Results 61 to 70 of about 88,849 (292)

Binding Ability and Self-Assembly Behavior of Linear Polymeric Supramolecules Formed by Modified β-Cyclodextrin

open access: yes, 2016
The binding ability and self-assembly behavior of molecular interpenetration by newly synthesized mono[6-O-(4-formyl-phenyl)-β-cyclodextrin has been investigated, revealing the formation mechanism of modified cyclodextrin from solution aggregation to ...
Zhi Fan (2652442)   +3 more
core   +1 more source

Acid‐Responsive Nanobot‐Integrated Core‐Shell Microneedles Reprogram the Degenerative Annulus Fibrosus Microenvironment Through Epigenetic Suppression of Ferroptosis

open access: yesAdvanced Science, EarlyView.
An acid‐responsive core‐shell microneedle system normalizes the degenerative annulus fibrosus microenvironment by consuming pathological H+, generating O2, and providing NIR‐amplified redox buffering. Mechanistically, it epigenetically suppresses ferroptosis via DNMT3A‐dependent methylation of the ATF3 promoter, relieving ATF3‐mediated repression of ...
Lu Tan   +7 more
wiley   +1 more source

Precision Matters: Minor Concentration Deviations of DMSO May Cause Major Efficacy Shifts

open access: yesAngewandte Chemie, EarlyView.
Low‐concentration dimethyl sulfoxide (DMSO) has long been regarded as biologically safe in drug discovery. However, increasing DMSO from 0.1% to 0.9% reduces photosensitizer PNA‐9 particle size from 657 nm to 260 nm, enhancing endocytosis and photodynamic therapy outcomes.
Sisi Yuan   +6 more
wiley   +2 more sources

Bioelectrochemically Powered Out‐of‐Equilibrium Hydrogels Enable Feedback‐Regulated Functions

open access: yesAdvanced Science, EarlyView.
A bioelectrochemically powered hydrogel operates far from equilibrium via an antagonistic redox cycle that regulates disulfide exchange within a polyrotaxane network. Coupling electrochemical mediator cycling with enzymatic feedback enables dynamic control of hydrogel mechanics and transport properties, driving glucose‐responsive insulin release with ...
Roberto Baretta, Marco Frasconi
wiley   +1 more source

The effect of α-cyclodextrin and β-cyclodextrin as stabilizing agents on the size of gold nanoparticles

open access: yes, 2022
This study aimed to examine the effects of α-cyclodextrin and β-cyclodextrin as stabilizing agents on gold nanoparticles (AuNPs) reduced by o-hydroxybenzoic acid.
Santosa, Sri Juari   +6 more
core  

Porphyrin‐Based Porous Materials for Antibacterial Applications

open access: yesAdvanced Science, EarlyView.
Porphyrin‐based porous materials have excellent photophysical properties and tunable structures for high‐efficiency antibacterial therapy. This review comprehensively discusses the structural design strategies and synthetic pathways of the four main types of porphyrin‐based porous materials, summarizes their cross‐domain antimicrobial applications, and
Xiao‐Xue Liang   +4 more
wiley   +1 more source

Cyclodextrin production by Bacillus lehensis isolated from cassava starch: Characterisation of a novel enzyme

open access: yesCzech Journal of Food Sciences, 2014
The properties of a previously unknown enzyme, denominated cyclodextrin glycosyltransferase, produced from Bacillus lehensis, were evaluated using affinity chromatography for protein purification.
Kate Cristina Blanco   +5 more
doaj   +1 more source

Modulation of Presynaptic Inhibitory Retinal Circuits for Retinal Ganglion Cell Neuroprotection in Glaucoma

open access: yesAdvanced Science, EarlyView.
Ocular hypertension induces early hyperactivity in inner retinal inhibitory circuitry before substantial retinal ganglion cell loss. Sustained pharmacological inhibition of GABAergic/glycinergic neurotransmission and Vgat‐targeted Lin28 expression suppress this hyperactivity and improve RGC survival without reducing intraocular pressure. These findings
Eunji Hong   +7 more
wiley   +1 more source

Comparison of Association Constants of Cyclodextrins and Their tert-Butyl Derivatives With Halogenbenzoic Acids and Acridine Derivatives

open access: yesMolecules, 2001
Association constants of complexes of a new class of cyclodextrin alkyl derivatives - randomly susbstituted tert-butyl derivatives (TB-CDs) with complete set of mono-halobenzoic acids and acridine derivatives were measured using capillary electrophoresis
Josef Jůza   +4 more
doaj   +1 more source

Synthesis of beta-cyclodextrin trimers for novel polymer networks

open access: yes, 2011
Polymer hydrogels are formed by networks of polymer chains that are water-soluble. Polymer hydrogels have been extensively studied because of their potential applications in a broad range of fields.1 Our recent studies have generated a range of hydrogels
Nguyen, H.T.   +5 more
core  

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