Results 41 to 50 of about 1,910 (128)

Penambatan Molekuler α, β, dan γ-mangostin Sebagai Inhibitor α-amilase Pankreas Manusia

Indonesian Journal of Chemical Research, 2019
In silico studies on interactions between the human pancreatic α-amylase (HPA) enzyme with α, β, and γ-mangostin ligands has been carried out using the molecular docking method. Ligands α, β, and γ-mangostin interact through the formation of hydrogen and
Nelson Gaspersz, Mario Rowan Sohilait
doaj   +1 more source

Engineering Tertiary Lymphoid Structures: Nanomedicine, Bioengineering, and Biomaterials for Precision Immunotherapy

Advanced NanoBiomed Research, Volume 6, Issue 4, April 2026.
This review explains how biomaterials and nanoparticles can be used to induce or modulate tertiary lymphoid structures (TLSs), which are ectopic immune hubs that form in nonlymphoid tissues during chronic disease and cancer. By comparing different methods, the article highlights design principles for modeling TLSs or recapitulating specific TLS ...
Shaza Karaman, Mei ElGindi, Jeremy Teo
wiley   +1 more source

Immunomodulatory Activities of α-Mangostin on Peripheral Blood Mononuclear Cells

Natural Product Communications, 2013
Mangosteen ( Garcinia mangostana L.) a tropical fruit, has been used in traditional medicine. A frequently used part of mangosteen is the pericarp, containing a high content of xanthones.
Pimolkan Kasemwattanaroj, Primchanien Moongkarndi, Kovit Pattanapanyasat, Supachoke Mangmool, Ekkarat Rodpai, Jutima Samer, Julaporn Konlata, Kasama Sukapirom   +7 more
doaj   +1 more source

A Narrative Review on Unravelling Bacterial‐Mediated Carcinogenesis and Possible Alternative Treatment Strategies

BioMed Research International, Volume 2026, Issue 1, 2026.
The potential roles of chemical, physical, and viral factors in cancer development are well documented. Similarly, bacterial carcinogenesis has been reported previously, though not extensively. Therefore, we aimed to provide comprehensive, mechanistic evidence on the pathogenesis of bacteria‐induced carcinogenesis and possible treatments to halt cancer
Md Sohel, Suraiya Aktar, Sanzida Khatun, Sherif Hamidu, Nishat Ulfat Nity, Sandeep Kumar, Md Sakhawat Hossain, Md. Rifat Sarker, Snygdha Rani Das, Badhan Rani Dey, Ali Mohamod Wasaf Hasan, Khairul Islam, Farhadul Islam, Abdullah Al Mamun, Baisakhi Banerjee   +14 more
wiley   +1 more source

Herbal Cocktail Hydrogel Film (Garcinia mangostana, Centella asiatica, and Chromolaena odorata Extracts): A Novel Wound Dressing Approach

International Journal of Biomaterials, Volume 2026, Issue 1, 2026.
Chronic and infected wounds remain a significant clinical challenge due to delayed healing and the risk of microbial contamination. Conventional wound dressings often fail to provide comprehensive therapeutic support, necessitating the development of advanced multifunctional materials.
Tanikan Sangnim, Chonlada Panpipat, Suwisit Manmuan, Nontanat Leehueng, Wasutthanat Suphan, Chanapa Thuenaram, Kampanart Huanbutta, Srijoni Sengupta   +7 more
wiley   +1 more source

Advancements in Alginate‐Based Biomaterials for Enhanced Skin Regeneration: A Comprehensive Review

International Journal of Polymer Science, Volume 2026, Issue 1, 2026.
Alginate, a naturally occurring polysaccharide composed of β‐d‐mannuronate (M) and α‐l‐guluronate (G), has attracted widespread attention for skin regeneration applications due to its exceptional biocompatibility, biodegradability, and tunable physicochemical properties. Beyond its traditional role in maintaining a moist wound environment and providing
Nasrul Wathoni, Anita Salsabila Herginto, Cecep Suhandi, Khaled M. Elamin, Ahmed Fouad Abdelwahab Mohammed, Safwat A. Mahmoud, Raden M. Febriyanti, Gofarana Wilar, Yihu Song   +8 more
wiley   +1 more source

Comparative Assessment of the Therapeutic Effects of Ethanolic Extracts From Dragon Fruit and Mangosteen on Cadmium‐Induced Hepatotoxicity in Rats

Journal of Food Biochemistry, Volume 2026, Issue 1, 2026.
Introduction Because of its incredibly long half‐life in the body, cadmium (Cd) is a powerful toxicant that poses a risk to the environment and workers. Even modest exposure levels to Cd can cause severe oxidative stress in the liver and other organs.
Lashin S. Ali, Hoda A. Fansa, Maha A. Aljumaa, Dalal S. Alshaya, Manal Almatrafi, Khalid M. Alsyaad, Ehab I. El-Hallous, Fawziah A. Al-Salmi, Tamer M. Shawky, Nermine Beshara, Mohamed G. Shalan, Eman Fayad, Mamdouh Eldesoqui, Dlovan Y. Khalil, Rozhan Yassin Khalil, Ibrahim Youssef, Shady G. El-Sawah, Anupama Bose   +17 more
wiley   +1 more source

Alpha-mangostin, piperine and beta-sitosterol as hepatitis C antivirus (HCV): In silico and in vitro studies

Heliyon, 2023
Hepatitis C is still a serious liver case of health. Up to now the development of anti-Hepatitis C Virus (HCV) drugs is challenging, especially the development of natural material compounds as anti-HCV.
Anjar Hermadi Saputro, Tasia Amelia, Andhika Bintang Mahardhika, Aty Widyawaruyanti, Tutik Sri Wahyuni, Adita Ayu Permanasari, Aluicia Anita Artarini, Daryono Hadi Tjahjono, Sophi Damayanti   +8 more
doaj   +1 more source

Study on Green Extraction Method and the Antioxidant Properties of Xanthones From Mangosteen Pericarp

Journal of Food Processing and Preservation, Volume 2026, Issue 1, 2026.
Xanthones derived from mangosteen pericarp are valuable bioactive compounds; however, conventional extraction methods often depend on organic solvents or exhibit low efficiency. To explore an effective and environmentally sustainable extraction method, medium‐chain triglycerides (MCTs) were adopted as a natural solvent in combination with ultrasonic ...
Hua Liu, Juanjuan Ma, Suhe Xie, Baoyi Ma, Siying Wen, Jinsheng Cui, Yujie Huang, Yihui Huang, Chuting Ou, Shiyi Ou, Essam Hebishy   +10 more
wiley   +1 more source

Nanopolyphenol rejuvenates microglial surveillance of multiple misfolded proteins through metabolic reprogramming

Acta Pharmaceutica Sinica B, 2023
Microglial surveillance plays an essential role in clearing misfolded proteins such as amyloid-beta, tau, and α-synuclein aggregates in neurodegenerative diseases.
Dayuan Wang, Xiao Gu, Xinyi Ma, Jun Chen, Qizhi Zhang, Zhihua Yu, Juan Li, Meng Hu, Xiaofang Tan, Yuyun Tang, Jianrong Xu, Minjun Xu, Qingxiang Song, Huahua Song, Gan Jiang, Zaiming Tang, Xiaoling Gao, Hongzhuan Chen   +17 more
doaj   +1 more source