Results 21 to 30 of about 84,390 (296)

Homo- and hetero-difunctionalized β-cyclodextrins: Short direct synthesis in gram scale and analysis of regiochemistry

open access: yesBeilstein Journal of Organic Chemistry, 2019
The regioselective difunctionalization of cyclodextrins (CDs) leading to derivatives amenable to further transformations is a daunting task due to challenging purification and unambiguous characterization of the obtained regioisomers with similar ...
Gábor Benkovics   +6 more
doaj   +1 more source

Cyclodextrin nanofibers by electrospinning [PDF]

open access: yesChemical Communications, 2010
We have demonstrated that cyclodextrin (CD) (a non-polymeric system) can be electrospun into nanofibers by itself; methyl-beta-cyclodextrin (MbetaCD) nanofibers were electrospun and it was observed that the success of the electrospinning of the CD nanofibers strongly depends on (i) type of solvent, (ii) CD solution concentration and (iii ...
Celebioglu, A., Uyar, T.
openaire   +5 more sources

Investigation of molecular aggregation mechanism of glipizide/cyclodextrin complexation by combined experimental and molecular modeling approaches

open access: yesAsian Journal of Pharmaceutical Sciences, 2019
Cyclodextrin complexation is a wise strategy to enhance aqueous solubility of water-insoluble drugs. However, the aggregation mechanism of drug-cyclodextrin complexes is still unclear.
Tianhe Huang   +3 more
doaj   +1 more source

Novel β-cyclodextrin–eosin conjugates

open access: yesBeilstein Journal of Organic Chemistry, 2017
Eosin B (EoB) and eosin Y (EoY), two xanthene dye derivatives with photosensitizing ability were prepared in high purity through an improved synthetic route.
Gábor Benkovics   +8 more
doaj   +1 more source

α-Cyclodextrin extracts diacylglycerol from insect high density lipoproteins

open access: yesJournal of Lipid Research, 2000
α-Cyclodextrins are water-soluble cyclic hexamers of glucose units with hydrophobic cavities capable of solubilizing lipophiles. Incubating α-cyclodextrin with high density lipophorin from Manduca sexta or Bombyx mori resulted in a cloudy, turbid ...
Zeina E. Jouni   +5 more
doaj   +1 more source

Effects of RAMEA-complexed polyunsaturated fatty acids on the response of human dendritic cells to inflammatory signals

open access: yesBeilstein Journal of Organic Chemistry, 2014
The n−3 fatty acids are not produced by mammals, although they are essential for hormone synthesis and maintenance of cell membrane structure and integrity.
Éva Rajnavölgyi   +4 more
doaj   +1 more source

Design, synthesis, and characterization of a series of novel β-cyclodextrin functional monomers

open access: yesJournal of Chemical Research, 2022
In order to increase its solubility in water and improve β-cyclodextrin combination with guest molecules, chemical modification of β-cyclodextrin is a feasible and effective method.
Zhimin Liu, Zhigang Xu, Liping Ma
doaj   +1 more source

Identification of β -cyclodextrin inclusion complex by infrared spectroscopy

open access: yesФармацевтичний журнал, 2018
Fast and reliable identification of obtaining product is very important in the industrial technology of synthesis of pharmaceutical substances. Objective - to study inclusion complexes of β-cyclodextrin with α-bromizovalerian acid and β-cyclodextrin ...
I. O. Omelchenko   +3 more
doaj   +1 more source

Cyclodextrins in Parkinson’s Disease [PDF]

open access: yesBiomolecules, 2018
Parkinson’s disease is a movement disorder characterized by a progressive degeneration of dopaminergic neurons that has been object of study by the scientific community through the last decades. However, nowadays there is still no treatment to cure it, although there are drugs available, with limited efficacy, to relieve the symptoms or replenish the ...
Barros, Marisa C. F.   +2 more
openaire   +4 more sources

Investigation of Cytotoxicity and Cell Uptake of Cationic Beta-Cyclodextrins as Valid Tools in Nasal Delivery

open access: yesPharmaceutics, 2020
Cyclodextrin polymers have high applicability in pharmaceutical formulations due to better biocompatibility, solubility enhancement, loading capacity and controlled drug release than their parent, cyclodextrins.
Giovanna Rassu   +7 more
doaj   +1 more source

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