Results 41 to 50 of about 75,442 (304)

Molecular Interpenetration within the Columnar Structure of Crystalline Anilino-β-cyclodextrin

open access: yes, 2016
A single crystal of mono(6-anilino-6-deoxy)-β-cyclodextrin was prepared, and its crystal structure was determined by X-ray crystallographic analysis, which clearly revealed that the anilino groups are consecutively included intermolecularly into the ...
Takehiko Wada (313500)   +5 more
core   +2 more sources

Intranasal 17β-Estradiol Modulates Spatial Learning and Memory in a Rat Model of Surgical Menopause

open access: yesPharmaceutics, 2020
Exogenously administered 17β-estradiol (E2) can improve spatial learning and memory, although E2 also exerts undesired effects on peripheral organs. Clinically, E2 has been solubilized in cyclodextrin for intranasal administration, which enhances brain ...
Alesia V. Prakapenka   +7 more
doaj   +1 more source

New Polymorph of β-Cyclodextrin with a Higher Bioavailability

open access: yesChemistry, 2023
A new polymorph of anhydrous β-cyclodextrin (polymorph III) was obtained and characterized for the first time using powder X-ray diffraction, infrared spectroscopy, and thermal analysis.
Askar K. Gatiatulin   +4 more
doaj   +1 more source

Investigation of Cytotoxicity and Cell Uptake of Cationic Beta-Cyclodextrins as Valid Tools in Nasal Delivery

open access: yesPharmaceutics, 2020
Cyclodextrin polymers have high applicability in pharmaceutical formulations due to better biocompatibility, solubility enhancement, loading capacity and controlled drug release than their parent, cyclodextrins.
Giovanna Rassu   +7 more
doaj   +1 more source

What makes cyclodextrin glycosyltransferase a transglycosylase [PDF]

open access: yes, 2003
All living organisms need energy from their environment for maintenance and growth. The carbohydrate starch is such an energy source. It is an abundant carbohydrate composed of amylose and amylopectin polymers. Before organisms can utilize the starch, it
Leemhuis, Reinder Johannes,   +1 more
core  

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Titanocene / cyclodextrin supramolecular systems: a theoretical approach

open access: yesChemistry Central Journal, 2012
Background Recently, various metallocenes were synthesized and analyzed by biological activity point of view (such as antiproliferative properties): ruthenocenes, cobaltoceniums, titanocenes, zirconocenes, vanadocenes, niobocenes, molibdocenes etc.
Riviş Adrian   +3 more
doaj   +1 more source

Weakening the nuclear envelope: Lamin B receptor in melanoma metastasis

open access: yesMolecular Oncology, EarlyView.
LBR‐driven nuclear fragility supports melanoma invasion. A: Melanocyte presents low LBR (Lamin B Receptor) levels, maintaining nuclear integrity and lamina‐chromatin tethering. B: During malignant progression, upregulation of LBR clusters at the INM (Inner Nuclear Membrane) during confined migration causes local lamina weakening and cholesterol ...
Francesca Lorenzini   +1 more
wiley   +1 more source

Host–Guest Complex of β-Cyclodextrin and Disulfide Form of 4-Aminothiophenol

open access: yesApplied Sciences, 2012
An inclusion complex of β-cyclodextrin and 4-aminothiophenol was assembled by hydrophobic interaction of the host (β-cyclodextrin) and guest (4-aminothiophenol).
Taylor A. Cappadona   +2 more
doaj   +1 more source

Aptamer‐Based Delivery Systems for VEGF and NGF Modulation in Ocular Therapies

open access: yesAdvanced Healthcare Materials, EarlyView.
Aptamer‐based delivery systems targeting NGF and VEGF hold significant potential for precise and sustained treatment of complex diseases affecting both the anterior and posterior segments of the eye. This review critically summarizes current strategies for NGF and VEGF delivery as well as VEGF sequestration, providing a clinical perspective on how ...
Nadine Best   +5 more
wiley   +1 more source

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