Results 11 to 20 of about 1,910 (128)
Unraveling the influence of α-mangostin on MDA-MB-231 cell line via WNT/β-catenin signaling pathway: in silico and in vitro approaches [PDF]
Frontiers in PharmacologyThe Wnt/β-catenin signaling pathway is critically involved in breast cancer progression, particularly in the triple-negative subtype (TNBC). Aberrant activation of this pathway promotes tumor proliferation, with β-catenin functioning as a central ...
Riezki Amalia +9 more
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α-Mangostin suppresses ethanol-induced gastric ulceration by regulating the Nrf2/HO-1 and NF-κB/NLRP3/caspase-1 signaling pathways and gut microbiota [PDF]
Heliyonα-Mangostin is a natural xanthone derivative isolated from Camellia atrophy (CA), commonly known as Lichuan black tea (LBT). The present study investigated the ameliorating effect and mechanism of α-mangostin on alcoholic gastric ulcers (GU) in rats.
Suqin Yang +5 more
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Water-dispersible unadulterated α-mangostin particles for biomedical applications [PDF]
Royal Society Open Science, 2020 α-Mangostin, the extract from pericarp of Garcinia mangostana L. or mangosteen fruit, has been applied in various biomedical products because of its minimal skin irritation, and prominent anti-inflammatory, antimicrobial and immune-modulating activities.
Jutamad Bumrung +4 more
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Biology, Medicine & Natural Product Chemistry, 2021 The electronic transition processes of α-mangostin and β-mangostin as dye compounds in DSSC and their ability to transfer electrons to semiconductors have been studied in theory.
Didik Krisdiyanto +2 more
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Biochemistry and Biophysics Reports, 2021 Mangosteen (Garcinia mangostana L) fruit contains many xanthones in its pericarp, such as α-mangostin. Here, we aimed to elucidate the physiological effect of α-mangostin and the mechanism on melanogenesis in mouse B16F10 cells. The melanin production in
Siqi Zhou +3 more
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The Effect of α-Mangostin on the Pharmacokinetic Profile of Tofacitinib in Rats Both In Vitro and In Vivo. [PDF]
Biopharm Drug Disposα‐mangostin (α‐MG) significantly affected tofacitinib metabolism by competing for the same site in CYP3A4. Co‐administration of these two medicines poses a potential herb–drug interaction. ABSTRACT This study investigated the effects of α‐mangostin (α‐MG) on the pharmacokinetics of tofacitinib in vitro and in vivo, aiming to recommend its appropriate ...
Yao J +6 more
europepmc +2 more sources
Inhibition of Cell Proliferation in an NRAS Mutant Melanoma Cell Line by Combining Sorafenib and α-Mangostin. [PDF]
PLoS ONE, 2016 α-Mangostin is a natural product commonly used in Asia for cosmetic and medicinal applications including topical treatment of acne and skin cancer. Towards finding new pharmacological strategies that overcome NRAS mutant melanoma, we performed a cell ...
Yun Xia +6 more
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Cell Transplantation, 2021 α-mangostin has been confirmed to promote the apoptosis of MG-63 cells, but its specific pro-apoptosis mechanism in osteosarcoma (OS) remains further investigation.
Shengsen Yang +3 more
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Bioengineering, 2023 The increased proliferation and activation of hepatic stellate cells (HSCs) are associated with liver fibrosis development. To date, there are no FDA-approved drugs for the treatment of liver cirrhosis.
Yi-Jen Liao +12 more
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Alpha-mangostin inhibits the migration and invasion of A549 lung cancer cells [PDF]
PeerJ, 2018 Several studies have indicated that α-mangostin exerts anti-metastasis and anti-subsistence effects on several types of cancer cells. Especially, the anti-metastatic effect of α-mangostin on cancer cells is a prospective function in cancer treatment ...
Thi Kieu Trang Phan +3 more
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