Results 81 to 90 of about 3,668 (172)

Anti-Acanthamoeba synergistic effect of chlorhexidine and Garcinia mangostana extract or α-mangostin against Acanthamoeba triangularis trophozoite and cyst forms

Scientific Reports, 2021
Acanthamoeba spp. can cause amoebic keratitis (AK). Chlorhexidine is effective for AK treatment as monotherapy, but with a relative failure on drug bioavailability in the deep corneal stroma.
Suthinee Sangkanu, Watcharapong Mitsuwan, Wilawan Mahabusarakam, Tajudeen O. Jimoh, Polrat Wilairatana, Ana Paula Girol, Ajoy K. Verma, Maria de Lourdes Pereira, Mohammed Rahmatullah, Christophe Wiart, Abolghasem Siyadatpanah, Roghayeh Norouzi, Polydor Ngoy Mutombo, Veeranoot Nissapatorn   +13 more
doaj   +1 more source

Standarisasi Mutu Simplisia Kulit Buah Manggis (Garcinia Mangostana L.) [PDF]

, 2014
Kulit buah manggis (Garcinia mangostana L.) diketahui memiliki banyak aktivitas farmakologi sehingga seringdiformulasi dalam suatu sediaan farmasi yang digunakan untuk pengobatan.
A, D. I. (Dewantara), A, I. A. (Indrasuari), D, W. N. (Wijayanti)   +2 more
core  

Emerging cGAS‐STING Agonist‐Based Nanotherapeutics: Mechanistic Insights and Applications in Cancer Combination Therapy

Advanced Science, Volume 12, Issue 36, September 25, 2025.
This review summarizes recent advances in cGAS‐STING agonist‐based nanotherapeutics for cancer combination therapy. It explores nanoparticle‐mediated delivery strategies, underlying molecular mechanisms, and combinatorial applications with chemotherapy, radiotherapy, targeted therapy, phototherapy, sonodynamic therapy, and immunotherapy.
Zhaomeng Wang, Yongjun Wang, Zhonggui He, Caigang Liu   +3 more
wiley   +1 more source

Harnessing the Biological Responses Induced by Nanomaterials for Enhanced Cancer Therapy

Aggregate, Volume 6, Issue 9, September 2025.
Nanomaterial (NM)‐induced toxicity can be strategically repurposed for cancer therapy. This review summarizes the mechanism by which NMs selectively activate specific cellular processes to regulate cell fate independently. We also discussed how NMs‐induced biological responses can be leveraged as therapeutic strategies for cancer treatment.
Liting Wang, Hao Fu, Jiangtao Lin, Meng Zhao, Chuanrong Chen, Hongze Liao, Yourong Duan   +6 more
wiley   +1 more source

Advanced Pharmaceutical Nanotechnologies Applied for Chinese Herbal Medicines

Advanced Science, Volume 12, Issue 31, August 21, 2025.
This review offers a comprehensive overview of pharmaceutical nanotechnology strategies to address limitations associated with the complex material basis and relative mild therapeutic efficacy of Chinese herbal medicines, and summarizes the advantages of these strategies.
Jiameng Li, Ya‐Li Zhang, Tong Jin, Zhaokui Jin, Mengliang Zhu, Guangchao Qing, Jinchao Zhang, Zhisen Wang, Yan Mu, Jin Li, Qian Hua, Xing‐Jie Liang   +11 more
wiley   +1 more source

Depositing α-mangostin nanoparticles to sebaceous gland area for acne treatment

Journal of Pharmacological Sciences, 2015
Although entrapment of nanoparticles of appropriate sizes at hair follicles has been clarified, there is no report on specific clinical application of this finding.
Porntip Pan-In, Atthakorn Wongsomboon, Chayada Kokpol, Nuntaree Chaichanawongsaroj, Supason Wanichwecharungruang   +4 more
doaj   +1 more source

Hair growth and hair tanning activities of mangosteen pericarp water extract on hair dermal papilla cells [PDF]

, 2016
Hair graying represents the most common phenomena of human, and the number of men and women who suffer hair loss is increasing in accordance with changes in lifestyle and nutritional balance. Thus, it is important to develop new therapies to enhance hair
Tan, Ying Fang
core  

β‐Mangostin Attenuates TET2‐Mediated DNA Demethylation of Prkcg in the Prevention of Intervertebral Disc Degeneration

Advanced Science, Volume 12, Issue 32, August 28, 2025.
β‐Mangostin alleviates intervertebral disc degeneration through dual modulation of macrophage polarization and the TET2‐Prkcg axis in nucleus pulposus cells. Abstract Intervertebral disc degeneration (IDD) induced lower back pain is a main cause of disability, resulting in a substantial workforce loss worldwide and placing a substantial burden on the ...
Xiangzhen Kong, Hanwen Gu, Yuanqiang Zhang, Qunbo Meng, Qi Li, Kangle Song, Yanlin Li, Kaiwen Liu, Zhenchuan Liu, Rui Hu, Haoxi Zhai, Tian Li, Zemin Ling, Zhijian Wei, Fuxin Wei, Lei Cheng   +15 more
wiley   +1 more source

Uji Sifat Fisik Cold Cream Kombinasi Ekstrak Kulit Buah Manggis (Garcinia Mangostana L.), Daun Binahong (Anredera Cordifolia), Herba Pegagan (Centella Asiatica) Sebagai Antiluka Bakar [PDF]

, 2015
Pengobatatan luka bakar menggunakan tanaman herbal telah banyak dikembangkan, seperti menggunakan tanaman kulit buah manggis, binahong dan pegagan.Kulit buah manggis memiliki derivat xanton yaitu ?-mangostin yang terkandung daam kulit buah manggis ...
A, S. D. (Swastini), C, D. I. (Desta), G, W. I. (Wirasuta), K, U. N. (Udayana), S, A. C. (Arisanti), T, Y. N. (Yanti)   +5 more
core  

α-Mangostin extracted from the pericarp of the mangosteen (Garcinia mangostana Linn) reduces tumor growth and lymph node metastasis in an immunocompetent xenograft model of metastatic mammary cancer carrying a p53 mutation

BMC Medicine, 2011
Background The mangosteen fruit has a long history of medicinal use in Chinese and Ayurvedic medicine. Recently, the compound α-mangostin, which is isolated from the pericarp of the fruit, was shown to induce cell death in various types of cancer cells ...
Okuno Yasushi, Akamatsu Kanako, Kurose Hitomi, Morimoto Junji, Iinuma Munekazu, Shibata Masa-Aki, Akao Yukihiro, Otsuki Yoshinori   +7 more
doaj   +1 more source