Results 141 to 150 of about 624,184 (210)

α7β2 Nicotinic Acetylcholine Receptors Assemble, Function, and Are Activated Primarily via Their α7-α7 Interfaces [PDF]

, 2012
We investigated assembly and function of nicotinic acetylcholine receptors (nAChRs) composed of α7 and β2 subunits. We measured optical and electrophysiological properties of wild-type and mutant subunits expressed in cell lines and Xenopus laevis ...
Pantoja, Rigo, George, Andrew A., Wu, Jie, Bertrand, Daniel, Murray, Teresa A., Whiteaker, Paul, Lester, Henry A., Papke, Roger L., Srinivasan, Rahul, Liu, Qiang, Lukas, Ronald J.   +10 more
core  

Pharmacophore Mapping Combined with dbCICA Reveal New Structural Features for the Development of Novel Ligands Targeting α4β2 and α7 Nicotinic Acetylcholine Receptors. [PDF]

Molecules, 2022
Batista VS, Gonçalves AM, Nascimento-Júnior NM.   +2 more
europepmc   +1 more source

A novel anxiety-associated SNP identified in LYNX2 (LYPD1) is associated with decreased protein binding to nicotinic acetylcholine receptors

Frontiers in Behavioral Neuroscience
IntroductionAnxiety disorders are among the most common mental illnesses in the US. An estimated 31.1% of U.S. adults experience any anxiety disorder at some time in their lives.
Kristin R. Anderson, Wenpeng Cao, Hui Sun Lee, Mark A. Crenshaw, Talulla B. Palumbo, Ethan Fisher-Perez, Amanda DeGraaf, Peter Rogu, Maria A. Beatty, Gabrielle M. Gracias, Gabrielle M. Gracias, Avani V. Pisapati, Katie Hoffman, Krystle J. McLaughlin, Almut Hupbach, Wonpil Im, Wonpil Im, X. Frank Zhang, Julie M. Miwa   +18 more
doaj   +1 more source

Synthesis of full-length homodimer αD-VxXXB that targets human α7 nicotinic acetylcholine receptors. [PDF]

RSC Med Chem, 2022
Ho TNT, Abraham N, Lewis RJ.
europepmc   +1 more source

Sex difference in counts of α4 and α7 nicotinic acetylcholine receptors in the nasal polyps of adults with or without exposure to tobacco smoke

, 2018
ObjectiveTo assess counts of α4 and α7 nicotinic acetylcholine receptors in nasal polyps of adults with or without long-term exposure to cigarette tobacco smoke.MethodsTwenty-two patients with and 22 patients without exposure to cigarette tobacco smoke ...
D A Lara-Sánchez, B B Montaño-Velázquez, A Orozco-Sánchez, F J García-Vázquez, M R Mora-Campos, K Jáuregui-Renaud   +5 more
core   +1 more source

Formulated Curcumin Prevents Paclitaxel-Induced Peripheral Neuropathy through Reduction in Neuroinflammation by Modulation of α7 Nicotinic Acetylcholine Receptors. [PDF]

Pharmaceutics, 2022
Caillaud M, Thompson D, Toma W, White A, Mann J, Roberts JL, Bigbee JW, Gewirtz DA, Damaj MI.   +8 more
europepmc   +1 more source

Effects of apigenin on the function of human α7-nicotinic acetylcholine receptors expressed in Xenopus oocytes

The effects of apigenin, a plant flavonoid, were investigated using the two-electrode voltage-clamp technique on the function of the cloned α7 subunit of the human nicotinic acetylcholine (α7-nACh) receptor expressed in Xenopus oocytes.
Yang, Keun Hang Susan, Oz, Murat, Hasan, Sonia, Nurulain, Syed, Prytkova, Tatiana, Isaev, Dmytro, Sadek, Bassem, Al Kury, Lina T.   +7 more
core   +1 more source

Astrocytic α7-nicotinic acetylcholine receptors mediate pain information processing and perception

Neurobiology of Disease
The astrocyte–neuron network in the primary somatosensory cortex (S1) responds dynamically to pain stimuli and plays a pivotal role in pain processing.
Teng Teng, Shaofan Yang, Jin Li, Haoyu Wang, Fengjuan Wu, Yong He, Jihua Fan, Hongwei Shi, Mingzhu Huang, Xiang Zhou, Ying Liu, Mingyue Gong, Chuanyan Yang, Huiquan Wang, Zhenlu Cai, Hongli Li, Kuan Zhang   +16 more
doaj   +1 more source

Is SARS-CoV-2 Spike glycoprotein impairing macrophage function via α7-nicotinic acetylcholine receptors? [PDF]

Food Chem Toxicol, 2021
Tanmay S, Labrou D, Farsalinos K, Poulas K.   +3 more
europepmc   +1 more source

Curcumin Potentiates α7 Nicotinic Acetylcholine Receptors and Alleviates Autistic-Like Social Deficits and Brain Oxidative Stress Status in Mice. [PDF]

Int J Mol Sci, 2021
Jayaprakash P, Isaev D, Shabbir W, Lorke DE, Sadek B, Oz M.   +5 more
europepmc   +1 more source