Advances in the synthesis of β-alanine [PDF]
Frontiers in Bioengineering and Biotechnology, 2023 β-Alanine is the only naturally occurring β-type amino acid in nature, and it is also one of the very promising three-carbon platform compounds that can be applied in cosmetics and food additives and as a precursor in the chemical, pharmaceutical and ...
Peng Song +5 more
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β-Alanine Is an Unexploited Neurotransmitter in the Pathogenesis and Treatment of Alzheimer’s Disease [PDF]
NeuroSciAlzheimer’s disease (AD) remains an unmet medical challenge, as there are no effective therapies that alter the disease’s progression. While approaches have targeted molecules like acetylcholine (ACh) and glutamate, these strategies have provided only ...
Cindy M. Wozniczka, Donald F. Weaver
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Study on the construction technology of β-alanine synthesizing Escherichia coli based on cellulosome assembly [PDF]
Frontiers in Bioengineering and Biotechnology, 2023 Introduction: β-Alanine is the only β-amino acid in nature; it is widely used in food additives, medicines, health products, and surfactants. To avoid pollution caused by traditional production methods, the synthesis of β-alanine has been gradually ...
Jie Lu +19 more
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Non-proteinogenic β-alanine metabolism in Halomonas sp. MNB13 regulates manganese reduction in deep-sea ferromanganese nodules [PDF]
Applied and Environmental MicrobiologyDeep-sea ferromanganese nodules are valuable materials for investigating microorganism-mediated geochemical cycling of manganese. While many microbial metabolic pathways are closely associated with manganese reduction, few studies have examined the role ...
Shuju Guo +6 more
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Salmonella exploits host- and bacterial-derived β-alanine for replication inside host macrophages [PDF]
eLifeSalmonella is a major foodborne pathogen that can effectively replicate inside host macrophages to establish life-threatening systemic infections. Salmonella must utilize diverse nutrients for growth in nutrient-poor macrophages, but which nutrients are ...
Shuai Ma +9 more
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MpADC, an l-aspartate-α-decarboxylase, from Myzus persicae, that enables production of β-alanine with high yield by whole-cell enzymatic catalysis [PDF]
Biotechnology for Biofuels and Bioproducts, 2023 Background β-Alanine is a precursor of many important pharmaceutical products and food additives, its market demand is continuously increasing nowadays.
Pengfu Liu +7 more
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Effects of β-alanine on intestinal development and immune performance of weaned piglets [PDF]
Animal Nutrition, 2023 Beta-alanine is an important amino acid involved in several metabolic reactions in the body. The study aimed to investigate the effect of β-alanine supplementation on intestinal development and the immune performance of weaned piglets.
Linlin Chen +11 more
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Synthesis of β‐Alanine From Isoleucine and Propionate Catabolism via Aminotransferases [PDF]
Plant DirectIn plants, the nonproteinogenic amino acid β‐alanine plays a role in response to hypoxia, flooding, drought, heat, and heavy metal stress conditions. It is also a key intermediate in the synthesis of essential molecules including vitamin B5 and coenzyme ...
Margo H. Goldfarb +7 more
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Effect of β-Alanine Metabolite on Gut Integrity and Immunity in Commercial Broiler Chickens Infected with Eimeria maxima [PDF]
Animals(1) Background: In a metabolomics analysis conducted to investigate the mechanisms behind the growth-promoting effects of probiotics in broilers, β-alanine was found to be significantly elevated.
Inkyung Park +5 more
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One-Pot Synthesis of β-Alanine from Fumaric Acid via an Efficient Dual-Enzyme Cascade Biotransformation [PDF]
BiomoleculesAs the only naturally occurring β-amino acid, β-alanine has important application prospects in many fields. Driven by the huge demand, biosynthesis is becoming more and more popular as a potential alternative to the chemical synthesis of β-alanine ...
Zifu Ni +4 more
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