Results 221 to 230 of about 7,298,112 (344)

SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1

FEBS Open Bio, EarlyView.
Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl, Khawar Amin, Lydia Gabriel, Nils Hampel, Afshin Iram, Julia Hesse, Constanze Wiek, Jasmin Thuy Vy Nguyen, Helmut Hanenberg, Jürgen Scheller, M. Reza Ahmadian, Björn Stork, Doreen M. Floss, Roland P. Piekorz   +13 more
wiley   +1 more source

Water Accelerates in the Hydration Shell of the N- and C-Terminal Domains of α-Synuclein in the Presence of NaCl. [PDF]

J Phys Chem B
Koehler SJ, Vaissier Welborn V.
europepmc   +1 more source

On defining the generalized functions δ^α(z) and δⁿ(x) [PDF]

, 1992
E. K. Koh, ChenQi Li
openalex   +1 more source

Η δυναμική της προσφοράς των ελληνικών σαλιγκαριών στην αγορά της Ε.Ε. [PDF]

, 2008
Μάνδαλος, Ηλίας Α.
core  

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

Εκ του αρχαιοτέρου ναού της Φιγαλείας [PDF]

, 1935
Ρωμαίος, Κωνσταντίνος Α.
core  

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

Traditional Medicinal Plant Dahlia pinnata Selectively Suppresses TNF-α Expression Through Modulation of NF-κB and p38 Signaling. [PDF]

Int J Mol Sci
Woo H, Lee Y, Ahn J, Jin Y, Wu W, Ha UH.
europepmc   +1 more source

Multifunctional Biomass-Based Ionic Liquids/CuCl-Catalyzed CO2-Promoted Hydration of Propargylic Alcohols: A Green Synthesis of α-Hydroxy Ketones [PDF]

Ye Yuan, Siqi Zhang, Kang Duan, Yong Xu, Kaixuan Guo, Cheng Chen, Somboon Chaemchuen, Dongfeng Cao, Francis Verpoort   +8 more
openalex   +1 more source

V2V communications for vehicle safety applications in blind road spots: the highway and urban scenario [PDF]

, 2016
Σπυρόπουλος, Χρήστος Α.
core