) in acidic ethanol (AE)‐induced GU model mice. Mice were pretreated with BG or EG (50–200 
Ming‐Shiun Tsai, Gunn‐Guang Liou, Chang‐Wei Hsieh, Jiunn‐Wang Liao, Pin‐Yen Lai, Chao‐Kai Chang, Wan‐Jou Lee, Sue‐Hong Wang   +7 more
wiley   +1 more source

The α-mangostin effect on the quantity of TGF-β1 titer relate to the mandibular bone volume of Rattus novergicus in the periodontitis model [PDF]

Journal of Pharmacy & Pharmacognosy Research, 2021
Context: Periodontitis causes pocket formation, gingival recession, and destruction of periodontal ligaments and alveolar bone. Periodontitis disturbs the attachment of periodontal ligaments to the maxillary and mandibular bones.
Citra Lestari, Eryati Darwin, Deddi Prima Putra, Netti Suharti   +3 more
doaj  

In vitro and in vivo studies reveal α-Mangostin, a xanthonoid from Garcinia mangostana, as a promising natural antiviral compound against chikungunya virus

Virology Journal, 2021
Background Chikungunya virus (CHIKV), a serious health problem in several tropical countries, is the causative agent of chikungunya fever. Approved antiviral therapies or vaccines for the treatment or prevention of CHIKV infections are not available.
Poonam Patil, Megha Agrawal, Shahdab Almelkar, Manish Kumar Jeengar, Ashwini More, Kalichamy Alagarasu, Naveen V. Kumar, Prathama S. Mainkar, Deepti Parashar, Sarah Cherian   +9 more
doaj   +1 more source