Results 211 to 220 of about 2,121,152 (251)

Impaired Windkessel function and proximal aortic stiffness: Linking vascular ageing to cognitive decline

Experimental Physiology, EarlyView.
Abstract Central arterial stiffening, particularly of the proximal aorta, is increasingly recognised as a pivotal contributor to cardiovascular disease, dementia, and mild cognitive impairment. Loss of Windkessel function amplifies pulsatile pressure, reduces diastolic perfusion and accelerates microvascular damage in the brain.
Jun Sugawara, Hirofumi Tanaka
wiley   +1 more source

Cerebral haemodynamic responses to inspiratory muscle work

Experimental Physiology, EarlyView.
Abstract Fatiguing inspiratory work has been shown to evoke a sympathetically mediated reflex that has systemic cardiovascular consequences, including increases in heart rate and blood pressure and a decrease in resting limb vascular conductance. Moreover, the response to this reflex appears to be attenuated in females compared with males.
Andrew H. Ramsook, Morgan A. Hughes, Wyatt W. Pruter, Kevin L. Webb, Ali Ataie, Chad C. Wiggins, Gabrielle A. Dillon, Sarah E. Baker, Michael J. Joyner   +8 more
wiley   +1 more source

Sex‐related differences in the peripheral vascular response to hypoxia: Implications in health and relevance for obstructive sleep apnoea

Experimental Physiology, EarlyView.
Abstract The incidence and presentation of obstructive sleep apnoea, as well as hypertension and cardiovascular disease, have been reported to differ by sex. It is thus reasonable to propose mechanisms contributing to subsequent pathology differ by sex. This concept is supported from a pre‐pathological perspective, as sex differences have been observed
Dain W. Jacob, Sara E. Mascone, Natasha G. Boyes, Anna M. Gonsalves, Jacqueline K. Limberg   +4 more
wiley   +1 more source

Feasibility Study of Single-Photon Emission Computed Tomography with Iodine-123 Labeled Metaiodobenzylguanidine for Preclinical Evaluation of Labetalol as a β-Adrenergic Receptor Blocker. [PDF]

Mol Pharm
Choi Y, Lee ES, Woo SK, Lee KC, Chung HK, Kang JH.   +5 more
europepmc   +1 more source

Lower limb blood flow responses during higher‐ and lower‐load bilateral leg press exercise

Experimental Physiology, EarlyView.
Abstract The local blood flow response to resistance exercise (RE) is complicated by local muscular contractions and large swings in perfusion pressure. The magnitude of these responses might vary according to exercise intensity, number of sets and number of repetitions, and as a result, the local shear environment during RE remains uncharacterized. We
Eudoxia Zafiris, Jeremy. N. Cohen, Tania J. Pereira, Jason S. Au   +3 more
wiley   +1 more source

Passive hyperthermia increases blood circulation in specific regions, largely independent of conduit artery mechanics and cardiac performance

Experimental Physiology, EarlyView.
Abstract Passive hyperthermia increases net peripheral and systemic blood flow in humans and other animals, yet the underlying haemodynamic forces that selectively accelerate blood movement remain incompletely characterized. Wave intensity analysis offers insight into the respective contributions of the heart and the vascular system to changes in blood
Nuno Koch Esteves, Kazuhito Watanabe, Francesca R. Cavallo, Ashraf W. Khir, José González‐Alonso   +4 more
wiley   +1 more source

Acute exercise‐induced lipolysis and increase in levels of fatty acid esters of hydroxy fatty acids in adipose tissue are impaired in obese and aged mice

Experimental Physiology, EarlyView.
Abstract Improving adipose tissue (AT) metabolism through exercise might increase production of lipokines from the fatty acid esters of hydroxy fatty acids (FAHFA) family. Although exercise training can increase insulin sensitivity and levels of specific FAHFA in AT and the circulation in humans, the effects of acute exercise on FAHFA levels remain ...
Marko Mitrovic, Olga Horakova, Martin Riecan, Veronika Kleinova, Tomas Cajka, Lenka Rossmeislova, Ondrej Kuda, Martin Rossmeisl   +7 more
wiley   +1 more source

Thermophysiological and perceptual responses to exercise heat stress in people with cystic fibrosis on Elexacaftor/Tezacaftor/Ivacaftor

Experimental Physiology, EarlyView.
Abstract The objective of this study was to investigate thermophysiological and perceptual responses to exercise heat stress in people with cystic fibrosis (pwCF) on Elexacaftor/Tezacaftor/Ivacaftor (ETI) versus healthy controls, and to explore their lived experiences of heat stress.
Lauren J. Clayton, Jo Corbett, Anthony I. Shepherd, Heather Massey, Don S. Urquhart, Neil Maxwell, Gary Connett, Mark Allenby, Julian Legg, Thomas Daniels, Zoe L. Saynor   +10 more
wiley   +1 more source

Acute lower leg transcutaneous electrical nerve stimulation increases leg blood flow and exercise capacity in patients with peripheral arterial disease

Experimental Physiology, EarlyView.
Abstract We tested the hypothesis that two different durations of lower leg transcutaneous electrical nerve stimulation (TENS) increase post‐TENS popliteal artery blood flow (PABF), popliteal vascular conductance (PVC), and 6‐min walk distance (6MWD) in patients with peripheral artery disease (PAD).
Thomas K. Pellinger, Catherine B. Neighbors, Joshua C. Hefta, Patrick H. Luo, Carl B. Suarez, Erotokritos T. Varlas, Grant H. Simmons, Brett J. Wong   +7 more
wiley   +1 more source

The cold‐water immersion recovery–adaptation paradox: Reconciling acute parasympathetic and analgesic benefits with chronic hypertrophy attenuation

Experimental Physiology, EarlyView.
Abstract Cold‐water immersion (CWI) is among the most widely used post‐exercise recovery modalities in elite sport and clinical rehabilitation, yet a fundamental paradox now emerges from the evidence: the same protocols that accelerate parasympathetic reactivation and reduce perceived muscle soreness also suppress the molecular and cellular machinery ...
Jose Francisco Tornero‐Aguilera, Jose Lozano‐Meca, Miguel López‐Moreno, Edgar Simón Sancho‐Haro, Mario Muñoz‐López, Eneko Baz‐Valle, José Francisco López‐Gil, Rodrigo Yáñez‐Sepúlveda, Vicente Javier Clemente‐Suárez   +8 more
wiley   +1 more source