Results 11 to 20 of about 3,668 (172)
Water-dispersible unadulterated α-mangostin particles for biomedical applications [PDF]
Royal Society Open Science, 2020 α-Mangostin, the extract from pericarp of Garcinia mangostana L. or mangosteen fruit, has been applied in various biomedical products because of its minimal skin irritation, and prominent anti-inflammatory, antimicrobial and immune-modulating activities.
Jutamad Bumrung +4 more
doaj +1 more source
The Effect of α-Mangostin on the Pharmacokinetic Profile of Tofacitinib in Rats Both In Vitro and In Vivo. [PDF]
Biopharm Drug Disposα‐mangostin (α‐MG) significantly affected tofacitinib metabolism by competing for the same site in CYP3A4. Co‐administration of these two medicines poses a potential herb–drug interaction. ABSTRACT This study investigated the effects of α‐mangostin (α‐MG) on the pharmacokinetics of tofacitinib in vitro and in vivo, aiming to recommend its appropriate ...
Yao J +6 more
europepmc +2 more sources
Biology, Medicine & Natural Product Chemistry, 2021 The electronic transition processes of α-mangostin and β-mangostin as dye compounds in DSSC and their ability to transfer electrons to semiconductors have been studied in theory.
Didik Krisdiyanto +2 more
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Biochemistry and Biophysics Reports, 2021 Mangosteen (Garcinia mangostana L) fruit contains many xanthones in its pericarp, such as α-mangostin. Here, we aimed to elucidate the physiological effect of α-mangostin and the mechanism on melanogenesis in mouse B16F10 cells. The melanin production in
Siqi Zhou +3 more
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Inhibition of Cell Proliferation in an NRAS Mutant Melanoma Cell Line by Combining Sorafenib and α-Mangostin. [PDF]
PLoS ONE, 2016 α-Mangostin is a natural product commonly used in Asia for cosmetic and medicinal applications including topical treatment of acne and skin cancer. Towards finding new pharmacological strategies that overcome NRAS mutant melanoma, we performed a cell ...
Yun Xia +6 more
doaj +1 more source
Bioengineering, 2023 The increased proliferation and activation of hepatic stellate cells (HSCs) are associated with liver fibrosis development. To date, there are no FDA-approved drugs for the treatment of liver cirrhosis.
Yi-Jen Liao +12 more
doaj +1 more source
Cell Transplantation, 2021 α-mangostin has been confirmed to promote the apoptosis of MG-63 cells, but its specific pro-apoptosis mechanism in osteosarcoma (OS) remains further investigation.
Shengsen Yang +3 more
doaj +1 more source
Alpha-mangostin inhibits the migration and invasion of A549 lung cancer cells [PDF]
PeerJ, 2018 Several studies have indicated that α-mangostin exerts anti-metastasis and anti-subsistence effects on several types of cancer cells. Especially, the anti-metastatic effect of α-mangostin on cancer cells is a prospective function in cancer treatment ...
Thi Kieu Trang Phan +3 more
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Journal of Advanced Pharmaceutical Technology & Research, 2021 α-mangostin is a xanthone compound isolated from mangosteen pericarp. It is known as an anticancer through induction of apoptotic process by inhibiting fatty acid synthase (FAS) receptor. α-mangostin is a potentially useful ligand for diagnostic purposes
N Elly Rosilawati +4 more
doaj +1 more source
Inhibitory effects of α-Mangostin on T cell cytokine secretion via ORAI1 calcium channel and K+ channels inhibition [PDF]
PeerJ, 2021 Background As one of the main components of mangosteen (Garcinia mangostana), a tropical fruit, α-mangostin has been reported to have numerous pharmacological benefits such as anti-cancer, anti-inflammatory, and anti-allergic effects through various ...
Hyun Jong Kim +7 more
doaj +2 more sources