Results 171 to 180 of about 29,210 (204)

Strain Release of 1‐Azabicyclo[1.1.0]butanes as a Gateway to Highly Functionalized Azetidines: New Strategies and Structural Motifs

open access: yesChemistry – A European Journal, EarlyView.
Over the past decade, the interest in azetidines has continuously risen, by virtue of their highly appealing pharmaceutical properties. Monocyclic, spirocyclic, and bridged azetidines can be accessed by leveraging 1‐azabicyclo[1.1.0]butanes as precursors.
Yuri Gelato   +3 more
wiley   +1 more source

Screening of flavor-enhancing yeast and its role in fig fermentation. [PDF]

open access: yesFront Bioeng Biotechnol
Chen Z   +8 more
europepmc   +1 more source

Synthesis and Biological Evaluation of Well‐Defined M6P(n)‐Modified Glycopeptides for Targeted Protein Degradation

open access: yesChemistry – A European Journal, EarlyView.
A synthetic methodology has been developed to prepare multifunctional M6P and M6Pn ligands of different valency. The glycopeptides were conjugated to cetuximab and then examined to mediate cellular uptake of fluorescently labeled EGFRvIII. Only cetuximab modified by glycopeptides having 3 or 6 M6P or M6Pn residues demonstrated greater uptake.
Patrycja Lenartowicz   +6 more
wiley   +1 more source

Bioinspired Glycosylpyridinium Donors for Mild and Stereoselective Glycosylation. [PDF]

open access: yesJACS Au
Tang L   +7 more
europepmc   +1 more source

Flipping the Card With Enantiodivergent Organocatalysis

open access: yesChemistry – A European Journal, EarlyView.
This minireview elaborates on recent organocatalytic strategies for achieving enantiodivergence—the ability to access both product enantiomers using a single chiral catalyst. It highlights how achiral stimuli, such as solvent polarity and chemical additives, along with minimal catalyst modifications, trigger stereochemical inversions in reactions ...
Debora Iapadre   +3 more
wiley   +1 more source

Helical Folding of Abiotic Chiral Poly(phosphodiester)s

open access: yesChemistry – A European Journal, EarlyView.
Design and structural analysis of a new class of phosphodiester foldamers are presented. These oligomers that fold into single helical architecture showed length and temperature stability dependence comparable to DNA duplexes. ABSTRACT Functions of biomolecules are intimately linked to their structures which result from the folding of a linear sequence
Ranajit Barman   +3 more
wiley   +1 more source

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