Results 41 to 50 of about 1,157,409 (244)
The Arabidopsis thaliana gene annotated by the locus tag At3g08860 encodes alanine aminotransferase
Plant Direct, 2019 The aminotransferase gene family in the model plant Arabidopsis thaliana consists of 44 genes, eight of which are suggested to be alanine aminotransferases.
Anutthaman Parthasarathy +3 more
doaj +1 more source
, 2012 β-Alanine is rapidly developing as one of the most popular sport supplements used by strength/power athletes worldwide. The popularity of β-alanine stems from its unique ability to enhance intramuscular buffering capacity and thereby attenuating fatigue.
Stout, Jeffrey R. +2 more
core +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Exercise and β-alanine supplementation on carnosine-acrolein adduct in skeletal muscle
Redox Biology, 2018 Previous studies have demonstrated that exercise results in reactive aldehyde production and that β-alanine supplementation increases carnosine content in skeletal muscle.
Victor H. Carvalho +7 more
doaj +1 more source
Structural and biochemical analysis of a B12 superbinder
FEBS Letters, EarlyView.BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
Advances in Redox Research, 2022 Type 2 diabetes is a disease characterized by dysregulation of glucose homeostasis, with numerous diabetic complications attributable to the resulting chronic exposure of cells and tissues to elevated concentrations of glucose and fatty acids.
Merell P. Billacura +5 more
doaj +1 more source
, 2014 Screening for cross-reactivity of Alanine and Clozapine (CLZ).
Sheryl Chocron (677029)
core +1 more source
FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
Enzyme-catalyzed amine-functionalization of poly(ethylene-glycol)
eXPRESS Polymer Letters, 2022 This paper presents a new method for the amine-functionalization of poly(ethylene glycol) (PEG) of Mn =2050 g/mol via Candida antarctica lipase B (CALB)-catalyzed esterification of tert-butyloxycarbonyl (tBOC)-protected β-Alanine and L-Alanine.
Judit Eva Puskas +3 more
doaj +1 more source
Effects of buffering agents on high-intensity exercise performance and capacity [PDF]
, 2012 High-intensity exercise results in hydrogen ion accumulation, which can have a deleterious effect on muscle function, and thus exercise tolerance. Buffering agents are commonly used to enhance exercise performance and capacity. Two such agents, β-alanine
Saunders, B
core