Results 81 to 90 of about 46,196 (262)

Poly(lactic‐co‐glycolic acid) microsphere loaded dissolving microneedles for sustained and coordinated transdermal delivery of desogestrel and ethinyl estradiol

Bulletin of the Korean Chemical Society, EarlyView.
PLGA‐based sustained‐release microneedles were developed for the delivery of desogestrel and ethinyl estradiol. The system enabled coordinated release of both drugs, suggesting its potential to improve dosing convenience as a long‐acting contraceptive platform.
Young‐Jin Kim, Byeongsu Kim, Sokyoung Joo, So‐Jeong Jeong, Chang‐Soo Han, Chun‐Woong Park   +5 more
wiley   +1 more source

Investigation on Cyclodextrin Production with Cyclodextrin Glucanotransferase from Bacillus megaterium

Food Technology and Biotechnology, 2008
The process of producing cyclodextrins from starch with cyclodextrin glucanotransferase from Bacillus megaterium has been studied. The effect of starch and enzyme concentrations was evaluated using optimal composite designs and the response surface ...
Ivan Genov Pishtiyski, Veselin Stanchev Stanchev, Boriana Yordanova Zhekova   +2 more
doaj  

Overcoming intranasal delivery barriers with ultrastable polyzwitterionic siRNA nanocages for enhanced glioblastoma therapy

BMEMat, EarlyView.
A ROS‐responsive, zwitterionic nanocage enables stable, intranasal siRNA delivery to glioblastoma, promoting deep tumor penetration via non‐degradative pathways and trigeminal nerve transport. This platform achieves durable gene silencing and tumor suppression, offering a non‐invasive, storage‐stable strategy for treating glioma and other neurological ...
Jingwen Xie, Jingxing Si, Xiaobei Deng, Jing Tan, Ruijie Zhu, Jizhou Qi, Gaoxia Ma, Bin Wang, Yi Wang, Yunzhou Guo, Yuping Chen, Shiqun Shao, Youqing Shen   +12 more
wiley   +1 more source

Влияние клатратных комплексов β-циклодекстрина с регуляторами роста на морфологические и биохимические показатели барвинка малого Vinca minor L.

Фактори експериментальної еволюції організмів, 2014
Aims. Study of the influence of clathrate complex of в-cyclodextrin with traditional growth regulators on morphological and biochemical parameters of periwinkle in the culture in vitro Methods. Insertion of growth regulators into в-cyclodextrin.
Л. Г. Лёшина, О. В. Булко, С. П. Рогальский, О. П. Тарасюк, О. А. Егоров   +4 more
doaj  

Advanced nanotherapeutics for combating ocular infections: Rational design, antimicrobial mechanisms, and therapeutic breakthroughs

BMEMat, EarlyView.
Nanomaterials revolutionize ocular infection treatment by enabling targeted drug delivery and enhanced antimicrobial efficacy against resistant pathogens. This review systematically explores their rational design, multimodal mechanisms, and translational potential for next‐generation anti‐infective therapies.
Yujia Liu, Xuetian Wen, Yue Tan, Rui Zeng, Yijuan Zhang, Tong Lin, Lan Gong, Zichao Luo   +7 more
wiley   +1 more source

Achievements in Preparation of Cyclodextrin–Based Porous Materials for Removal of Pollutants

Separations
Cyclodextrin–based porous materials have been widely applied in removing various organic pollutants from water environments, due to their unique physical and chemical properties, like the size–matching effect and hydrophobic interaction. Large numbers of
Kaiyue Bao, Anyun Zhang, Yiyao Cao, Lei Xu   +3 more
doaj   +1 more source

Transfersomes with core and surface‐loaded NF‐κB p65 siRNA for enhanced transdermal transfection and effective treatment of psoriasis

BMEMat, EarlyView.
TCPL, a transfersome with Tween 80 and PEI, enables efficient transdermal siNF‐κB delivery, resolving PEI's toxicity issue. It promotes lysosomal escape and effective transfection, silences NF‐κB, modulates immunity, and inhibits angiogenesis, alleviating psoriasis. With good biocompatibility, TCPL holds strong clinical translation potential. Schematic
Hui Xing, Yuhui Yang, Ziyi Zhao, Kai Lv, Yiran Shao, Zhi Zhang, Dong Ma   +6 more
wiley   +1 more source

Cyclodextrins, Surfactants and Their Inclusion Complexes

Molecules
Herein, a brief overview of the cyclodextrin structure is provided, along with its most important derivatives. The difference between the water molecules in the outer hydration shell of cyclodextrin and those in its hydrophobic cavities is discussed. The
Ana Pilipović, Vesna Tepavčević, Dileep Kumar, Mihalj Poša   +3 more
doaj   +1 more source

Conjugated Conductive Polymer Binders for Lithium Batteries: Structural Engineering and Design Principles

Carbon Energy, EarlyView.
Structural engineering of conjugated conductive polymer binders enables integrated electronic transport, strong adhesion, and stable electrode interfaces, offering a promising strategy to reduce inactive components and improve the performance of high‐energy lithium batteries.
Fating Wang, Fei Lv, Jingjing Guo, Min Hong, Xia Wang, Xiaohan Cai, Tiefeng Liu, Jun Lu   +7 more
wiley   +1 more source

Dynamic Control of Nucleic Acids Self‐Assembly and Expression Using Photoswitches

Chemistry – A European Journal, EarlyView.
We review here the recent progress made in the design of molecular photoswitches, and highlight their implementation for the dynamic control over nucleic acids self‐assembly and expression. ABSTRACT Synthetic nucleic acids have become readily available and now constitute versatile building blocks in materials science—where they can be used to engineer ...
Noemí Nogal, Hugo Laigle, Maxime Mansy, Sébastien Ulrich, Mathieu Surin   +4 more
wiley   +1 more source