Dose-Independent ADME Properties and Tentative Identification of Metabolites of α-Mangostin from Garcinia mangostana in Mice by Automated Microsampling and UPLC-MS/MS Methods. [PDF]
PLoS ONE, 2015 The information about a marker compound's pharmacokinetics in herbal products including the characteristics of absorption, distribution, metabolism, excretion (ADME) is closely related to the efficacy/toxicity.
Seung Yon Han +4 more
doaj +1 more source
Journal of Advanced Pharmaceutical Technology & Research, 2021 The study aimed to investigate the interaction of host-guest between α-mangostin and β-cyclodextrin (βCD) and also to calculate the energy of the complex system between α-mangostin with βCD for drug delivery using methods of 15 molecular dynamics and ...
Dian Triwahyuningtyas +4 more
doaj +1 more source
Cytotoxicity and structure-activity relationships of xanthone derivatives from Mesua beccariana, Mesua ferrea and Mesua congestiflora towards nine human cancer cell lines. [PDF]
, 2013 The cytotoxic structure-activity relationships among a series of xanthone derivatives from Mesua beccariana, Mesua ferrea and Mesua congestiflora were studied. Eleven xanthone derivatives identified as mesuarianone (1), mesuasinone (2), mesuaferrin A (3),
Gwendoline Cheng +5 more
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Potency of Xanthone Derivatives as Antibacterial Agent Against Methicillin-Resistant Staphylococcus Aureus (MRSA) [PDF]
, 2017 Antibiotic resistance is increasing worldwide and becoming a serious problem for the treatment of patients and also affecting their economy. One instance of bacteria that is resistant to the antibiotic is Methicillin- Resistant Staphylococcus aureus ...
Miladiyah, I. (Isnatin) +1 more
core +2 more sources
Phytomedicine Plus, 2022 Background: : The extracts of Garcinia mangostana (L) pericarp contain high concentration of prenylated xanthones such as α-, β- and γ-mangostin and related molecules.
Swathy Unnikrishna Pillai Saraswathy +6 more
doaj +1 more source
Antibiotics, 2022 This systematic review aims to evaluate the antimicrobial activity of α-mangostin derived from Garcinia mangostana against different microbes. A literature search was performed using PubMed and Science Direct until March 2022.
Omer Sheriff Sultan +9 more
doaj +1 more source
Supplementation with a Polyphenol-Rich Extract, TensLess® , Attenuates Delayed Onset Muscle Soreness and Improves Muscle Recovery from Damages After Eccentric Exercise. [PDF]
, 2017 High-intensity exercises are known to provoke delayed onset muscle soreness (DOMS). Delayed onset muscle soreness typically occurs within the first 24 h, peaks between 24 and 72 h, and can last as long as 5-7 days post-exercise.
Alcaraz Ramón, Pedro Emilio +7 more
core +2 more sources
Polish Journal of Microbiology, 2023 Alpha-mangostin (α-mangostin) was discovered as a potent natural product against Gram-positive bacteria, whereas the underlying molecular mechanisms are still unclear.
Deng Xiangbin +8 more
doaj +1 more source
PENETAPAN KADAR SENYAWA α-MANGOSTIN PADA SEDIAAN DECOCTA KULIT BUAH MANGGIS (Garcinia mangostana L.) [PDF]
, 2010 Kulit buah manggis (Garcinia mangostana L.) dapat dimanfaatkan dalam sediaan herbal berupa decocta. Kandungan utama senyawa aktif pada kulit buah manggis adalah α-mangostin. Penelitian ini bertujuan untuk mengetahui kadar senyawa α-mangostin pada sediaan
PURWATI , ANNY
core
Inhibition of cell proliferation, migration and invasion of B16-F10 melanoma cells by α-mangostin [PDF]
, 2014 In this study, we have evaluated the potential antineoplastic effects of α-mangostin (α-M), the most representative xanthone in Garcinia mangostana pericarp, on melanoma cell lines. This xanthone markedly inhibits the proliferation of high-metastatic B16-
Beninati, S +8 more
core +2 more sources