Results 61 to 70 of about 993,255 (173)

Inhibitory effects of α-mangostin on FAS activities.

, 2013
(A) and (B) Lineweaver-Burk plots for inhibition of FAS overall reaction: (A) Acetyl-CoA was the variable substrate. The concentrations of α-mangostin were 0 µM (⧫); 5 µM (•); 10 µM (▴); 15 µM (+). (B) Malonyl-CoA was the variable substrate.
Weixi Tian (329907), Xiaofeng Ma (329904), Hezhong Jiang (329910), Youxing Zhao (329911), Yan Liang (139654), Xiaofang Quan (329902), Yi Wang (32470), Qingyun Ma (329909)   +7 more
core   +1 more source

Inhibitory Effect of Alpha-Mangostin to Dengue Virus Replication and Cytokines Expression in Human Peripheral Blood Mononuclear Cells

Natural Products and Bioprospecting, 2019
Massive pro-inflammatory cytokines production has been correlated with the pathogenesis of severe dengue disease. The active compound of mangosteen fruit pericarps, α-mangostin, has been commonly used as traditional medicine and dietary supplement.
Zaenal Sugiyanto, Benediktus Yohan, Soeharyo Hadisaputro, Edi Dharmana, Catharina Suharti, Winarto, Kis Djamiatun, Fifin L. Rahmi, R. Tedjo Sasmono   +8 more
doaj   +1 more source

Nanopolyphenol rejuvenates microglial surveillance of multiple misfolded proteins through metabolic reprogramming

Acta Pharmaceutica Sinica B, 2023
Microglial surveillance plays an essential role in clearing misfolded proteins such as amyloid-beta, tau, and α-synuclein aggregates in neurodegenerative diseases.
Dayuan Wang, Xiao Gu, Xinyi Ma, Jun Chen, Qizhi Zhang, Zhihua Yu, Juan Li, Meng Hu, Xiaofang Tan, Yuyun Tang, Jianrong Xu, Minjun Xu, Qingxiang Song, Huahua Song, Gan Jiang, Zaiming Tang, Xiaoling Gao, Hongzhuan Chen   +17 more
doaj   +1 more source

Feature Cover: Free Phenolic Hydroxyl Groups Govern the Anticancer Activity of α‐Mangostin: A Structure–Activity Relationship Insight

ChemFoodChem, Volume 2, Issue 3, September 2026.
The xanthone mangostin (MGT) isolated from the pericarp of mangosteen fruit (Garcinia mangostana Linn.) presented an anticancer profile against murine colon cancer (CT26), murine triple‐negative breast cancer (4T1), and human osteosarcoma cancer (U2OS).
Otávio Augusto Chaves, Afonso Santine M. M. Velez, Lívia Stenico, Douglas Chaves de Alcântara Pinto, Debora Decote‐Ricardo, Eliezer Avila Gandra, Marco Edilson Freire de Lima, Carlos Serpa   +7 more
wiley   +1 more source

The binding constant of α-mangostin binding with HSA/TRF.

, 2016
The binding constant of α-mangostin binding with HSA/TRF.
Hongzheng Wang (3094824), Ming Guo (34061), Xiaomeng Wang (348745), Xiaowang Lu (3094827), Peter E. Brodelius (328964)   +4 more
core   +1 more source

Dietary α‐Mangostin Alleviates Steatotic Liver Phenotypes by Remodeling Gut Microbial Tryptophan Metabolism

Food Frontiers, Volume 7, Issue 5, September 2026.
ABSTRACT α‐Mangostin (α‐MA), the major xanthone in mangosteen pericarp, is a food‐derived bioactive compound with potential metabolic benefits. However, whether its beneficial effects are linked to gut microbial metabolism remains unclear. In this study, α‐MA was first chemically characterized and subsequently evaluated in an aged laying hen model ...
Weichen Huang, Yujie Lv, Chaoyue Ge, Shenao Zhan, Xinyu Shen, Lianchi Wu, Xiaoxu Wang, Hongmeng Yuan, Dongyou Yu, Bing Liu   +9 more
wiley   +1 more source

The results of UV spectra of α-mangostin.

, 2016
The results of UV spectra of α-mangostin.
Hongzheng Wang (3094824), Ming Guo (34061), Xiaomeng Wang (348745), Xiaowang Lu (3094827), Peter E. Brodelius (328964)   +4 more
core   +1 more source

The α-mangostin effect on the quantity of TGF-β1 titer relate to the mandibular bone volume of Rattus novergicus in the periodontitis model [PDF]

Journal of Pharmacy & Pharmacognosy Research, 2021
Context: Periodontitis causes pocket formation, gingival recession, and destruction of periodontal ligaments and alveolar bone. Periodontitis disturbs the attachment of periodontal ligaments to the maxillary and mandibular bones.
Citra Lestari, Eryati Darwin, Deddi Prima Putra, Netti Suharti   +3 more
doaj  

Chemical Composition and Biological Activities of Geopropolis From Four Melipona Species From the Brazilian Atlantic Forest

Chemistry &Biodiversity, Volume 23, Issue 8, August 2026.
Geopropolis from four Melipona species collected in the Brazilian Atlantic Forest during the dry and rainy seasons was chemically characterized by ESI(‐)‐FT‐ICR MS and evaluated for antioxidant, anti‐inflammatory, and antifungal activities, demonstrating species‐ and season‐dependent variation in its chemical composition and biological properties ...
Ariane Pinheiro Cruz Bergamini, Antônio Domingos de Sousa Júnior, Flavia Vitorino de Araújo Porto, Iana Soares Pessoa, Thiago Antonio de Sousa Cutrim, Victor Paulo Mesquita Aragão, Victor da Rocha Fonseca, Wanderson Romão, Denise Coutinho Endringer, Rodrigo Scherer, Marcio Fronza   +10 more
wiley   +1 more source

The thermodynamic parameters of α-mangostin binding with HSA/TRF.

, 2016
The thermodynamic parameters of α-mangostin binding with HSA/TRF.
Hongzheng Wang (3094824), Ming Guo (34061), Xiaomeng Wang (348745), Xiaowang Lu (3094827), Peter E. Brodelius (328964)   +4 more
core   +1 more source