Results 1 to 10 of about 1,058,936 (167)

In Situ Targeting RGD-Modified Cyclodextrin Inclusion Complex/Hydrogel Hybrid System for Enhanced Glioblastoma Therapy [PDF]

Pharmaceutics
Background/Objectives: Glioblastoma (GBM) remains the most aggressive primary brain tumor, characterized by high malignancy, recurrence rate, and dismal prognosis, thereby demanding innovative therapeutic strategies.
Xiaofeng Yuan, Zhenhua Wang, Pengcheng Qiu, Zhenhua Tong, Bingwen Wang, Yingjian Sun, Xue Sun, Lu Sui, Haiqiang Jia, Jiajun Wang, Haifeng Tang, Weiliang Ye   +11 more
doaj   +2 more sources

New Antioxidant Triphenol-Derived Hydrazide-Hydrazone Thiazole: Formation and Analysis of Inclusion Complex with β-CD Using Experimental and Computational Approaches [PDF]

Molecules
A new water-soluble not-colored antioxidant (Z)-N′-(4-(3,4-dihydroxyphenyl)-3-ethylthiazol-2(3H)-ylidene)-4-hydroxybenzohydrazide hydrochloride (DHTH) was obtained and characterized.
Adrian Pîrnău, Mihaela Mic, Călin G. Floare, Ovidiu Oniga, Smaranda Dafina Oniga, Ovidiu Crișan, Laurian Vlase, Gabriel Marc   +7 more
doaj   +2 more sources

Crystal structure and supramolecular features of a host–guest inclusion complex based on A1/A2-hetero-difunctionalized pillar[5]arene [PDF]

Acta Crystallographica Section E: Crystallographic Communications
A host–guest supramolecular inclusion complex was obtained from the co-crystallization of A1/A2-bromobutoxy-hydroxy difunctionalized pillar[5]arene (PilButBrOH) with adiponitrile (ADN), C47H53.18Br0.82O10·C6H8N2.
Mickey Vinodh, Talal F. Al-Azemi
doaj   +2 more sources

Nanosponge as a drug delivery system [PDF]

Records of Pharmaceutical & Biomedical Sciences, 2020
Nanosponges are colloidal carriers that potentially improve the aqueous solubility of poorly water-soluble drug, retarding its release, improving bioavailability, enhancing physical and chemical stability and decrease skin irritation as well. In addition,
Norehan Ghourab, ahmed gardouh, Shadeed Gad, Yasser Moustafa   +3 more
doaj   +1 more source

1-[1,4-Bis(but-3-en-1-yloxy)]-2,3,4,5-(1,4-dimethoxy)pillar[5]arene–1,4-dibromobutane 1:1 inclusion complex

IUCrData, 2023
In the title compound, C51H58O10·C4H8Br2, both the host and guest are completed by crystallographic twofold symmetry (one carbon atom of the host lies on the rotation axis).
Mickey Vinodh, Talal F. Al-Azemi
doaj   +1 more source

Complexity Thresholds in Inclusion Logic [PDF]

Information and Computation, 2019
Logics with team semantics provide alternative means for logical characterization of complexity classes. Both dependence and independence logic are known to capture non-deterministic polynomial time, and the frontiers of tractability in these logics are relatively well understood.
Miika Hannula, Lauri Hella
openaire   +7 more sources

Improvement of solubility and pharmacokinetic profile of hepatoprotector icariin through complexation with HP-γ-cyclodextrin

Frontiers in Pharmacology, 2023
Icariin as a hepatoprotector from Herba epimedii can expand the cardiovascular and cerebral blood vessels, promote hematopoietic functions, enhance the immune system and show anti-liver tumor activities.
Yili Ding, Bo Yu, Shuzhen Zhou, Charles Ding, Zhiyuan Zhang, Shufeng Xu, Zhe Xu   +6 more
doaj   +1 more source

Supramolecular Arrangement of Doxycycline with Sulfobutylether-β-Cyclodextrin: Impact on Nanostructuration with Chitosan, Drug Degradation and Antimicrobial Potency

Pharmaceutics, 2023
Doxycycline (DX) is a well-established and broad-spectrum antimicrobial drug. However, DX has drawbacks, such as physicochemical instability in aqueous media and bacterial resistance.
Renata Carvalho Feitosa, Juliana Souza Ribeiro Costa, Marcelo van Vliet Lima, Elina Sawa Akioka Ishikawa, Karina Cogo Müller, Fernando Bonin Okasaki, Edvaldo Sabadini, Claudia Garnero, Marcela Raquel Longhi, Vladimir Lavayen, Arnóbio Antônio da Silva-Júnior, Laura Oliveira-Nascimento   +11 more
doaj   +1 more source

Fabrication of Nanostructured Supramolecules through Helical Inclusion of Amylose toward Hydrophobic Polyester Guests, Biomimetically through Vine-Twining Polymerization Process

Biomimetics, 2023
This review article presents the biomimetic helical inclusion of amylose toward hydrophobic polyesters as guests through a vine-twining polymerization process, which has been performed in the glucan phosphorylase (GP)-catalyzed enzymatic polymerization ...
Jun-ichi Kadokawa
doaj   +1 more source

Melarsoprol–cyclodextrins inclusion complexes [PDF]

International Journal of Pharmaceutics, 2005
Melarsoprol, a water-insoluble drug, is mainly used in the treatment of trypanosomiasis and has demonstrated an in vitro activity on myeloid and lymphoid leukemia derived cell lines. It is marketed as a very poorly tolerated non-aqueous solution (Arsobal).
Stéphane, Gibaud, Siham Ben, Zirar, Pierre, Mutzenhardt, Isabelle, Fries, Alain, Astier   +4 more
openaire   +2 more sources