Results 301 to 310 of about 91,213 (314)

When Proteins Go MAD-Misfolded, Amplified, Detected: Advances in α-Synuclein Pathophysiology and RT-QuIC Detection. [PDF]

Mol Neurobiol
Labajová N, Polák A, Cehlár O, Križan P, Hritz J, Kolisek M, Škorvánek M, Škrabana R, Kovačech B, Žilka N.   +9 more
europepmc   +1 more source

Immune involvement in neuropsychiatric disorders: Insights from single‐cell transcriptomic studies

Psychiatry and Clinical Neurosciences, EarlyView.
Neuropsychiatric disorders pose profound challenges to both research and treatment, largely due to their clinical heterogeneity and the limited understanding of their underlying biological mechanisms. While bulk RNA sequencing (bulk RNA‐seq) has been widely used to study gene expression, it cannot resolve cell‐type‐specific signals or detect rare ...
Tsutomu Takeda, Michihiro Toritsuka, Hiroto Tamakoshi, Nakao Iwata, Manabu Makinodan   +4 more
wiley   +1 more source

RETRACTION: α-Synuclein Conformational Antibodies Fused to Penetratin are Effective in Models of Lewy Body Disease. [PDF]

Ann Clin Transl Neurol
europepmc   +1 more source

α-Synuclein Real-Time Quaking-Induced Conversion Assay as a Biomarker for Parkinson's Disease: Clinical Implications and Perspectives. [PDF]

J Clin Neurol
Yu JK, Lee YK, Yea DA, Kim YE.
europepmc   +1 more source

Enhanced Bioavailability of a Thionated IMiD Derivative Nanosuspension for Parkinson's Disease Targeting α-Synuclein. [PDF]

Int J Nanomedicine
Casula L, Palmas MF, Cardia MC, Valenti D, Pini E, Etzi M, Marceddu S, Sinico C, Tweedie D, Greig NH, Kim DS, Carta AR, Lai F.   +12 more
europepmc   +1 more source

A Novel α-Synuclein K58N Missense Variant in a Patient with Parkinson's Disease. [PDF]

Mov Disord
Al-Azzani M, Weber S, Ramalingam N, Ramón M, Shvachiy L, Mestre G, Zech M, Sicking K, de Opakua AI, Jayanthi V, Amaral L, Agarwal A, Chandran A, Chaves SR, Winkelmann J, Trenkwalder C, Schwager M, Pauli S, Dettmer U, Fernández CO, Lautenschläger J, Zweckstetter M, Fernandez-Busnadiego R, Mollenhauer B, Outeiro TF.   +24 more
europepmc   +1 more source

Spermine modulation of Alzheimer's Tau and Parkinson's α-synuclein: implications for biomolecular condensation and neurodegeneration. [PDF]

Nat Commun
Sun X, Saha D, Wang X, Mörman C, Sternke-Hoffmann R, Gerez JA, Herranz-Trillo F, Riek R, Zheng W, Luo J.   +9 more
europepmc   +1 more source

Amyloid formation of alternatively spliced variants of α-synuclein. [PDF]

Protein Sci
SanGiovanni DQ, McGlinchey RP, Lee JC.
europepmc   +1 more source

Live cell imaging of exogenous α-synuclein fibrils in primary microglia and neuron co-cultures. [PDF]

Biochem Biophys Rep
Paquette C, Charlton T, Prowse N, Fortin T, Sun H, Hayley S.   +5 more
europepmc   +1 more source

N-acetylation of α-synuclein enhances synaptic vesicle clustering mediated by α-synuclein and lysophosphatidylcholine

Chuchu Wang, Chunyu Zhao, Xiao Hu, Jiali Qiang, Zhenying Liu, Jinge Gu, Shengnan Zhang, Dan Li, Yaoyang Zhang, Jacqueline Burré, Jiajie Diao, Cong Liu   +11 more
openalex   +1 more source