Results 31 to 40 of about 993,255 (173)
Journal of Advanced Pharmaceutical Technology & Research, 2021 α-mangostin, γ-mangostin, and xanthone are some of the marker compounds found in mangosteen (Garcinia mangostana Linn.) whose activity on several treatment targets including toward the peroxisome proliferator-activated receptor gamma (PPAR-γ) receptors ...
Rifa'atul Mahmudah +2 more
doaj +1 more source
Viability of α-mangostin and Lipopolysaccharide (LPS) in 7F2 Cells [PDF]
, 2023 Based on data from RISKESDAS in 2018, the incidence of tooth extraction in Indonesia is 19%. In post-extraction of teeth, the gingival tissue around the extraction area is inflamed as well as a decrease in the dimensions of the alveolar ridge.
Retno Widyowati, - +4 more
core +1 more source
In Vitro Permeation and Skin Retention of α-Mangostin Proniosome [PDF]
, 2016 The current investigation evaluated the potential of proniosome as a carrier to enhance skin permeation and skin retention of a highly lipophilic compound, α-mangostin. α-Mangostin proniosomes were prepared using the coacervation phase seperation method.
杉林, 堅次 +4 more
core +1 more source
Jurnal Farmasi dan Ilmu Kefarmasian Indonesia, 2021 Background: Diabetes Mellitus (DM) is a complex chronic disease characterized by increased blood glucose. The incidence of this disease is rising, especially type 2 diabetes which is caused by insulin resistance in the body.
Intan Kris Prasetyanti +2 more
doaj +1 more source
Honokiol and Alpha-Mangostin Inhibit Mayaro Virus Replication through Different Mechanisms
Molecules, 2022 Mayaro virus (MAYV) is an emerging arbovirus with an increasing circulation across the Americas. In the present study, we evaluated the potential antiviral activity of the following natural compounds against MAYV and other arboviruses: Sanguinarine, (R ...
Patricia Valdés-Torres +5 more
doaj +1 more source
Journal of Advanced Pharmaceutical Technology & Research, 2021 The study aimed to investigate the interaction of host-guest between α-mangostin and β-cyclodextrin (βCD) and also to calculate the energy of the complex system between α-mangostin with βCD for drug delivery using methods of 15 molecular dynamics and ...
Dian Triwahyuningtyas +4 more
doaj +1 more source
α-Mangostin Induces Ca2+-ATPase-Dependent Apoptosis via Mitochondrial Pathway in PC12 Cells
Journal of Pharmacological Sciences, 2004 We investigated the cell death effects of eight xanthones on PC12 rat pheochromocytoma cells. Among these compounds, α-mangostin, from the fruit hull of Garcinia mangostana L., had the most potent effect with the EC50 value of 4 μM.
Ayumi Sato +4 more
doaj +1 more source
Dose-Independent ADME Properties and Tentative Identification of Metabolites of α-Mangostin from Garcinia mangostana in Mice by Automated Microsampling and UPLC-MS/MS Methods. [PDF]
PLoS ONE, 2015 The information about a marker compound's pharmacokinetics in herbal products including the characteristics of absorption, distribution, metabolism, excretion (ADME) is closely related to the efficacy/toxicity.
Seung Yon Han +4 more
doaj +1 more source
KARAKTERISASI SUSPENSI NANOPARTIKEL α-MANGOSTIN BERBASIS KITOSAN SEBAGAI SISTEM PENGHANTAR OBAT
Parapemikir : Jurnal Ilmiah Farmasiα-Mangostin (αM) merupakan senyawa xanton bioaktif utama yang berasal dari Garcinia mangostana L. dan diketahui memiliki berbagai aktivitas farmakologis, seperti antioksidan, antiinflamasi, dan antimikroba. Namun, pemanfaatan αM secara topikal maupun oral masih terbatas akibat ketidakstabilan dan kelarutannya yang rendah dalam media berair, sehingga
Kusnadi Kusnadi, Muladi Putra Mahardika
openaire +1 more source
Phytomedicine Plus, 2022 Background: : The extracts of Garcinia mangostana (L) pericarp contain high concentration of prenylated xanthones such as α-, β- and γ-mangostin and related molecules.
Swathy Unnikrishna Pillai Saraswathy +6 more
doaj +1 more source