Results 1 to 10 of about 36,946 (234)

Chitosan-EDTA-cellulose functionalized with β-cyclodextrin as a pH-sensitive bio-based nanocarrier for curcumin drug delivery [PDF]

Scientific Reports
In this work, chitosan/cellulose/β-cyclodextrin nanostructure was synthesized by cross-linking chitosan and cellulose with EDTA followed by bridging with ethylenediamine-β-cyclodextrin.
Negin Rostami, Mohammad G. Dekamin, Mohammad Reza Naimi-Jamal   +2 more
doaj   +2 more sources

Supramolecular encapsulation of indigo with β-cyclodextrin and Hydroxypropyl-β-cyclodextrin: a sustainable strategy for enhanced solubility, stability, and reducing agent-free dyeing processes [PDF]

Bioresources and Bioprocessing
Indigo, a ubiquitous vat dye in denim manufacturing, is characterized by its exceptionally low aqueous solubility, necessitating chemical reduction to its leuco form using hazardous agents such as sodium dithionite.
Koijam Monica Devi, Nimya Krishnan, Chan-Seo Yeo, Kwon-Young Choi   +3 more
doaj   +2 more sources

The Biological Fate of Pharmaceutical Excipient β-Cyclodextrin: Pharmacokinetics, Tissue Distribution, Excretion, and Metabolism of β-Cyclodextrin in Rats

Molecules, 2022
β-cyclodextrin has a unique annular hollow ultrastructure that allows encapsulation of various poorly water-soluble drugs in the resulting cavity, thereby increasing drug stability.
Kunqian Mu, Kaiwen Jiang, Yue Wang, Zihan Zhao, Song Cang, Kaishun Bi, Qing Li, Ran Liu   +7 more
doaj   +1 more source

Weak complexation of 5-fluorouracil with β-cyclodextrin, carbonate, and dianhydride crosslinked β-cyclodextrin: in vitro and in silico studies

Research in Pharmaceutical Sciences, 2022
Background and purpose: Several pharmaceutical formulations were investigated to improve the solubility of 5-fluorouracil to enhance bioavailability and therapeutic efficacy. This study aimed to examine the potential use of cyclodextrin-based nanosponges
Hadeia Mashaqbeh, Rana Obaidat, Nizar A Al-Shar’i, Tamam El-Elimat, Soraya Alnabulsi   +4 more
doaj   +1 more source

Cyclodextrin: A prospective nanocarrier for the delivery of antibacterial agents against bacteria that are resistant to antibiotics

Heliyon, 2023
Supramolecular chemistry introduces us to the macrocyclic host cyclodextrin, which has a hydrophobic cavity. The hydrophobic cavity has a higher affinity for hydrophobic guest molecules and forms host-guest complexation with non-covalent interaction ...
Pranoy Saha, Md Rajdoula Rafe
doaj   +1 more source

Design, Preparation and Evaluation of Supramolecular Complexes with Curcumin for Enhanced Cytotoxicity in Breast Cancer Cell Lines

Pharmaceutics, 2022
Curcumin is one of the most researched phytochemicals by pharmacologists and formulation scientists to unleash its potential therapeutic benefits and tackle inherent biopharmaceutic problems.
Hamdy Abdelkader, Adel Al Fatease, Zeinab Fathalla, Mai E. Shoman, Heba A. Abou-Taleb, Mohammed A. S. Abourehab   +5 more
doaj   +1 more source

New Polymorph of β-Cyclodextrin with a Higher Bioavailability

Chemistry, 2023
A new polymorph of anhydrous β-cyclodextrin (polymorph III) was obtained and characterized for the first time using powder X-ray diffraction, infrared spectroscopy, and thermal analysis.
Askar K. Gatiatulin, Ilya S. Balakhontsev, Sofia M. Talashmanova, Marat A. Ziganshin, Valery V. Gorbatchuk   +4 more
doaj   +1 more source

Design, synthesis, and characterization of a series of novel β-cyclodextrin functional monomers

Journal of Chemical Research, 2022
In order to increase its solubility in water and improve β-cyclodextrin combination with guest molecules, chemical modification of β-cyclodextrin is a feasible and effective method.
Zhimin Liu, Zhigang Xu, Liping Ma
doaj   +1 more source

Thermal Degradation of Linalool-Chemotype Cinnamomum osmophloeum Leaf Essential Oil and Its Stabilization by Microencapsulation with β-Cyclodextrin

Molecules, 2021
The thermal degradation of linalool-chemotype Cinnamomum osmophloeum leaf essential oil and the stability effect of microencapsulation of leaf essential oil with β-cyclodextrin were studied.
Hui-Ting Chang, Chun-Ya Lin, Li-Sheng Hsu, Shang-Tzen Chang   +3 more
doaj   +1 more source

Separation of folinic acid diastereomers in capillary electrophoresis using a new cationic β-cyclodextrin derivative. [PDF]

PLoS ONE, 2015
A method for the separation of folinic acid diastereomers by capillary electrophoresis in chiral separation media was developed. Aiming to achieve a good separation of the anionic analytes, a newly synthesized cationic β-cyclodextrin derivative, mono-6 ...
Jia Yu, Xinlei Liang, Zhaokun Wang, Xin Guo, Tiemin Sun, Xingjie Guo   +5 more
doaj   +1 more source