Results 11 to 20 of about 36,946 (234)

Insulin Complexation with Cyclodextrins—A Molecular Modeling Approach

Molecules, 2022
Around 5% of the population of the world is affected with the disease called diabetes mellitus. The main medication of the diabetes is the insulin; the active form is the insulin monomer, which is an instable molecule, because the long storage time, or ...
Pálma Bucur, Ibolya Fülöp, Emese Sipos   +2 more
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Investigation of molecular aggregation mechanism of glipizide/cyclodextrin complexation by combined experimental and molecular modeling approaches

Asian Journal of Pharmaceutical Sciences, 2019
Cyclodextrin complexation is a wise strategy to enhance aqueous solubility of water-insoluble drugs. However, the aggregation mechanism of drug-cyclodextrin complexes is still unclear.
Tianhe Huang, Qianqian Zhao, Yan Su, Defang Ouyang   +3 more
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INCLUSION COMPLEXES OF NICARDIPINE - HCl FOR ORAL ADMINISTRATION [PDF]

Bulletin of Pharmaceutical Sciences. Assiut University, 2005
Inclusion complexes of nicardipine HCl (NIC) with β-cyclodextrin (β-CD) and hydroxypropyl-β-cyclodextrin (HP-β-CD) were prepared using different methods: coevaporation, kneading and co-precipitation.
G. Atia, S. Ghareeb, M. Issa, H. El-Ghamry, O. Sammour, F. Ghazy   +5 more
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Formation and Physico-Chemical Evaluation of Nifedipine-hydroxypropyl-β-cyclodextrin and Nifedipine-methyl-β-cyclodextrin: The Development of Orodispersible Tablets

Pharmaceuticals, 2022
The novelty in this study is the development of new orodispersible tablets containing nifedipine (NIF) as the active ingredient. Initially, the formation of inclusion complexes between nifedipine and two derivatives of beta-cyclodextrin, namely ...
Emma Adriana Ozon, Marian Novac, Daniela Gheorghe, Adina Magdalena Musuc, Mirela Adriana Mitu, Iulian Sarbu, Valentina Anuta, Adriana Rusu, Simona Petrescu, Irina Atkinson, Dumitru Lupuliasa   +10 more
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Identification of β -cyclodextrin inclusion complex by infrared spectroscopy

Фармацевтичний журнал, 2018
Fast and reliable identification of obtaining product is very important in the industrial technology of synthesis of pharmaceutical substances. Objective - to study inclusion complexes of β-cyclodextrin with α-bromizovalerian acid and β-cyclodextrin ...
I. O. Omelchenko, T. G. Yarnyh, I. B. Yanchuk, G. I. Borschevskiy   +3 more
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An Optimization Procedure for Preparing Aqueous CAR/HP-CD Aggregate Dispersions

Molecules, 2021
β-Carotene is a very important molecule for human health. It finds a large application in the food industry, especially for the development of functional foods and dietary supplements. However, β-carotene is an unstable compound and is sensitive to light,
Enrika Celitan, Ruta Gruskiene, Jolanta Sereikaite   +2 more
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Combined Computational and Experimental Studies of Anabasine Encapsulation by Beta-Cyclodextrin

Plants, 2022
The encapsulation of the famous alkaloid, anabasine, with β-CD was studied to obtain a more stable and bioavailable inclusion complex. Various in silico and experimental studies of the obtained β-CD-anabasine complex are presented.
Zeinolla Muldakhmetov, Serik Fazylov, Oral Nurkenov, Arstan Gazaliev, Akmaral Sarsenbekova, Irina Pustolaikina, Zhangeldy Nurmaganbetov, Olzhas Seilkhanov, Aisha A. Alsfouk, Eslam B. Elkaeed, Ibrahim H. Eissa, Ahmed M. Metwaly   +11 more
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In-vitro diffusion study of ibuprofen--cyclodextrin inclusion complex nanogel [PDF]

Pharmaciana, 2021
The inclusion complex is one way to enhance active substance solubility, affecting medicine dissolution and penetration. The inclusion complex is formed by utilizing b-cyclodextrin as the host of the active compounds.
Fitrianti Darusman, Debby Prihasti Ayustine, Saadiya Noerman, Sani Ega Priani, Widad Aghnia Shalannandia   +4 more
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Photostability of piroxicam in the inclusion complex with 2-hydroxypropyl-β-cyclodextrin [PDF]

Hemijska Industrija, 2014
The aim of this work is the protection of piroxicam from photodegradation by forming inclusion complex with 2-hydroxypropyl-β-cyclodextrin. Piroxicam:2-hydroxypropyl-β-cyclodextrin molecular inclusion complex was prepared by coprecipitation ...
Nikolić Vesna D., Ilić-Stojanović Snežana S., Nikolić Ljubiša B., Cakić Milorad D., Zdravković Aleksandar S., Kapor Agneš J., Popsavin Mirjana M.   +6 more
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Formation of nanoparticles by cooperative inclusion between (S)-camptothecin-modified dextrans and β-cyclodextrin polymers

Beilstein Journal of Organic Chemistry, 2015
Novel (S)-camptothecin–dextran polymers were obtained by “click” grafting of azide-modified (S)-camptothecin and alkyne-modified dextrans. Two series based on 10 kDa and 70 kDa dextrans were prepared with a degree of substitution of (S)-camptothecin ...
Thorbjørn Terndrup Nielsen, Catherine Amiel, Laurent Duroux, Kim Lambertsen Larsen, Lars Wagner Städe, Reinhard Wimmer, Véronique Wintgens   +6 more
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