Results 51 to 60 of about 75,442 (304)
Brazilian Journal of Pharmaceutical Sciences, 2019 Albendazole and fenbendazole are imidazole derivatives that exhibit broad spectrum activity against parasites, but the low solubility of these drugs considerably reduces their effectiveness. Complexation of albendazole and fenbendazole with cyclodextrins
Leticia Norma Carpentieri Rodrigues +4 more
doaj +1 more source
Shellac‐Mediated Assembly of Nanoparticles for mRNA Delivery
Advanced Healthcare Materials, EarlyView.A shellac‐mediated nanoparticle assembly strategy is presented, involving the complexation of mRNA and low‐molecular‐weight cationic molecules (e.g., polyethyleneimine, chitosan, lipids, and poly‐l‐lysine), followed by capping with shellac. This nanoparticle platform enables mRNA transfection following intravenous injection and facilitates gene editing
Meizhang Lu +7 more
wiley +1 more source
Repetitive stability study of remdesivir/cyclodextrin complex on the international space station
Scientific ReportsStability assessment of drugs in space is particularly important for future missions. In space there are multiple factors, such as the variability of the conditions (radiation, microgravity, vacuum etc.) that could affect the reliability and ...
György Dormán +7 more
doaj +1 more source
Cyclodextrin-Modified Gold Nanospheres
, 2016 A new procedure for the modification of gold nanospheres (2−7 nm diameter) with thiolated cyclodextrin receptors is described. The resulting monolayer-protected nanoparticles behave as multisite hosts in aqueous media, engaging in host−guest interactions
Jian Liu (33711) +4 more
core +1 more source
Epidermal Patch Technologies for Integrated Healthcare and Infection Management
Advanced Healthcare Materials, EarlyView.Epidermal patches have evolved from simple wound coverings into multifunctional, skin‐conformable platforms integrating drug delivery, biosensing, and therapeutic functionalities. This review highlights their material innovations, fabrication strategies, and intelligent designs, including hydrogels, microneedles, and flexible electronics, while ...
Yuqi Wang +7 more
wiley +1 more source
Beilstein Journal of Organic Chemistry, 2015 Novel (S)-camptothecin–dextran polymers were obtained by “click” grafting of azide-modified (S)-camptothecin and alkyne-modified dextrans. Two series based on 10 kDa and 70 kDa dextrans were prepared with a degree of substitution of (S)-camptothecin ...
Thorbjørn Terndrup Nielsen +6 more
doaj +1 more source
Хімія, фізика та технологія поверхні, 2016 Aromatic compounds are organic contaminants in aqueous streams of various industries. Even at low concentration, benzene and its derivatives are toxic agents.
I. M. Trofymchuk +2 more
doaj +1 more source
Frontiers in Molecular Biosciences, 2021 Cyclodextrins (CDs) are cyclic oligosaccharides capable of forming water-soluble complexes with a variety of otherwise poorly soluble molecules including cholesterol and different drugs. Consistently, CDs are widely used in research and clinical practice
Tamas Kovacs +6 more
doaj +1 more source
Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy
Advanced Materials, EarlyView.Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa +3 more
wiley +1 more source
Separation of folinic acid diastereomers in capillary electrophoresis using a new cationic β-cyclodextrin derivative. [PDF]
PLoS ONE, 2015 A method for the separation of folinic acid diastereomers by capillary electrophoresis in chiral separation media was developed. Aiming to achieve a good separation of the anionic analytes, a newly synthesized cationic β-cyclodextrin derivative, mono-6 ...
Jia Yu +5 more
doaj +1 more source