Results 21 to 30 of about 1,910 (128)
α-Mangostin Extraction from the Native Mangosteen (Garcinia mangostana L.) and the Binding Mechanisms of α-Mangostin to HSA or TRF. [PDF]
PLoS ONE, 2016 In order to obtain the biological active compound, α-mangostin, from the traditional native mangosteen (Garcinia mangostana L.), an extraction method for industrial application was explored.
Ming Guo +4 more
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Journal of Advanced Pharmaceutical Technology & Research, 2021 α-mangostin is a xanthone compound isolated from mangosteen pericarp. It is known as an anticancer through induction of apoptotic process by inhibiting fatty acid synthase (FAS) receptor. α-mangostin is a potentially useful ligand for diagnostic purposes
N Elly Rosilawati +4 more
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Inhibitory effects of α-Mangostin on T cell cytokine secretion via ORAI1 calcium channel and K+ channels inhibition [PDF]
PeerJ, 2021 Background As one of the main components of mangosteen (Garcinia mangostana), a tropical fruit, α-mangostin has been reported to have numerous pharmacological benefits such as anti-cancer, anti-inflammatory, and anti-allergic effects through various ...
Hyun Jong Kim +7 more
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The Scientific World Journal, 2022 Alpha-mangostin, a natural xanthone mainly extracted from the pericarp of Garcinia mangostana, has been shown to have promising anticancer properties in many types of cancer.
Intouch Sakpakdeejaroen +3 more
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α-Mangostin induces apoptosis and suppresses differentiation of 3T3-L1 cells via inhibiting fatty acid synthase. [PDF]
PLoS ONE, 2012 α-Mangostin, isolated from the hulls of Garcinia mangostana L., was found to have in vitro cytotoxicity against 3T3-L1 cells as well as inhibiting fatty acid synthase (FAS, EC 2.3.1.85). Our studies showed that the cytotoxicity of α-mangostin with IC(50)
Xiaofang Quan +7 more
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Jurnal Penelitian Pendidikan IPA, 2019 Abstract: The purpose of this research is to know the effect of the isolation method of the yield of α-mangostin resulting from mangosteen rind. Mangosteen (Garcinia mangostana L.) is the source of xanthone secondary metabolites. Derivatives xanthone which is the main bioactive compound and becomes a major compound in the mangosteen plant, namely α ...
Idawati, Sri +2 more
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Nanoformulations of α-Mangostin for Cancer Drug Delivery System
Pharmaceutics, 2021 Natural compounds are emerging as effective agents for the treatment of malignant diseases. The active constituent of α-mangostin from the pericarp of Garcinia mangostana L.
Lisna Meylina +4 more
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Journal of Advanced Pharmaceutical Technology & Research, 2021 α-mangostin, γ-mangostin, and xanthone are some of the marker compounds found in mangosteen (Garcinia mangostana Linn.) whose activity on several treatment targets including toward the peroxisome proliferator-activated receptor gamma (PPAR-γ) receptors ...
Rifa'atul Mahmudah +2 more
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Chinese Medicine, 2022 Background Excessive osteoclast activation is an important cause of imbalanced bone remodeling that leads to pathological bone destruction. This is a clear feature of many osteolytic diseases such as rheumatoid arthritis, osteoporosis, and osteolysis ...
Wenkan Zhang +6 more
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Honokiol and Alpha-Mangostin Inhibit Mayaro Virus Replication through Different Mechanisms
Molecules, 2022 Mayaro virus (MAYV) is an emerging arbovirus with an increasing circulation across the Americas. In the present study, we evaluated the potential antiviral activity of the following natural compounds against MAYV and other arboviruses: Sanguinarine, (R ...
Patricia Valdés-Torres +5 more
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