Results 151 to 160 of about 748,483 (181)
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Journal of Pharmaceutical Sciences & Emerging Drugs, 2016
Characterization of Darunavir: Β-Cyclodextrin complex and Comparison with the Forms of Darunavir Ethanolate and Hydrate Darunavir, a protease inhibitor used in the treatment of HIV infection, presents solubility problems and so it was complexed with β-cyclodextrin. Complexation increased the solubility of the drug in more than 28 times compared to the
Ana Carolina Kogawa +1 more
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Characterization of Darunavir: Β-Cyclodextrin complex and Comparison with the Forms of Darunavir Ethanolate and Hydrate Darunavir, a protease inhibitor used in the treatment of HIV infection, presents solubility problems and so it was complexed with β-cyclodextrin. Complexation increased the solubility of the drug in more than 28 times compared to the
Ana Carolina Kogawa +1 more
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Journal of the Chemical Society, Perkin Transactions 2, 2001
β-Cyclodextrin (β-CDx) derivatives modified with p-xylylenediamine at the 3-position, mono-3-deoxy-3-[4-(aminomethyl)benzylamino]-β-CDx (1; β-CDx-3-p-xylylenediamine) was prepared by the reaction of β-CDx-2,3-manno-epoxide with p-xylylenediamine. The circular dichroism properties of 1 are compared with those of the corresponding β-CDx derivative ...
Kwanghee Koh Park +4 more
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β-Cyclodextrin (β-CDx) derivatives modified with p-xylylenediamine at the 3-position, mono-3-deoxy-3-[4-(aminomethyl)benzylamino]-β-CDx (1; β-CDx-3-p-xylylenediamine) was prepared by the reaction of β-CDx-2,3-manno-epoxide with p-xylylenediamine. The circular dichroism properties of 1 are compared with those of the corresponding β-CDx derivative ...
Kwanghee Koh Park +4 more
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Investigations into the structure and composition of β-cyclodextrin/poly(acrylic acid) microspheres
International Journal of Pharmaceutics, 1999Microspheres composed of the hydrophilic polymer poly(acrylic acid) (PAA), with and without beta-cyclodextrin (beta-CD), were prepared by a water-in-oil (w/o) solvent evaporation technique. Microspheres were characterised for particle size, beta-CD and residual oil content.
D C, Bibby, N M, Davies, I G, Tucker
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International Journal of Pharmaceutics, 1999
The interaction of piroxicam with beta-cyclodextrin (beta-CD), hexadecyltrimethylammonium bromide-based microemulsion (ME), and ME in the presence of beta-CD aimed at the optimization of topical drug delivery was studied. UV-VIS absorption spectra at pH 5.5 were obtained with and without beta-CD and ME.
Dalmora, MEA, Oliveira, Anselmo Gomes de
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The interaction of piroxicam with beta-cyclodextrin (beta-CD), hexadecyltrimethylammonium bromide-based microemulsion (ME), and ME in the presence of beta-CD aimed at the optimization of topical drug delivery was studied. UV-VIS absorption spectra at pH 5.5 were obtained with and without beta-CD and ME.
Dalmora, MEA, Oliveira, Anselmo Gomes de
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European Journal of Pharmaceutics and Biopharmaceutics, 2000
The in vivo ocular bioavailability of hydrocortisone (HC) in the NZW rabbit was determined following topical administration of solutions containing HC (1%) with hydroxypropyl-beta-cyclodextrin (HP-beta-CD) alone, or containing the mucoadhesive, viscosity enhancing polymers sodium hyaluronate (0.2 and 0.5% w/v) or Carbopol 934P (0.1% w/v).
A R, Bary, I G, Tucker, N M, Davies
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The in vivo ocular bioavailability of hydrocortisone (HC) in the NZW rabbit was determined following topical administration of solutions containing HC (1%) with hydroxypropyl-beta-cyclodextrin (HP-beta-CD) alone, or containing the mucoadhesive, viscosity enhancing polymers sodium hyaluronate (0.2 and 0.5% w/v) or Carbopol 934P (0.1% w/v).
A R, Bary, I G, Tucker, N M, Davies
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Journal of the Chemical Society, Dalton Transactions, 2001
A novel β-CD derivative, mono[6-deoxy-6-(2-butenedinitrile-2,3-dimercapto sodium salt)]–β-CD 1, and its inclusion compound 2 with CpMnI(CO)3 have been prepared and characterized by spectroscopic methods. The inclusion complexation significantly stabilized both the host and guest.
Chang-Sheng Lu +5 more
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A novel β-CD derivative, mono[6-deoxy-6-(2-butenedinitrile-2,3-dimercapto sodium salt)]–β-CD 1, and its inclusion compound 2 with CpMnI(CO)3 have been prepared and characterized by spectroscopic methods. The inclusion complexation significantly stabilized both the host and guest.
Chang-Sheng Lu +5 more
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Talanta, 2001
The formation constant for a 1:1 binary complex between 6-bromo-2-naphthol (6B2N) and beta-cyclodextrin (CD) in aqueous solution was determined by both absorptimetric and fluorimetric methods. Room-temperature phosphorescence (RTP) was induced by adding small amounts of different apolar liquids as the third component, with cyclohexane producing the ...
G M, Escandar, M A, Boldrini
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The formation constant for a 1:1 binary complex between 6-bromo-2-naphthol (6B2N) and beta-cyclodextrin (CD) in aqueous solution was determined by both absorptimetric and fluorimetric methods. Room-temperature phosphorescence (RTP) was induced by adding small amounts of different apolar liquids as the third component, with cyclohexane producing the ...
G M, Escandar, M A, Boldrini
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Talanta, 1999
2,6 Didodecyl beta cyclodextrin (2,6ddbetaCD) modified ion-selective electrodes (ISEs) were used in discrete solutions and in a flow injection analysis manifold for monitoring the local anaesthetic lidocaine hydrochloride (lignocaine) in the presence of endogenous cations and proteins.
R, Kataky, K, Toth, S, Palmer, Z, Feher
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2,6 Didodecyl beta cyclodextrin (2,6ddbetaCD) modified ion-selective electrodes (ISEs) were used in discrete solutions and in a flow injection analysis manifold for monitoring the local anaesthetic lidocaine hydrochloride (lignocaine) in the presence of endogenous cations and proteins.
R, Kataky, K, Toth, S, Palmer, Z, Feher
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Templating Odd Numbered Magnetic Rings: Oxovanadium Heptagons Sandwiched by β-Cyclodextrins
Journal of the American Chemical Society, 2009The oxovanadium heptagons sandwiched by beta-cyclodextrins showed stepped magnetization curves, which were characteristic of level crossings of spin sublevels. Doubly degenerate ground Kramers' doublets split into two spin states, and the splitting energy gaps depend upon ring distortions.
Hoshino +5 more
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Talanta, 2000
Abstract The influence of different factors on the room-temperature phosphorescence (RTP) emission from the inclusion complex between α-cyclodextrin (α-CD) and 6-bromo-2-naphthol (BN) was analyzed. Although RTP signals are detected even in aerated solutions, an efficient enhancement of the phosphorescence emission (about 13 times) is obtained when ...
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Abstract The influence of different factors on the room-temperature phosphorescence (RTP) emission from the inclusion complex between α-cyclodextrin (α-CD) and 6-bromo-2-naphthol (BN) was analyzed. Although RTP signals are detected even in aerated solutions, an efficient enhancement of the phosphorescence emission (about 13 times) is obtained when ...
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