Results 1 to 10 of about 993,255 (173)

Inhibition of Cell Proliferation in an NRAS Mutant Melanoma Cell Line by Combining Sorafenib and α-Mangostin. [PDF]

open access: yesPLoS ONE, 2016
α-Mangostin is a natural product commonly used in Asia for cosmetic and medicinal applications including topical treatment of acne and skin cancer. Towards finding new pharmacological strategies that overcome NRAS mutant melanoma, we performed a cell ...
Yun Xia   +6 more
doaj   +2 more sources

Propolis-Based Nanostructured Lipid Carriers for α-Mangostin Delivery: Formulation, Characterization, and In Vitro Antioxidant Activity Evaluation [PDF]

open access: yesMolecules, 2023
α-Mangostin (a xanthone derivative found in the pericarp of Garcinia mangostana L.) and propolis extract (which is rich in flavonoids and phenols) are known for their antioxidant properties, making them potential supplements for the treatment of ...
Cecep Suhandi   +6 more
doaj   +2 more sources

α-Mangostin Induces Apoptosis and Inhibits Metastasis of Breast Cancer Cells via Regulating RXRα-AKT Signaling Pathway

open access: yesFrontiers in Pharmacology, 2021
Mangostin, which has the function of anti-inflammatory, antioxidant, and anticancer, etc, is one of the main active ingredients of the hull of the mangosteen.
Zhidong Yuan   +2 more
exaly   +3 more sources

Bioactivities of β-Mangostin and Its New Glycoside Derivatives Synthesized by Enzymatic Reactions

open access: yesRoyal Society Open Science, 2023
Beta-mangostin is a xanthone commonly found in the genus Garcinia. Unlike α-mangostin, to date, there have only been a few studies on the biological activity and derivatization of β-mangostin.
Van Thuy Thi Pham   +2 more
exaly   +3 more sources

Water-dispersible unadulterated α-mangostin particles for biomedical applications [PDF]

open access: yesRoyal Society Open Science, 2020
α-Mangostin, the extract from pericarp of Garcinia mangostana L. or mangosteen fruit, has been applied in various biomedical products because of its minimal skin irritation, and prominent anti-inflammatory, antimicrobial and immune-modulating activities.
Jutamad Bumrung   +4 more
doaj   +1 more source

Computational Chemical Study of Pigment of Mangosteen (Garcinia mangostana) Rind Extract as Dye Compound in Dye-Sensitized Solar Cell (DSSC)

open access: yesBiology, Medicine & Natural Product Chemistry, 2021
The electronic transition processes of α-mangostin and β-mangostin as dye compounds in DSSC and their ability to transfer electrons to semiconductors have been studied in theory.
Didik Krisdiyanto   +2 more
doaj   +1 more source

α-Mangostin suppressed melanogenesis in B16F10 murine melanoma cells through GSK3β and ERK signaling pathway

open access: yesBiochemistry and Biophysics Reports, 2021
Mangosteen (Garcinia mangostana L) fruit contains many xanthones in its pericarp, such as α-mangostin. Here, we aimed to elucidate the physiological effect of α-mangostin and the mechanism on melanogenesis in mouse B16F10 cells. The melanin production in
Siqi Zhou   +3 more
doaj   +1 more source

Isolation and Biological Evaluation of Alfa-Mangostin as Potential Therapeutic Agents against Liver Fibrosis

open access: yesBioengineering, 2023
The increased proliferation and activation of hepatic stellate cells (HSCs) are associated with liver fibrosis development. To date, there are no FDA-approved drugs for the treatment of liver cirrhosis.
Yi-Jen Liao   +12 more
doaj   +1 more source

α-Mangostin Extraction from the Native Mangosteen (Garcinia mangostana L.) and the Binding Mechanisms of α-Mangostin to HSA or TRF. [PDF]

open access: yesPLoS ONE, 2016
In order to obtain the biological active compound, α-mangostin, from the traditional native mangosteen (Garcinia mangostana L.), an extraction method for industrial application was explored.
Ming Guo   +4 more
doaj   +1 more source

Molecular dynamics simulation of Fe-NO2 At-alpha mangostin as radiopharmaceutical model for detection of fatty acid synthase in cancer

open access: yesJournal of Advanced Pharmaceutical Technology & Research, 2021
α-mangostin is a xanthone compound isolated from mangosteen pericarp. It is known as an anticancer through induction of apoptotic process by inhibiting fatty acid synthase (FAS) receptor. α-mangostin is a potentially useful ligand for diagnostic purposes
N Elly Rosilawati   +4 more
doaj   +1 more source

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