Results 1 to 10 of about 46,196 (262)

Chitosan-EDTA-cellulose functionalized with β-cyclodextrin as a pH-sensitive bio-based nanocarrier for curcumin drug delivery [PDF]

Scientific Reports
In this work, chitosan/cellulose/β-cyclodextrin nanostructure was synthesized by cross-linking chitosan and cellulose with EDTA followed by bridging with ethylenediamine-β-cyclodextrin.
Negin Rostami, Mohammad G. Dekamin, Mohammad Reza Naimi-Jamal   +2 more
doaj   +2 more sources

Testing the Protective Effects of Sulfobutylether-Βeta-Cyclodextrin (SBECD) and Sugammadex against Chlorpromazine-Induced Acute Toxicity in SH-SY5Y Cell Line and in NMRI Mice

Pharmaceutics, 2022
Chlorpromazine (CPZ) is an antipsychotic drug which can cause several adverse effects and drug poisoning. Recent studies demonstrated that CPZ forms highly stable complexes with certain cyclodextrins (CDs) such as sulfobutylether-β-CD (SBECD) and ...
Eszter Fliszár-Nyúl, Rita Csepregi, Gábor Benkovics, Lajos Szente, Miklós Poór   +4 more
doaj   +1 more source

Streptococcus agalactiae amylomaltase offers insight into the transglycosylation mechanism and the molecular basis of thermostability among amylomaltases

Scientific Reports, 2021
Amylomaltase (AM) catalyzes transglycosylation of starch to form linear or cyclic oligosaccharides with potential applications in biotechnology and industry.
Suthipapun Tumhom, Pitchanan Nimpiboon, Kittikhun Wangkanont, Piamsook Pongsawasdi   +3 more
doaj   +1 more source

Cyclodextrin: A prospective nanocarrier for the delivery of antibacterial agents against bacteria that are resistant to antibiotics

Heliyon, 2023
Supramolecular chemistry introduces us to the macrocyclic host cyclodextrin, which has a hydrophobic cavity. The hydrophobic cavity has a higher affinity for hydrophobic guest molecules and forms host-guest complexation with non-covalent interaction ...
Pranoy Saha, Md Rajdoula Rafe
doaj   +1 more source

The Biological Fate of Pharmaceutical Excipient β-Cyclodextrin: Pharmacokinetics, Tissue Distribution, Excretion, and Metabolism of β-Cyclodextrin in Rats

Molecules, 2022
β-cyclodextrin has a unique annular hollow ultrastructure that allows encapsulation of various poorly water-soluble drugs in the resulting cavity, thereby increasing drug stability.
Kunqian Mu, Kaiwen Jiang, Yue Wang, Zihan Zhao, Song Cang, Kaishun Bi, Qing Li, Ran Liu   +7 more
doaj   +1 more source

Weak complexation of 5-fluorouracil with β-cyclodextrin, carbonate, and dianhydride crosslinked β-cyclodextrin: in vitro and in silico studies

Research in Pharmaceutical Sciences, 2022
Background and purpose: Several pharmaceutical formulations were investigated to improve the solubility of 5-fluorouracil to enhance bioavailability and therapeutic efficacy. This study aimed to examine the potential use of cyclodextrin-based nanosponges
Hadeia Mashaqbeh, Rana Obaidat, Nizar A Al-Shar’i, Tamam El-Elimat, Soraya Alnabulsi   +4 more
doaj   +1 more source

Cyclodextrin-Enabled Polymer Composites for Packaging †

Molecules, 2018
Cyclodextrin complexes of fragrances, antimicrobial agents, dyes, insecticides, UV-filters can be incorporated into polymers (packaging films, trays, containers) either to ensure the slow release or a homogeneous distribution of the complexed substances.
Lajos Szente, Éva Fenyvesi
doaj   +1 more source

Insulin Complexation with Cyclodextrins—A Molecular Modeling Approach

Molecules, 2022
Around 5% of the population of the world is affected with the disease called diabetes mellitus. The main medication of the diabetes is the insulin; the active form is the insulin monomer, which is an instable molecule, because the long storage time, or ...
Pálma Bucur, Ibolya Fülöp, Emese Sipos   +2 more
doaj   +1 more source

Synthetic strategies for the fluorescent labeling of epichlorohydrin-branched cyclodextrin polymers

Beilstein Journal of Organic Chemistry, 2014
The fluorescent tagging of cyclodextrin derivatives enlarges their spectroscopic properties thus generating chemosensors, biological tools for visualization and sophisticated photoresponsive devices.
Milo Malanga, Mihály Bálint, István Puskás, Kata Tuza, Tamás Sohajda, László Jicsinszky, Lajos Szente, Éva Fenyvesi   +7 more
doaj   +1 more source

Synthesis of modified cyclic and acyclic dextrins and comparison of their complexation ability

Beilstein Journal of Organic Chemistry, 2014
We compared the complex forming ability of α-, β- and γ-cyclodextrins (α-CD, β-CD and γ-CD) with their open ring analogs. In addition to the native cyclodextrins also modified cyclodextrins and the corresponding maltooligomers, functionalized with ...
Kata Tuza, László Jicsinszky, Tamás Sohajda, István Puskás, Éva Fenyvesi   +4 more
doaj   +1 more source