Results 41 to 50 of about 3,668 (172)

Garcinone C Suppresses Cancer Stem Cells and Induces Apoptosis in Triple‐Negative Breast Cancer Through Canonical Wnt Signaling

Food Frontiers, Volume 7, Issue 3, May 2026.
Garcinone C (Gar. C), a xanthone derived from mangosteen (Garcinia mangostana), suppresses triple‐negative breast cancer growth and stemness by inducing mitochondrial‐mediated apoptosis and inhibiting the Wnt/β‐catenin pathway, highlighting its potential as a natural compound for the prevention and treatment TNBC.
Danhong Zheng, Jiazi Chen, Yong Wang, Da Ma, Jing Chen   +4 more
wiley   +1 more source

Penambatan Molekuler α, β, dan γ-mangostin Sebagai Inhibitor α-amilase Pankreas Manusia

Indonesian Journal of Chemical Research, 2019
In silico studies on interactions between the human pancreatic α-amylase (HPA) enzyme with α, β, and γ-mangostin ligands has been carried out using the molecular docking method. Ligands α, β, and γ-mangostin interact through the formation of hydrogen and
Nelson Gaspersz, Mario Rowan Sohilait
doaj   +1 more source

UJI AKTIVITAS ANTIJAMUR α-MANGOSTIN HASIL ISOLASI KULIT BUAH MANGGIS (Garcinia mangsatana L.) TERHADAP JAMUR DERMATOFIT Trichophyton rubrum [PDF]

, 2010
Salah satu bahan yang dapat dimanfaatkan sebagai obat alam adalah manggis (Garcinia mangostana L.) yang diambil bagian kulitnya karena banyak mengandung senyawa α-mangostin.
WIDIARTI , ENDAH
core  

Targeting Tumor Stroma: Current Challenges and Future Directions

MedComm, Volume 7, Issue 5, May 2026.
Figure 1. Mechanism of ECM reprogramming. Cancer‐associated fibroblasts (CAFs), cancer‐associated macrophages (CAMs), and other mesenchymal cells alter the ECM composition and increase its stiffness by depositing matrix components such as collagen and hyaluronic acid, and secreting cross‐linking agents like lysyl oxidase homolog 2 (LOXL2).
Siwei Wang, Haofan Hu, Weifeng Zeng, Lu Qin, Xiaoping Chen, Zhibin Liao, Furong Liu, Zhanguo Zhang   +7 more
wiley   +1 more source

Immunomodulatory Activities of α-Mangostin on Peripheral Blood Mononuclear Cells

Natural Product Communications, 2013
Mangosteen ( Garcinia mangostana L.) a tropical fruit, has been used in traditional medicine. A frequently used part of mangosteen is the pericarp, containing a high content of xanthones.
Pimolkan Kasemwattanaroj, Primchanien Moongkarndi, Kovit Pattanapanyasat, Supachoke Mangmool, Ekkarat Rodpai, Jutima Samer, Julaporn Konlata, Kasama Sukapirom   +7 more
doaj   +1 more source

Synthesis of toxyloxanthone B [PDF]

, 2014
A synthesis of the naturally occurring xanthone toxyloxanthone B is described, in which the key step is the regioselective addition of a methyl salicylate to a substituted benzyne followed by cyclization of the intermediate aryl anion to form the ...
Giallombardoa, Daniele, Kitson, Russell R.A., Lewis, William, Moody, Christopher J., Nawrat, Christopher C., Nevin, Adam C.   +5 more
core   +3 more sources

Engineering Tertiary Lymphoid Structures: Nanomedicine, Bioengineering, and Biomaterials for Precision Immunotherapy

Advanced NanoBiomed Research, Volume 6, Issue 4, April 2026.
This review explains how biomaterials and nanoparticles can be used to induce or modulate tertiary lymphoid structures (TLSs), which are ectopic immune hubs that form in nonlymphoid tissues during chronic disease and cancer. By comparing different methods, the article highlights design principles for modeling TLSs or recapitulating specific TLS ...
Shaza Karaman, Mei ElGindi, Jeremy Teo
wiley   +1 more source

EFEKTIVITAS EKSTRAK KULIT MANGGIS(Garcinia mangostana) TERHADAP JUMLAH LIMFOSIT T CD4+ DAN KADAR IL-2 PADA PENDERITA HIV DENGAN TERAPI ANTIRETROVIRAL [PDF]

, 2015
Background : HIV attacks human’s CD4+ T lymphocytes immunity system. IL-2 initiate cell cycle progression and CD4 T Lymphocytes proliferation. IL-2 becoming Indicator of immunity system repair within HIV infection2. HIV patients under ARV medication with
Amanah, Amanah
core  

A Narrative Review on Unravelling Bacterial‐Mediated Carcinogenesis and Possible Alternative Treatment Strategies

BioMed Research International, Volume 2026, Issue 1, 2026.
The potential roles of chemical, physical, and viral factors in cancer development are well documented. Similarly, bacterial carcinogenesis has been reported previously, though not extensively. Therefore, we aimed to provide comprehensive, mechanistic evidence on the pathogenesis of bacteria‐induced carcinogenesis and possible treatments to halt cancer
Md Sohel, Suraiya Aktar, Sanzida Khatun, Sherif Hamidu, Nishat Ulfat Nity, Sandeep Kumar, Md Sakhawat Hossain, Md. Rifat Sarker, Snygdha Rani Das, Badhan Rani Dey, Ali Mohamod Wasaf Hasan, Khairul Islam, Farhadul Islam, Abdullah Al Mamun, Baisakhi Banerjee   +14 more
wiley   +1 more source

PENGARUH PEMBERIAN SENYAWA ALFA MANGOSTIN TERHADAP KADAR KOLESTEROL-LDL PADA Rattus novergicus TERINDUKSI DIABETES MELITUS [PDF]

, 2017
Garcinia mangostana L. merupakan nama latin dari tanaman manggis yang berasal dari hutan tropis di kawasan Asia Tenggara yaitu Malaysia dan Indonesia. Salah satu kandungan dari manggis adalah xanthone yang memiliki aktifitas antioksidan.
AFIFAH, ERLY ROIFATUL
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